Projects
Search from 1147 projects:
1147 Project(s)
A Phase 1b/2 Multicenter, Open-label, Expansion Study to As-sess the Safety and Efficacy of AMG 420 as Monotherapy in Subjects With Relapsed and/or Refractory Multiple Myeloma
Dec 5, 2019Bispezifische, T-Zell-aktivierende Antikörper (BITE) sind eine vielversprechende Option, um eine zellvermittelte Immuntherapie von Tumoren zu erreichen. In der vorlie-genden Studie wird die Wirksamkeit und Sicherheit eines gegen das Oberflächenantige...
Clinical Studies - Dec 5, 2019 - Dec 23, 2020
Automatically Closed
Project leader: Driessen Christoph
Members: Silzle Tobias
Six-Minute Walking Test (6WT) as a measure of objective functional impairment in lumbar spinal stenosis. Validation and realtionship to subjective measure of pain, function and quality of life
Dec 1, 2019Background: Lumbar spinal stenosis (LSS) is a progressive, degenerative disorder of the aging spine presenting with lower back pain, which commonly progresses into neurogenic claudication which impedes walking. The precise measurement of symptom seve...
Clinical Studies - Dec 1, 2019 - May 1, 2022
Automatically Closed
Project leader: Maldaner Nicolai
XATOA – Xarelto + Acetylsalicylic Acid: Treatment
Nov 19, 2019The study aims to collect real-world data on treatment patterns and decision points for treatment in patients with coronary artery disease (CAD) or symptomatic peripheral artery disease (PAD) treated with rivaroxaban 2.5 mg[BID] for the prevention of...
Clinical Studies - Nov 19, 2019 - Dec 21, 2021
Completed
Project leader: Rickli Hans
Members: Fink Karin
Developing an EEG-based approach to DBS-frequency modulation in Parkinson’s disease
Nov 1, 2019
Clinical Studies - Nov 1, 2019 - Dec 31, 2021
Automatically Closed
Project leader: Brugger Florian
Members: Dorin Patrick
Regionale Netzwerke für die fachärztliche Weiterbildung
Nov 1, 2019Netzwerke sind modern und gelten auch als Hoffnungsträger für die fachärztliche Weiterbildung. Inwieweit vermeintliche Vorteile vom ärztlichen Nachwuchs tatsächlich als solche wahrgenommen werden, ist jedoch unklar. Das Forschungsprojekt sollte kläre...
Healthcare Research - Nov 1, 2019 - Jan 31, 2022
Completed
Project leader: Thanner Mirjam
Members: Winder Franziska, Schlegel A, Von Szadkowski C, Hornung René
RA Bridge
Oct 3, 2019A Randomized, Active-Controlled, Parallel-Group, Phase 3b/4 Study of Baricitinib in Patients with Rheumatoid Arthritis
Clinical Studies - Oct 3, 2019 - Jul 30, 2023
Automatically Closed
Project leader: Rubbert-Roth Andrea
Members: Bartz-Batliner Mira, Neumann Thomas, Sasselli Clelia, Peischl Riana
Swiss Severe Asthma Register
Oct 1, 2019
Clinical Studies - Oct 1, 2019 - Dec 31, 2021
Automatically Closed
Project leader: Kern Lukas
Members: Baty Florent, Widmer Sandra, Brutsche Martin
STOP FLU
Oct 1, 2019Die jährliche Impfung ist die vorrangige Strategie zur Grippevorbeugung und wird für Transplantationspatienten dringend empfohlen. Leider ist die Wirksamkeit des Standardimpfstoffes bei Patienten, welche eine Organtransplantation hatten, im Vergleich...
Clinical Studies - Oct 1, 2019 - Jul 1, 2020
Completed
Project leader: Binet Françoise-Isabelle
Arimoclomol in Amyotropic Lateral Sclerosis - Open Label Extension Trial
Sep 19, 2019A multicenter, non-randomized, open label trial, to assess long term safety and efficacy of Arimoclomol in subjects with Amyotrophic Lateral Sclerosis (ALS)who have completed the ORARIALS-01 trial.
Clinical Studies - Sep 19, 2019 - Jul 2, 2021
Aborted
Project leader: Neuwirth Christoph
SAKK 66/18: A phase Ib trial of copanlisib in combina-tion with venetoclax in patients with relapsed or refrac-tory lymphoma
Sep 13, 2019A significant number of patients with non-Hodgkin lym-phoma (NHL) are not cured with available treatments and will eventually relapse. Those patients might not be able to tolerate more bone marrow toxicity, limiting their treatment options. Preclinic...
Clinical Studies - Sep 13, 2019 - Dec 31, 2022
Automatically Closed
Project leader: Hess Dagmar
A phase I/Ib, open-label, multi-center dose escalation study of NIS793 in combination with PDR001 in adult patients with advanced malignancies (CNIS793X2101)
Sep 9, 2019This is a first-in-human (FIH), open label, phase I/Ib, multi-center study which consists of: - a dose escalation part of NIS793 as single agent and in combination with PDR001. Patients treated with NIS793 single agent will switch to NIS793 in combin...
Clinical Studies - Sep 9, 2019 - Jul 1, 2021
Automatically Closed
Project leader: Jörger Markus
Akromegalie-Register
Sep 6, 2019Akromegalie ist ein sehr seltene Erkrankungen, deren Behandlung in vielerlei Hinsicht noch nicht ausreichend erforscht ist. Eine effektive Erforschung dieser Erkrankung setzt voraus, dass möglichst umfangreiche Informationen über möglichst viele Pati...
Clinical Studies - Sep 6, 2019 - Dec 31, 2029
Ongoing
Project leader: Krull Ina
Members: Bilz Stefan, Räss Andrea
COSMIC 312
Sep 1, 2019A Randomized, Controlled Phase 3 Study of Cabozantinib (XL184) in Combination with Atezolizumab versus Sorafenib in Subjects with Advanced Hepatocellular Carcinoma Who Have Not Received Previous Systemic Anticancer Therapy Randomisation 2:1:1:1 Cabo...
Clinical Studies - Sep 1, 2019 - Nov 28, 2020
Completed
Project leader: Semela David
Members: Stillhard Roman
AEGIS II_CSL112_3001
Aug 7, 2019A Phase 3, Multicenter, Double-blind, Randomized, Placebo-controlled, Parallel-group Study to Investigate the Efficacy and Safety of CSL112 in Subjects with Acute Coronary Syndrome
Clinical Studies - Aug 7, 2019 - Aug 30, 2020
Aborted
Project leader: Rickli Hans
Members: Vetsch Susanne
Emotions
Aug 1, 2019Untersuchung wie gut Menschen mit ALS, Emotionen in Gesichtsausdrücken erkennen können. Falls Resultate des Projekts ergeben sollte, dass ALS-Patienten in der Erkennung von Emotionen eingeschränkt sind, soll der im Rahmen des Projekts durchgeführte T...
Clinical Studies - Aug 1, 2019 - Dec 31, 2024
Ongoing
Project leader: Braun Nathalie
Amgen CC-10004-PsA-014 MOSAIK
Jul 31, 2019A PHASE 4, MULTICENTER, SINGLE-ARM, OPENLABEL STUDY TO EVALUATE THE IMPACT OF APREMILAST (CC-10004) ON MRI OUTCOMES IN SUBJECTS WITH PSORIATIC ARTHRITIS
Clinical Studies - Jul 31, 2019 - Aug 31, 2021
Completed
Project leader: Rubbert-Roth Andrea
Members: Bartz-Batliner Mira, Neumann Thomas, Sasselli Clelia, Peischl Riana
SAKK 01/18 Reduced intensity radio-chemotherapy for satge IIA/B seminoma. A multicenter, open label phase II trial with 2 cohorts
Jul 24, 2019Main objective: To investigate efficacy of a stage-adapted tratment regimen in stage IIA/B seminoma based on the preliminary experience gained in SAKK 01/10. The Goal is to further safely de-escalate Treatment while maintaining / enhancing efficacy.
Clinical Studies - Jul 24, 2019 - Jul 24, 2030
Ongoing
Project leader: Putora Paul Martin
Members: Plasswilm Ludwig, Rothermundt Christian, Patzl Sigrid, Fischer Stefanie
MATAO - eine Studie zur Behandlung von Frauen mit Eierstockkrebs in einem fortgeschrittenen Stadium
Jul 18, 2019MATAO- MAintenance Therapie mit Aromatasehemmer (Letrozol) für Patientinnen mit epithelialem Ovarialkarzinom: Eine randomisierte doppel-blinde Placebo-kontrollierte Phase III Studie inklusive LOGOS (LOw Grade Ovarian cancer Sub-study) (ENGOT-ov54/S...
Clinical Studies - Jul 18, 2019 - Dec 31, 2025
Ongoing
Project leader: Hornung René
Members: Baldinger Jeannette, Kozlova Aleksandra
Sanofi PMR EFC15160
Jul 4, 2019A randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of sarilumab in patients with polymyalgia rheumatica
Clinical Studies - Jul 4, 2019 - Jul 8, 2021
Automatically Closed
Project leader: Rubbert-Roth Andrea
Members: Neumann Thomas, Bartz-Batliner Mira, Peischl Riana, Sasselli Clelia
Sanofi GCA EFC15068
Jul 4, 2019A randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of sarilumab in patients with giant cell arteritis
Clinical Studies - Jul 4, 2019 - Jul 8, 2020
Aborted
Project leader: Rubbert-Roth Andrea
Members: Neumann Thomas, Bartz-Batliner Mira, Peischl Riana, Sasselli Clelia