Incidence and Outcome of Aneurysmal Subarachnoid Hemorrhage: The Swiss Study on Subarachnoid Hemorrhage (Swiss SOS)

Publication

Incidence and Outcome of Aneurysmal Subarachnoid Hemorrhage: The Swiss Study on Subarachnoid Hemorrhage (Swiss SOS)

Journal Paper/Review - Dec 4, 2020

Schaller Karl, Finkenstädt Sina, Dan-Ura Hiroki, Ferrari Andrea, Bernays René, Eisenring Christian, Maduri Rodolfo, Mostaguir Khaled, Kulcsar Zsolt, Maldaner Nicolai, Woernle Christoph, Starnoni Daniele, Z'Graggen Werner, Gasche Yvan, Sarrafzadeh Asita, Jakob Stephan M, Bijlenga Philippe, Keller Emanuela, Raabe Andreas, Beck Jürgen, Guzman Raphael, Mariani Luigi, Landolt Hans, Hildebrandt Gerhard, Levivier Marc, Regli Luca, Baumann Fabian, Corniola Marco, Gralla Jan, Diepers Michael, Nevzati Edin, D Alonzo Donato, Reinert Michael, Marbacher Serge, Bervini David, Burkhardt Jan-Karl, Daniel Roy Thomas, Zumofen Daniel, Smoll Nicolas R, Fandino Javier, Fathi Ali R, Stienen Martin N, Fung Christian, Ahlborn Peter, Mendes Pereira Vitor, Roethlisberger Michel, Goldberg Johannes, Schöni Daniel, Rohde Veit, Robert Thomas, Sailer Martin, Perren Fabienne, Venier Alice, Woernle Kerstin, Weyerbrock Astrid, Remonda Luca, Kerkeni Hassen, Seule Martin, Schatlo Bawarjan

Citation

Schaller K, Finkenstädt S, Dan-Ura H, Ferrari A, Bernays R, Eisenring C, Maduri R, Mostaguir K, Kulcsar Z, Maldaner N, Woernle C, Starnoni D, Z'Graggen W, Gasche Y, Sarrafzadeh A, Jakob S, Bijlenga P, Keller E, Raabe A, Beck J, Guzman R, Mariani L, Landolt H, Hildebrandt G, Levivier M, Regli L, Baumann F, Corniola M, Gralla J, Diepers M, Nevzati E, D Alonzo D, Reinert M, Marbacher S, Bervini D, Burkhardt J, Daniel R, Zumofen D, Smoll N, Fandino J, Fathi A, Stienen M, Fung C, Ahlborn P, Mendes Pereira V, Roethlisberger M, Goldberg J, Schöni D, Rohde V, Robert T, Sailer M, Perren F, Venier A, Woernle K, Weyerbrock A, Remonda L, Kerkeni H, Seule M, Schatlo B. Incidence and Outcome of Aneurysmal Subarachnoid Hemorrhage: The Swiss Study on Subarachnoid Hemorrhage (Swiss SOS). Stroke 2020; 52:344-347.

Type

Journal Paper/Review (English)

Journal

Stroke 2020; 52

Publication Date

Dec 4, 2020

Issn Electronic

1524-4628

Pages

344-347

Brief description/objective

BACKGROUND AND PURPOSE
The purpose of this study was to assess nationwide incidence and outcomes of aneurysmal subarachnoid hemorrhage (aSAH). The Swiss SOS (Swiss Study on Subarachnoid Hemorrhage) was established in 2008 and offers the unique opportunity to provide this data from the point of care on a nationwide level.

METHODS
All patients with confirmed aneurysmal subarachnoid hemorrhage admitted between January 1, 2009 and December 31, 2014, within Switzerland were recorded in a prospective registry. Incidence rates were calculated based on time-matched population data. Admission parameters and outcomes at discharge and at 1 year were recorded.

RESULTS
We recorded data of 1787 consecutive patients. The incidence of aneurysmal subarachnoid hemorrhage in Switzerland was 3.7 per 100 000 persons/y. The number of female patients was 1170 (65.5%). With a follow-up rate of 91.3% at 1 year, 1042 patients (58.8%) led an independent life according to the modified Rankin Scale (0-2). About 1 in 10 patients survived in a dependent state (modified Rankin Scale, 3-5; n=185; 10.4%). Case fatality was 20.1% (n=356) at discharge and 22.1% (n=391) after 1 year.

CONCLUSIONS
The current incidence of aneurysmal subarachnoid hemorrhage in Switzerland is lower than expected and an indication of a global trend toward decreasing admissions for ruptured intracranial aneurysms. Registration: URL: https://www.clinicaltrials.gov. Unique identifier: NCT03245866.