Publication

[Heterotopic ossification - from the aetiology to the current management]

Journal Paper/Review - Jul 1, 2008

Units
PubMed
Doi

Citation
Gautschi O, Cadosch D, Bauer S, Filgueira L, Zellweger R. [Heterotopic ossification - from the aetiology to the current management]. Der Unfallchirurg 2008; 111:523-34.
Type
Journal Paper/Review (Deutsch)
Journal
Der Unfallchirurg 2008; 111
Publication Date
Jul 1, 2008
Issn Print
0177-5537
Pages
523-34
Brief description/objective

Heterotopic ossifications (HO) are defined as the abnormal formation of bone in soft tissues. It can be classified into acquired and congenital forms. The acquired form, of which the pathogenesis is not fully understood, is often diagnosed in patients with traumatic brain injury, spinal cord injury, musculo-skeletal trauma or injuries associated with burns. HO presents itself mostly asymptomatically, the symptoms of the initial stadium are often unspecific; however, severe forms can lead to severe disability. Imaging techniques, foremost bone szintigraphy, are mostly used for verification of the diagnosis. Local radiotherapy and nonsteroidal anti-inflammatory drugs are the classical therapeutic and prophylactic options. In advanced stages, surgical resection may be required.