Project
Efficacy and safety of drotrecogin alfa (activated) in adult patients with septic shock
Completed ยท 2009 until 2011
Kleger Gian-Reto
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Brief description/objective
Coagulation disturbances are a mayor event in severe sepsis and septic shock. Activated protein C may reduce mortality in these patients by its antiinflammatory, antithrombotic and antifibrinolytic effect. However, bleeding complications are more frequent.