A Phase II, randomised, placebo-controlled, double-blind, parallel-group, efficacy and safety study of at least 48 weeks of oral BI 685509 treatment in adults with early progressive diffuse cutaneous systemic sclerosis

Clinical Studies - May 22, 2023 - May 22, 2026

Ongoing

Project leader: Rubbert-Roth Andrea
Members: Schmiedeberg Kristin, Bartz-Batliner Mira, Peischl Shirin, Gostic Dragana

A Phase 1b Randomized, Double-Blind, Placebo-Controlled, Multiple-Ascending Dose Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of ACE-1334 Plus Standard of Care in Participants with Systemic Sclerosis

Clinical Studies - Apr 14, 2023 - Apr 14, 2026

Ongoing

Project leader: Rubbert-Roth Andrea
Members: Schmiedeberg Kristin, Bartz-Batliner Mira, Peischl Shirin, Gostic Dragana

A randomized, parallel-group, double-blind, placebo-controlled, multicenter Phase3 trial to evaluate efficacy and safety of secukinumab administered subcutaneously versus placebo,in combination with a glucocorticoid taper regimen, in patients with po...

Clinical Studies - Mar 10, 2023 - Mar 10, 2026

Ongoing

Project leader: Rubbert-Roth Andrea
Members: Schmiedeberg Kristin, Bartz-Batliner Mira, Peischl Shirin, Gostic Dragana

A randomized, four-arm, canakinumab placebo-controlled, participant, investigator and sponsor-blinded study investigating the safety, tolerability and efficacy of intra-articular canakinumab followed by intra-articular LNA043 in patients with knee os...

Clinical Studies - Dec 30, 2022 - Dec 31, 2025

Ongoing

Project leader: Rubbert-Roth Andrea
Members: Schmiedeberg Kristin, Peischl Shirin, Bartz-Batliner Mira, Peischl Riana, Hutz Carina Liane

A Randomized, Double-blind, Placebo-controlled, Repeat-dose, Multicenter Trial to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of HZN-825 in Patients with Diffuse Cutaneous Systemic Sclerosis

Clinical Studies - Nov 30, 2022 - Dec 31, 2025

Ongoing

Project leader: Rubbert-Roth Andrea
Members: Schmiedeberg Kristin, Peischl Shirin, Peischl Riana, Bartz-Batliner Mira, Hutz Carina Liane

A double blind, randomized, placebo-controlled study to evaluate the efficacy and safety of PRA023 in Subject with Systemic Sclerosis associated with interstitial Lung Disease.

Clinical Studies - Aug 23, 2022 - Aug 23, 2024

Automatically Closed

Project leader: Rubbert-Roth Andrea
Members: Peischl Riana, Peischl Shirin, Bartz-Batliner Mira, Hutz Carina Liane, Schmiedeberg Kristin

A Phase 3, Randomized, Head-to-head, Single-blind Study to Compare the Response to Treatment with Subcutaneous Abatacept vs Adalimumab, on Background Methotrexate, in Adults with Early, Seropositive Rheumatoid Arthritis Who Have "Shared Epitope" HLA...

Clinical Studies - Jan 24, 2022 - Jan 17, 2025

Completed

Project leader: Rubbert-Roth Andrea
Members: Peischl Shirin, Peischl Riana, Bartz-Batliner Mira, Haller Christoph, Pirker Ian, Hutz Carina Liane

A randomized, parallel-group, double-blind, placebo-controlled, multicenter Phase III trial to investigate the efficacy and safety of secukinumab 300 mg and 150 mg administered subcutaneously versus placebo, in combination with a glucocorticoid taper...

Clinical Studies - Jan 1, 2022 - Jan 1, 2025

Ongoing

Project leader: Rubbert-Roth Andrea
Members: Schmiedeberg Kristin, Bartz-Batliner Mira, Peischl Shirin, Gostic Dragana

Real World Effectiveness of Upadacitinib on Early and Sustained Pain Control and Sleep Quality in Radiographic Axial Spondyloarthritis

Clinical Studies - Dec 10, 2021 - Dec 10, 2024

Automatically Closed

Project leader: Rubbert-Roth Andrea
Members: Bartz-Batliner Mira, Peischl Shirin, Peischl Riana, Hutz Carina Liane

Untersuchung der Sicherheit und Effektivität von mRNA basierten COVID-19 Impfungen bei Patienten mit rheumatoider Arthritis - ein exploratives Forschungsprojekt

Clinical Studies - Feb 1, 2021 - Dec 31, 2022

Completed

Project leader: Rubbert-Roth Andrea
Members: Schmiedeberg Kristin, Bartz-Batliner Mira, Peischl Riana, Peischl Shirin, Sasselli Clelia, Hutz Carina Liane

a phase 3, double-blind, multicenter study of evaluate the long-term safety and efficacy of baricitinib in patients with SLE.

Clinical Studies - Aug 12, 2020 - Aug 12, 2022

Completed

Project leader: Rubbert-Roth Andrea
Members: Peischl Riana, Bartz-Batliner Mira

Upadacitinib treatment patterns, achievement of treatment targets and maintenance of response in moderate to severe Rheumatoid Arthritis patients in real-world practice

Clinical Studies - Aug 1, 2020 - Oct 31, 2023

Automatically Closed

Project leader: Rubbert-Roth Andrea
Members: Bartz-Batliner Mira, Hutz Carina Liane, Peischl Riana, Peischl Shirin, Schmiedeberg Kristin

A two-year, phase III randomized, double-blind, parallel- group, placebo- controlled trial to evaluate the safety, efficacy, and tolerability of 300 mg s.c. secukinumab versus placebo in combination with SoC therapy in patients with active lupus neph...

Clinical Studies - Jul 13, 2020 - Jul 12, 2023

Automatically Closed

Project leader: Rubbert-Roth Andrea
Members: Bartz-Batliner Mira, Hutz Carina Liane, Peischl Riana, Sasselli Clelia

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of IgPro20 (Subcutaneous Immunoglobulin, Hizentra®) in Adults with Dermatomyositis (DM)

Clinical Studies - Feb 5, 2020 - Dec 30, 2025

Ongoing

Project leader: Rubbert-Roth Andrea
Members: Hutz Carina Liane, Bartz-Batliner Mira, Peischl Riana, Sasselli Clelia

A Randomized, Active-Controlled, Parallel-Group, Phase 3b/4 Study of Baricitinib in Patients with Rheumatoid Arthritis

Clinical Studies - Oct 3, 2019 - Jul 30, 2023

Automatically Closed

Project leader: Rubbert-Roth Andrea
Members: Bartz-Batliner Mira, Neumann Thomas, Sasselli Clelia, Peischl Riana

A PHASE 4, MULTICENTER, SINGLE-ARM, OPENLABEL STUDY TO EVALUATE THE IMPACT OF APREMILAST (CC-10004) ON MRI OUTCOMES IN SUBJECTS WITH PSORIATIC ARTHRITIS

Clinical Studies - Jul 31, 2019 - Aug 31, 2021

Completed

Project leader: Rubbert-Roth Andrea
Members: Bartz-Batliner Mira, Neumann Thomas, Sasselli Clelia, Peischl Riana

A randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of sarilumab in patients with polymyalgia rheumatica

Clinical Studies - Jul 4, 2019 - Jul 8, 2021

Automatically Closed

Project leader: Rubbert-Roth Andrea
Members: Neumann Thomas, Bartz-Batliner Mira, Peischl Riana, Sasselli Clelia

A randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of sarilumab in patients with giant cell arteritis

Clinical Studies - Jul 4, 2019 - Jul 8, 2020

Aborted

Project leader: Rubbert-Roth Andrea
Members: Neumann Thomas, Bartz-Batliner Mira, Peischl Riana, Sasselli Clelia

Giant Cell Arteritis: Phase 3 Safety and Efficacy Study of Upadacitinib in Subjects with Giant Cell Arteritis

Clinical Studies - Apr 2, 2019 - Dec 31, 2024

Ongoing

Project leader: Rubbert-Roth Andrea
Members: Hutz Carina Liane, Bartz-Batliner Mira, Neumann Thomas, Peischl Riana, Sasselli Clelia

A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Phase 3 Study of Baricitinib in Patients with systemic lupus erythematosus (SLE).

Clinical Studies - Feb 28, 2019 - Feb 28, 2022

Completed

Project leader: Rubbert-Roth Andrea
Members: Neumann Thomas, Bartz-Batliner Mira, Hutz Carina Liane, Peischl Riana, Sasselli Clelia