Fiona Müller
Medizinische Onkologie und Hämatologie · Dept. I
An Open-Label, Multicenter, Phase 1b/2 Study of the Safety and Efficacy of KRT-232 in Combination with Acalabrutinib in Subjects with Relapsed/Refractory Dif-fuse Large B-cell Lymphoma or Relapsed/Refractory Chronic Lymphocytic Leukemia
Apr 28, 2021Aclabrutinib wird in Kombination mit KRT 232 bei R/R CLL und de novo R/R DLBCL jeweils TP 53 WT und BTK naiv eingesetzt. Initial Dosisescalations-stufe (Ib), anschlies-send Phase-II mit RP2D. Primärer Endpunkt: Dosisfin-dung/ Safety ; Efficacy in Ph...
Clinical Studies - Apr 28, 2021 - May 20, 2030
Ongoing
Project leader: Hess Dagmar
Members: Scherrer Julia, Müller Fiona
INCMOR0208-301
Apr 20, 2021A PHASE 3, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTICENTER TRIAL TO EVALUATE THE EFFICACY AND SAFETY OF TAFASITAMAB PLUS LENALIDOMIDE IN ADDITION TO RITUXIMAB VERSUS LENALIDOMIDE IN ADDITION TO RITUXIMAB IN PATIENTS WITH RELAPSED/REFRACTORY...
Clinical Studies - Apr 20, 2021 - Dec 31, 2099
Ongoing
Project leader: Fehr Martin
Members: Bürki Ramona, Müller Fiona
Swiss Soliris® and Ultomiris® Reimbursement Registry SSURR: An observational registry for capturing data of patients suffering from paroxysmal nocturnal hemoglobinuria (PNH) who are treated with Soliris® (eculizumab) or Ultomiris® (ravulizumab)
Jan 1, 2021
Clinical Studies - Jan 1, 2021 - Dec 31, 2030
Ongoing
Project leader: Silzle Tobias
Members: Demmer-Steingruber Ruth, Müller Fiona
IPSEN F-FR-60000-023
Jul 17, 2020A Phase II Multicentre, Open-Labe- Study of Cabozantinib as 2nd Line Treatment in Subjects with unresectable, locally advanced Metastatic Renal Cell Carcinoma wiht a Clear- Cell Componentn who progressed after 1st Line Treatment with Checkpoint inhib...
Clinical Studies - Jul 17, 2020 - Dec 31, 2099
Ongoing
Project leader: Aeppli Stefanie
Members: Harder Anja, Müller Fiona
Immune-modulatory radiotherapy to enhance the effects of neoadjuvant PD - L1 blockade after neoadjuvant chemotherapy in patients with resectable stage III ( N2) non -small cell lung cacner (NSCLC)
Apr 29, 2020Evaluation einer immunmodulatorischen neoadjuvanten Radiotherapie in verschiedenen Dosen nach neoadjuvanter Chemotherapie mit Cisplatin und Docetaxel bei Patienten mit operablem, lokal fortgeschrittenem (Stadium IIIA) Nicht-Kleinzelligen Bronchialkar...
Clinical Studies - Apr 29, 2020 - Aug 24, 2030
Ongoing
Project leader: Früh Martin
Members: Hutter Franziska, Müller Fiona
Achiles MO40379
Jan 29, 2020A randomized phase II study comparing atezolizumab after concurrent chemoradiotherapy with chemoradiotherapy alone in limited disease small-cell lung cancer
Clinical Studies - Jan 29, 2020 - Dec 31, 2030
Ongoing
Project leader: Appenzeller-Herzog Christian
Members: Demmer-Steingruber Ruth, Müller Fiona
EMCL-Register Lymphoma
Dec 20, 2019THE REGISTRY OF THE EUROPEAN MANTLE CELL LYMPHOMA STUDY GROUP FOCUSSING ON INDOLENT MCL AND RELAPSED MCL
Clinical Studies - Dec 20, 2019 - Dec 31, 2099
Ongoing
Project leader: Fehr Martin
Members: Munz Jeannine, Müller Fiona
A phase I/Ib, open-label, multi-center dose escalation study of NIS793 in combination with PDR001 in adult patients with advanced malignancies (CNIS793X2101)
Sep 9, 2019This is a first-in-human (FIH), open label, phase I/Ib, multi-center study which consists of: - a dose escalation part of NIS793 as single agent and in combination with PDR001. Patients treated with NIS793 single agent will switch to NIS793 in comb...
Clinical Studies - Sep 9, 2019 - Oct 18, 2024
Completed
Project leader: Horber Daniel
Members: Müller Fiona, Hutter Franziska
Beat-meso ETOP 13-18
Jun 20, 2019A multicentre randomised phase III trial comparing atezolizumab plus bevacizumab and standard chemotherapy versus bevacizumab and standard chemotherapy as first-line treatment for advanced malignant pleural mesothelioma
Clinical Studies - Jun 20, 2019 - Dec 31, 2099
Ongoing
Project leader: Früh Martin
Members: Breuss Kim, Müller Fiona
IELSG 45
Jun 7, 2019A randomized, open-label, multicentre, two-arm phase III comparative study assessing the role of involved mediastinal radiotherapy after Rituximab containing chemotherapy regimens to patients with newly diagnosed Primary Mediastinal Large B-Cell Lymp...
Clinical Studies - Jun 7, 2019 - Dec 31, 2099
Ongoing
Project leader: Fehr Martin
Members: Kern Julia, Müller Fiona
BMS CA027-002
Apr 15, 2019A Phase 1/2a Study of BMS-986253 in Combination with Nivolumab in Advanced Cancers.
Clinical Studies - Apr 15, 2019 - Dec 31, 2099
Ongoing
Project leader: Jörger Markus
Members: Hutter Franziska, Müller Fiona
Prospective Observational international Registry of Patients with newly diagnosed peripheral T-Cell Lymphoma
Jan 1, 2019
Clinical Studies - Jan 1, 2019 - Dec 31, 2030
Ongoing
Project leader: Hitz Felicitas
Members: Demmer-Steingruber Ruth, Müller Fiona
MK-3475-495: KeylmPaCT
Dec 12, 2018A Phase 2 Precision Oncology Study of Biomarker-Directed, Pembrolizumab- (MK-3475, SCH 900475) Based Combination Therapy for Advanced Non-Small Cell Lung Cancer (KEYNOTE-495; KeyImPaCT).
Clinical Studies - Dec 12, 2018 - Dec 31, 2099
Ongoing
Members: Fehr Martin, Kern Julia, Müller Fiona
Tailored AXILLary Surgery with or without axillary lymph node dissection followed by radotherapy in patients with clinically node-positive breast cancer (TAXIS)
Jul 31, 2018The removal of all lymph nodes in the armpit through con-ventional axillary dissection has been standard care for all patients with breast cancer for almost a century. In the nineties, the sentinel lymph node (SLN) procedure, which involves the selec...
Clinical Studies - Jul 31, 2018 - Dec 12, 2030
Ongoing
Project leader: Bekes Inga
Members: Sennhauser Andrina, Müller Fiona
SAKK 06/17
May 22, 2018Neoadjuvant and adjuvant durvalumab in combination with neoadjuvant chemotherapy in patients with operable urothelial cancer. A Multicenter, Single-arm Phase II Trial.
Clinical Studies - May 22, 2018 - Dec 31, 2099
Ongoing
Project leader: Aeppli Stefanie
Members: Breuss Kim, Müller Fiona
TRIANGLE
Feb 20, 2018Autologous Transplantation after a Rituximab/Ibrutinib/Ara-c containing iNduction in Generalized mantle cell Lymphoma – a randomized European MCL Network trial.
Clinical Studies - Feb 20, 2018 - Dec 31, 2099
Ongoing
Project leader: Fehr Martin
Members: Demmer-Steingruber Ruth, Müller Fiona
SAKK 07/17
Jan 4, 2018Nivolumab in combination with Ipilimumab in patients with metastatic renal cell carcinoma: A multicentre single-arm phase lI trial.
Clinical Studies - Jan 4, 2018 - Dec 31, 2099
Ongoing
Project leader: Aeppli Stefanie
Members: Breuss Kim, Müller Fiona
SAKK HD 21
Jun 9, 2017Treatment optimization trial in the first-line treatment of advanced stage Hodgkin lymphoma; comparison of 6 cycles of escalated BEACOPP with 6 cycles of BrECADD.
Clinical Studies - Jun 9, 2017 - Dec 31, 2099
Ongoing
Project leader: Aeppli Stefanie
Members: Breuss Kim, Müller Fiona
PALLAS (IBCSG 52-16)
Nov 9, 2016A randomized phase III trial of Palbociclib with standard adjuvant endocrine therapy versus standard adjuvant endocrine therapy alone for hormone receptor positive (HR+) / human epidermal growth factor receptor 2 (HER2)-negative early breast cancer....
Clinical Studies - Nov 9, 2016 - Dec 31, 2099
Ongoing
Project leader: Huober Jens
Members: Munz Jeannine, Müller Fiona
SAKK HOVON 135
Oct 27, 2016A randomized phase II multicenter study to assess the tolerability and efficacy of the addition of ibrutinib to 10-day decitabine in UNFIT (i.e. HCT-CI ≥ 3) AML and high risk myelodysplasia (MDS) (IPSS-R > 4.5) patients aged ≥ 66 years.
Clinical Studies - Oct 27, 2016 - Dec 31, 2099
Ongoing
Project leader: Früh Martin
Members: Harder Anja, Müller Fiona