[A several-week history of inflammatory changes in the right foot and right hand of a 57-year-old male patient]
Journal Paper/Review - May 18, 2021
von Lucadou M, Strahm Carol, Potz S, Toepfer Andreas, Weber M, Passavanti Z, Neumann T
Metastatic fat necrosis due to inflammatory or neoplastic pancreatic diseases is rare. This phenomenon is attributed to systemic effects of pancreatic enzymes. Depending on the sites of fat necrosis, a number of different diseases may be mimicked, leading to incorrect diagnosis and therapies. Many case reports describe the phenomenon of skin, joint and bone manifestations of fat necrosis under the acronym PPP (pancreatic, panniculits, polyarthritis) syndrome. The management of "autodigestion" primarily consists of treating the underlying pancreatic disease.