Publication

Spondylodiscitis due to anaerobic bacteria : Case report and literature review

Journal Paper/Review - Sep 30, 2021

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Citation
Ziga M, Gianoli D, Waldeck F, Dennler C, Schlichtherle-Pohle R, Forster T, Martens B, Schwizer R. Spondylodiscitis due to anaerobic bacteria : Case report and literature review. Surg Neurol Int 2021; 12:496.
Project
Type
Journal Paper/Review (English)
Journal
Surg Neurol Int 2021; 12
Publication Date
Sep 30, 2021
Issn Print
2229-5097
Issn Electronic
Pages
496
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Brief description/objective

Background
While pyogenic spondylodiscitis due to Gram-positive aerobic bacteria and its treatment is well known, spondylodiscitis caused by anaerobic Gram-negative pathogen is rare. In particular, the spondylodiscitis caused by species is an absolute rarity. Thus no established management recommendations exist.

Case Description
A case report of a 79-year-old man with spondylodiscitis caused by with intramuscular abscess collection managed conservatively with stand-alone antibiotic therapy without a spinal stabilization procedure. A review of literature of all reported spondylodiscitis caused by species was performed. After 3 week-intravenous therapy with the ceftriaxone in combination with the metronidazole followed by 3 weeks per oral therapy with amoxicillin/clavulanate, the complete recovery of the patient with the infection was achieved.

Conclusion
Treatment of the spondylodiscitis caused by species should contain a beta-lactam with beta-lactamase inhibitor or third-generation cephalosporine. Six weeks of treatment seem to be sufficient for the complete recovery of the patient.