Project

The Neuroprotective Effect of Lamotrigine and Interferon Beta 1a in Patients With Relapsing-Remitting Multiple Sclerosis

Automatically Closed · 2009 until 2011

Type
Clinical Studies
Range
Monocentric project at KSSG
Units
Status
Automatically Closed
Start Date
2009
End Date
2011
Financing
Industry
Study Design
randomized, placebo-controlled, MRI rater blinded study
Keywords
MS, neuroprotection, phase II, interferon-beta
Homepage
Brief description/objective

Randomized, Placebo-Controlled Phase II Monocentric Trial for the Neuroprotective Effect of Lamotrigine Plus Interferon Beta 1a 30mcg Once Weekly Intramuscular in Patients With Relapsing-Remitting Multiple Sclerosis.

Primary Outcome Measures:
N-Acetyl-Aspartate / creatine - quotient in normal appearing white matter by MR-spectroscopy [ Time Frame: 12 months ]
Safety of lamotrigine in combination with interferon beta 1a (30 mcg) once weekly intramuscular. [ Time Frame: 6 months, 12 months ]