Publication
Spondylodiscitis due to anaerobic bacteria : Case report and literature review
Journal Paper/Review - Sep 30, 2021
Ziga Michal, Gianoli Daniele, Waldeck Frederike, Dennler Cyrill, Schlichtherle-Pohle Rainer, Forster Thomas, Martens Benjamin, Schwizer Roman
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PubMed
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Citation
Type
Journal
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Issn Print
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Brief description/objective
Background
While pyogenic spondylodiscitis due to Gram-positive aerobic bacteria and its treatment is well known, spondylodiscitis caused by anaerobic Gram-negative pathogen is rare. In particular, the spondylodiscitis caused by species is an absolute rarity. Thus no established management recommendations exist.
Case Description
A case report of a 79-year-old man with spondylodiscitis caused by with intramuscular abscess collection managed conservatively with stand-alone antibiotic therapy without a spinal stabilization procedure. A review of literature of all reported spondylodiscitis caused by species was performed. After 3 week-intravenous therapy with the ceftriaxone in combination with the metronidazole followed by 3 weeks per oral therapy with amoxicillin/clavulanate, the complete recovery of the patient with the infection was achieved.
Conclusion
Treatment of the spondylodiscitis caused by species should contain a beta-lactam with beta-lactamase inhibitor or third-generation cephalosporine. Six weeks of treatment seem to be sufficient for the complete recovery of the patient.