Janine Quinter
Medizinische Onkologie und Hämatologie · Dept. I
A Phase 1, dose-finding study of Debio 0123 as monotherapy in adult patients with advanced solid tumors, followed by an expansion part to assess safety and preliminary anti-tumor activity
Dec 20, 2024
Clinical Studies - Dec 20, 2024 - Dec 31, 2099
Ongoing
Project leader: Hess Dagmar
Members: Scherrer Julia, Quinter Janine
Addition of Darolutamide to first line treatment of mCRPC: a randomized open label phase II trial.
Oct 31, 2024
Clinical Studies - Oct 31, 2024 - Dec 31, 2099
Ongoing
Project leader: Fischer Stefanie
Members: Dei Cas Alissa, Quinter Janine
A multicenter, open-label, randomized, phase 2 study of venetoclax and azacitidine plus cusatuzumab versus venetoclax and azacitidine alone in newly diagnosed AML patients who are not candidates for intensive therapy
Oct 7, 2024
Clinical Studies - Oct 7, 2024 - Dec 31, 2099
Ongoing
Project leader: Schittenhelm Marcus
Members: Dei Cas Alissa, Quinter Janine
A phase 1/1b/2 study evaluating the safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy of AMG 193 alone and in combination with docetaxel in subjects with advanced MTAP-null solid tumors
Aug 27, 2024
Clinical Studies - Aug 27, 2024 - Dec 31, 2099
Ongoing
Project leader: Jörger Markus
Members: Bürki Ramona, Quinter Janine
A Phase 3, Open-label, Multicenter, Randomized Study of Tarlatamab in Combination With Durvalumab vs Durvalumab Alone in Subjects with Extensive-Stage Small-Cell Lung Cancer Following Platinum, Etoposide and Durvalumab (DeLLphi-305)
Aug 16, 2024
Clinical Studies - Aug 16, 2024 - Dec 31, 2099
Ongoing
Project leader: Früh Martin
Members: Hutter Franziska, Quinter Janine
A Randomized, Open-label, Phase 3 Trial of Dato-DXd Plus Pembrolizumab vs Pembrolizumab Alone in Treatment-naïve Subjects with Advanced or Metastatic PD-L1 High (TPS ≥50%) Non-small Cell Lung Cancer Without Actionable Genomic Alterations (TROPION-Lung08) (Dato-DXd Plus Pembrolizumab vs Pembrolizumab Alone in the First-line Treatment of Subjects with Advanced or Metastatic NSCLC Without Actionable Genomic Alterations)
Aug 13, 2024
Clinical Studies - Aug 13, 2024 - Dec 31, 2099
Ongoing
Project leader: Jörger Markus
Members: Harder Anja, Quinter Janine
A PHASE 3, OPEN-LABEL, RANDOMIZED STUDY TO COMPARE THE EFFICACY AND SAFETY OF ODRONEXTAMAB (REGN1979), AN ANTICD20 X ANTI-CD3 BISPECIFIC ANTIBODY, VERSUS INVESTIGATOR’S CHOICE IN PREVIOUSLY UNTREATED PARTICIPANTS WITH FOLLICULAR LYMPHOMA (OLYMPIA-1)
Apr 18, 2024
Clinical Studies - Apr 18, 2024 - Dec 31, 2099
Ongoing
Project leader: Hitz Felicitas
Members: Bürki Ramona, Quinter Janine
Liquid biopsy to diagnose and monitor central nervous system (CNS) involvement in high-risk B cell non-Hodgkin lymphoma
Apr 10, 2024
Clinical Studies - Apr 10, 2024 - Dec 31, 2099
Ongoing
Project leader: Sturm Andreas
Members: Kern Julia, Quinter Janine
An Open-label, Dose Escalation, Phase 1/2 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of TAK-676 as a Single Agent and in Combination With Pembrolizumab in Adult Patients With Advanced or Metastatic Solid Tumors
Mar 28, 2024
Clinical Studies - Mar 28, 2024 - Dec 31, 2099
Ongoing
Project leader: Hess Dagmar
Members: Hutter Franziska, Quinter Janine
Phase 2/3 Randomized Study of Tebentafusp as Monotherapy and in Combination with Pembrolizumab Versus Investigator’s Choice in HLA-A*02:01-positive Participants with Previously Treated Advanced Melanoma (TEBE-AM)
Jan 26, 2024
Clinical Studies - Jan 26, 2024 - Dec 31, 2099
Ongoing
Project leader: Aeppli Stefanie
Members: Scherrer Julia, Quinter Janine
A single-arm phase II trial of the addition of niraparib to anti-PD-L1 antibody maintenance in patients with SLFN11-positive, extensive-disease small cell lung cancer.
Dec 21, 2023
Clinical Studies - Dec 21, 2023 - Dec 31, 2027
Ongoing
Project leader: Jörger Markus
Members: Quinter Janine, Kehl Jeanine
A Phase III, Randomized, Open-Label, Multicenter, Global Study of Volrustomig (MEDI5752) in Combination with Carboplatin plus Pemetrexed Versus Platinum plus Pemetrexed or Nivolumab plus Ipilimumab in Participants with Unresectable Pleural Mesothelioma (eVOLVE-Meso)
Nov 17, 2023Forscher suchen nach einer besseren Möglichkeit, fortgeschrittenes Pleuramesotheliom zu behandeln. Pleuramesotheliom ist eine Krebsart, die die Lungenschleimhaut befällt. Fortgeschritten bedeutet in der Regel, dass der Krebs nicht operativ behandelt...
Clinical Studies - Nov 17, 2023 - Dec 31, 2099
Ongoing
Project leader: Früh Martin
Members: Dei Cas Alissa, Quinter Janine
A Phase 3 Randomized Study Comparing Teclistamab in Combination with Daratumumab SC and Lenalidomide (Tec-DR) versus Daratumumab SC, Lenalidomide, and Dexamethasone (DRd) in Participants with Newly Diagnosed Multiple Myeloma Who are Either Ineligible or not Intended for Autologous Stem Cell Transplant as Initial Therapy
Nov 3, 2023
Clinical Studies - Nov 3, 2023 - Dec 31, 2099
Ongoing
Project leader: Baumann Michael
Members: Harder Anja, Quinter Janine
A Phase 1, Open-Label, Multicenter Study of INCA33890 in Participants With Advanced or Metastatic Solid Tumors
Oct 30, 2023
Clinical Studies - Oct 30, 2023 - Dec 31, 2099
Ongoing
Project leader: Jörger Markus
Members: Bürki Ramona, Quinter Janine
A double-blind randomised phase III trial evaluating the efficacy of ADT +/- darolutamide in de novo metastatic prostate cancer patients with vulnerable functional ability and not elected for docetaxel or androgen receptor targeted agents
Oct 18, 2023
Clinical Studies - Oct 18, 2023 - Dec 31, 2099
Ongoing
Project leader: Fischer Stefanie
Members: Harder Anja, Quinter Janine
A Randomized, Open-label, Phase 3 Study of Tarlatamab Compared With Standard of Care in Subjects with Relapsed Small Cell Lung Cancer After Platinum-based First Line chemotherapy (DeLLphi-304)
Jul 17, 2023
Clinical Studies - Jul 17, 2023 - Dec 31, 2099
Ongoing
Project leader: Früh Martin
Members: Hutter Franziska, Quinter Janine
Phase III postneoadjuvant study evaluating Sacituzumab Govitecan, an Antibody Drug Conjugate in primary HER2-negative breast cancer patients with high relapse risk after standard neoadjuvant treatment – SASCIA
Apr 26, 2023Die Studie richtet sich an Personen, die an frühem HER2-negativem Brustkrebs leiden und ein hohes Rückfallrisiko nach medikamentöser Vorbehandlung und Operation aufweisen. In dieser Studie erhalten die Teilnehmenden entweder das Medikament mit dem Wi...
Clinical Studies - Apr 26, 2023 - Dec 31, 2099
Ongoing
Project leader: Huober Jens
Members: Quinter Janine, Kehl Jeanine
A multicentre single-arm phase II trial of amivantamab, lazertinib plus bevacizumab in patients with EGFR-mutant advanced NSCLC with progression on previous third-generation EGFR-TKI
Mar 14, 2023Die klinische Studie AMAZE-lung ist für Patienten bestimmt, bei denen eine Art von Lungenkrebs diagnostiziert wurde, der als "fortgeschrittener nicht-kleinzelliger Lungenkrebs" bezeichnet wird. Der Lungenkrebs, der in dieser Studie behandelt wird, we...
Clinical Studies - Mar 14, 2023 - Dec 31, 2099
Ongoing
Project leader: Früh Martin
Members: Harder Anja, Quinter Janine
A Phase II, Multicentre, Open-label, Master Protocol to Evaluate the Efficacy and Safety of Datopotamab Deruxtecan (Dato-DXd) as Mono-therapy and in Com-bination with Anticancer Agents in Patients with Advanced/Metastatic Solid Tumours (TROPION-PanTumor03)
Mar 2, 2023
Clinical Studies - Mar 2, 2023 - Oct 2, 2023
Completed
Project leader: Jörger Markus
Members: Bürki Ramona, Quinter Janine
A Dose-Escalation and Expansion Study of the Safety and Efficacy of XL092 in Combination with Immuno-Oncology Agents in Subjects with Unresectable Advanced or Metastatic Solid Tumors
Feb 7, 2023Zweck dieser Studie ist die Bewertung potenzieller neuer Krebstherapien für inoperable, fortgeschrittene oder metastasierte solide Tumore. Die Studie soll Informationen über Sicherheit, Verträglichkeit, die Menge des Arzneimittels bzw. der Arzneimitt...
Clinical Studies - Feb 7, 2023 - Dec 31, 2099
Ongoing
Project leader: Fischer Stefanie
Members: Bürki Ramona, Quinter Janine