Projects
Search from 1147 projects:
1147 Project(s)
Predictive and prognostic value of integrated exon-level expression to approach drug-response and resistance to EGFR-targeted treatment in non-small cell lung cancer
Jan 1, 2015Activating mutations in lung cancer are targeted by a series of molecularly targeted therapies. Patients harboring such mutations can receive significant benefit from these therapies. However a proportion of patients without activating mutations can...
Fundamental Research - Jan 1, 2015 - Dec 31, 2016
Automatically Closed
Project leader: Baty Florent
Members: Franzini Anca, Früh Martin, Jörger Markus, Brutsche Martin
GA28950/Hickory
Jan 1, 2015PHASE III, BLINDED, PLACEBO-CONTROLLED, MULTICENTER STUDY OF THE EFFICACY AND SAFETY OF ETROLIZUMAB DURING INDUCTION AND MAINTENANCE IN PATIENTS WITH MODERATE TO SEVERE ACTIVE ULCERATIVE COLITIS WHO ARE REFRACTORY TO OR INTOLERANT OF TNF INHIBITORS
Clinical Studies - Jan 1, 2015 - Dec 31, 2017
Automatically Closed
Project leader: Borovicka Jan
Members: Dora Barbara, Frei Remus, Knellwolf Christina, Semadeni Gian-Marco, Sulz Michael
SINGLE ARM OPEN LABLE PHASE II PILOT STUDY OF CARBOPLATIN
Dec 2, 2014Study design: For the pilot trial a single stage phase II design was chosen. All patients that meet the eligibility criteria will receive carboplatin AUC3 until progression (radiological or clinical). A total of 25 patients are required for this stud...
Clinical Studies - Dec 2, 2014 - Dec 31, 2017
Automatically Closed
Project leader: Omlin Aurelius
Members: Gillessen Sommer Silke, Haile Sarah, Jochum Wolfram
Fibromyalgie: A Randomized, Double-Blind, Placebo- and Active-Controlled Study of DS-5565 for Treatment of Pain Associated with Fibromyalgia
Nov 16, 2014This is a randomized, double-blind, double-dummy, placebo- and active controlled, multi-center study of DS-5565 in subjects with pain associated with FM. Eligible subjects will be randomized in the ratio of 1:1:1:1 to receive 13 weeks of treatment wi...
Clinical Studies - Nov 16, 2014 - May 31, 2017
Completed
Project leader: Müller Rüdiger
Members: Forrer Silvia
Clinical impact of multiplex realtime PCR in respiratory tract infections
Nov 15, 2014Pathogen detection in respiratory tract infections is challenging due to lack of diagnostic gold standard with sufficient sensitivity and specificity. Viral infections likely contribute to a considerable portion of respiratory tract infections partic...
Clinical Studies - Nov 15, 2014 - Dec 31, 2015
Automatically Closed
Project leader: Albrich Werner
Members: Kahlert Christian, Rassouli Frank, Mayer Lena
"Mechanisms of Evasive Resitance in Cancer (MERiC)"
Nov 1, 2014-prospektive Beobachtungsstudie von Patienten mit HCC -Leberbiopsie vom Leberrundherd, Re-Biopsie bei Tumorprogression nach jeder Behandlung (TACE etc.) bis Behandlungsende HCC
Clinical Studies - Nov 1, 2014 - Nov 1, 2020
Automatically Closed
Project leader: Semela David
Members: Alfter Christine, Pérez Shibayama Christian Ivan
A national palliative care database: A tool to better define the needs of palliative care patients in Switzerland - SwissPALL
Nov 1, 2014
Clinical Studies - Nov 1, 2014 - Jan 1, 2016
Completed
Project leader: Büche Daniel, Strasser Florian
Members: Domeisen Benedetti Franzisca, Forster Michaela
MP0250; A phase I multi-centre, open-label, repeated-dose, dose-escalation study to assess safety, tolerability and pharmacokinetics of MP0250 in patients with advanced solid tumours
Oct 23, 2014Dies ist die erste Studie zur Anwendung des neuen Medikaments MP0250 am Menschen. Das Hauptziel ist es, dessen Sicherheit und Verträglichkeit bei Krebs-Patienten zu untersuchen. Diese Studie wird auch prüfen, wie das Medikament durch den Körper verä...
Clinical Studies - Oct 23, 2014 - Sep 30, 2016
Automatically Closed
Project leader: Omlin Aurelius
Members: Hess Dagmar, Jörger Markus, Bickel Angelika
SCAD: Spontaneous coronary artery dissection: single centre study with systematic angiographic and clinical follow-up
Oct 16, 2014The aim of the study is to describe clinical characteristics, treatment, and angiographic/clinical follow-up of a contemporary SCAD population in which a large proportion of patients was treated conservatively, i.e. no mechanical revascularization bu...
Clinical Studies - Oct 16, 2014 - Dec 31, 2020
Completed
Project leader: Maeder Micha
Members: Rogowski Sebastian, Schneider Irene
SAKK 63/12 Prospective cohort study with collection of clinical data and serum of patients with prostate disease
Oct 15, 2014Diese Studie umfasst die Erstellung einer Serum- und Gewebebank, sowie die Erhebung zugehöriger klinischer Daten.
Clinical Studies - Oct 15, 2014 - Oct 15, 2024
Ongoing
Project leader: Engeler Daniel, Gillessen Sommer Silke
Members: Rothermundt Christian, Omlin Aurelius, Putora Paul Martin, Lengwiler Daniel, Patzl Sigrid, Schaepper Sibylle, Schwab Christoph, Abt Dominik, Templeton Arnoud
Verteilung der Werte des Proliferationsmarkers Ki-67 am Kantonsspital St.Gallen
Oct 15, 20141b.1. Hintergrund Der Proliferationsmarker Ki-67 wird in der Onkologie ubiquitär verwendet. Bei der Behandlung von Brustkrebs hat er ein spezielles Gewicht bekommen, da bei einem häufigen Subtyp von Brustkrebs (Luminal-B) die Indikation für eine adju...
Clinical Studies - Oct 15, 2014 - Sep 26, 2015
Completed
Project leader: Ruhstaller Thomas
Members: Öhlschlegel Christian, Jochum Wolfram, Thürlimann Beat
Timed-up-and-go (TUG) as a generic objective measure of function in neurosurgery. Relationship to subjective measures of pain and function and quality of life
Oct 5, 2014This prospective, observational study examines the relationship between pain, functional disability and health-related quality of life (HRQoL) with the result of a simple test, the “timed-up-and-go”-Test (TUG-test) in patients with lumbar spinal dege...
Clinical Studies - Oct 5, 2014 - Oct 31, 2015
Automatically Closed
Project leader: Stienen Martin N., Corniola Marco V, Smoll Nicolas R., Gautschi Oliver P
Members: Chau Ivan, Joswig Holger, Hildebrandt Gerhard
M13-375SpoA: A Multicenter, Randomized, Double-Blind, Study Comparing the Efficacy and Safety of
Sep 9, 2014Das Ziel dieser Studie ist es, die Wirksamkeit und Sicherheit der Fortsetzung vs. des Abbruchs der Therapie mit Adalimumab 40 mg, das jede zweite Woche subkutan verabreicht wird, in Bezug auf die Aufrechterhaltung der Remission bei Probanden mit nich...
Clinical Studies - Sep 9, 2014 - Apr 7, 2017
Completed
Project leader: Müller Rüdiger
Members: Forrer Silvia
Evaluation of a Candidate Vaccine Against Uropathogenic Escherichia Coli in Women With a Clinical History of Recurrent Urinary Tract Infection
Sep 7, 2014Purpose: This Phase I multi-center placebo controlled study is conducted in healthy women with a history of recurrent urinary tract infections (UTI) aged between 18 and 70 years. GlycoVaxyn is a Swiss company that has developed a multivalent bioconju...
Healthcare Research - Sep 7, 2014 - Sep 7, 2015
Completed
Project leader: Hülder Tanja, Hornung René
Airway microbiota resistome in CF - impact on clinical management
Sep 1, 2014Cystic Fibrosis is a deadly genetic disease mainly due to chronic bacterial colonization and recurrent bacterial infections of the lungs. It has often been documented that once a certain microbial species such as Pseudomonas aeruginosa establishes, t...
Fundamental Research - Sep 1, 2014 - Dec 31, 2016
Automatically Closed
Project leader: Baty Florent
Members: Brutsche Martin, Kahlert Christian, Von Mering Christian, Vyas Rounak
PsoA: A phase III, randomized, double-blind, placebo-controlled multicenter
Aug 20, 2014Study to demonstrate the efficacy at 24 weeks and to assess the long term efficacy, safety and tolerability of secukinumab in Active Psoriatic Arthritis
Clinical Studies - Aug 20, 2014 - Aug 16, 2018
Completed
Project leader: Müller Rüdiger
Members: Forrer Silvia, Bartz-Batliner Mira, Hutz Carina Liane, Schmidig Kathrin
LVNC: Multicenter Registry for Left Ventricular Non-compaction Cardiomyopathy
Aug 18, 20141. To set up an internet-based multicenter registry for patients with LVNC. 2. To include a minimum of 200 patients with LVNC in the registry. 3. To determine complications (type, incidence, recurrence) and prognosis of patients with LVNC. Obje...
Clinical Studies - Aug 18, 2014 - Mar 31, 2024
Completed
Project leader: Haager Philipp K.
Members: Schneider Irene
ABreak: Abatacept Study to omit weekly subcutaneous injections in RA patients during holiday BREAK
Aug 7, 2014Einmalige Infusion von Abatacept zur Simulation von Ferien bei Patienten mit rheumatoider Arhtritis und Vorbehandlung mit Abatacept (Wechsel von sc auf iv und zurück).
Clinical Studies - Aug 7, 2014 - Dec 7, 2014
Completed
Project leader: Müller Rüdiger
Qualitative Interviews Runder Tisch in palliativer Situation - Teil 1 des Konzeptes Palliative Betreuung
Aug 4, 2014Seit Einführung des Konzeptes Palliative Betreuung (ehemaliger Standard 25) erheben wir vor allem quantitative Daten zur Auswertung des Standards. 2011 wurden die Multiplikatorinnen und Multiplikatoren befragt. Befragungen von Betroffenen zum Runden...
Clinical Studies - Aug 4, 2014 - Dec 1, 2015
Completed
Project leader: Büche Daniel, Grossenbacher-Gschwend Barbara, Domeisen Benedetti Franzisca
Members: Mettler Mona
A structured early palliative care intervention for patients with advanced cancer – a randomized controlled trial with a nested qualitative study - SENS Trial
Aug 1, 2014Dieses Studienprojekt, der SENS-Trial, möchte untersuchen, inwiefern eine systematische Diskussion dieser Fragen, zu einem möglichst frühen Zeitpunkt im Krankheitsverlauf zu einer erkennbaren Stressreduktion sowohl bei den Patienten, aber auch bei de...
Clinical Studies - Aug 1, 2014 - Dec 31, 2016
Automatically Closed
Project leader: Eychmuller Steffen, Nestor Karen
Members: Domeisen Benedetti Franzisca, Forster Michaela