Stephan Forchhammer
Acidosis-mediated increase in IFN-γ-induced PD-L1 expression on cancer cells as an immune escape mechanism in solid tumors.
Knopf P, Stowbur D, Hoffmann S, Hermann N, Maurer A, Bucher V, Poxleitner M, Tako B, Sonanini D, Krishnamachary B, Sinharay S, Fehrenbacher B, Gonzalez-Menendez I, Reckmann F, Bomze D, Flatz L, Kramer D, Schaller M, Forchhammer S, Bhujwalla Z, Quintanilla-Martinez L, Schulze-Osthoff K, Pagel M, Fransen M, Röcken M, Martins A, Pichler B, Ghoreschi K, Kneilling M. Acidosis-mediated increase in IFN-γ-induced PD-L1 expression on cancer cells as an immune escape mechanism in solid tumors. Mol Cancer 2023; 22:207.
Dec 15, 2023Acidosis-mediated increase in IFN-γ-induced PD-L1 expression on cancer cells as an immune escape mechanism in solid tumors.
Dec 15, 2023Mol Cancer 2023; 22:207
Knopf Philipp, Stowbur Dimitri, Hoffmann Sabrina Hl, Hermann Natalie, Maurer Andreas, Bucher Valentina, Poxleitner Marilena, Tako Bredi, Sonanini Dominik, Krishnamachary Balaji, Sinharay Sanhita, Fehrenbacher Birgit, Gonzalez-Menendez Irene, Reckmann Felix, Bomze David, Flatz Lukas, Kramer Daniela, Schaller Martin, Forchhammer Stephan, Bhujwalla Zaver M, Quintanilla-Martinez Leticia, Schulze-Osthoff Klaus, Pagel Mark D, Fransen Marieke F, Röcken Martin, Martins André F, Pichler Bernd, Ghoreschi Kamran, Kneilling Manfred
Histopathologic regression in patients with primary cutaneous melanoma undergoing sentinel lymph node biopsy is associated with favorable survival and, after metastasis, with improved progression-free survival on immune checkpoint inhibitor therapy: A single institutional cohort study.
Wagner N, Knierim S, Luttermann F, Metzler G, Yazdi A, Bauer J, Gassenmaier M, Forschner A, Leiter U, Amaral T, Garbe C, Eigentler T, Forchhammer S, Flatz L. Histopathologic regression in patients with primary cutaneous melanoma undergoing sentinel lymph node biopsy is associated with favorable survival and, after metastasis, with improved progression-free survival on immune checkpoint inhibitor therapy: A single institutional cohort study. J Am Acad Dermatol 2023
Dec 1, 2023Histopathologic regression in patients with primary cutaneous melanoma undergoing sentinel lymph node biopsy is associated with favorable survival and, after metastasis, with improved progression-free survival on immune checkpoint inhibitor therapy: A single institutional cohort study.
Dec 1, 2023J Am Acad Dermatol 2023
Wagner Nikolaus, Knierim Sarah M, Luttermann Felix, Metzler Gisela, Yazdi Amir Sadegh, Bauer Jürgen, Gassenmaier Maximilian, Forschner Andrea, Leiter Ulrike, Amaral Teresa, Garbe Claus, Eigentler Thomas Kurt, Forchhammer Stephan, Flatz Lukas
EGFR expression is associated with relapse in a melanoma cohort receiving adjuvant PD-1-based immunotherapy.
Amaral T, Pop O, Chatziioannou E, Sinnberg T, Niessner H, Zhao J, Ring S, Jörger M, Schroeder C, Armeanu-Ebinger S, Cozzio A, Leiter U, Thomas I, Jochum W, Garbe C, Forchhammer S, Levesque M, Mangana J, Hölzel M, Dummer R, Schürch C, Forschner A, Flatz L. EGFR expression is associated with relapse in a melanoma cohort receiving adjuvant PD-1-based immunotherapy. J Am Acad Dermatol 2023; 89:1072-1074.
Jul 22, 2023EGFR expression is associated with relapse in a melanoma cohort receiving adjuvant PD-1-based immunotherapy.
Jul 22, 2023J Am Acad Dermatol 2023; 89:1072-1074
Amaral Teresa, Pop Oltin Tiberiu, Chatziioannou Eftychia, Sinnberg Tobias, Niessner Heike, Zhao Jing Hua, Ring Sandra Stephanie, Jörger Markus, Schroeder Christopher, Armeanu-Ebinger Sorin, Cozzio Antonio, Leiter Ulrike, Thomas Ioannis, Jochum Wolfram, Garbe Claus, Forchhammer Stephan, Levesque Mitchell Paul, Mangana Joanna, Hölzel Michael, Dummer Reinhard, Schürch Christian M, Forschner Andrea, Flatz Lukas
Histopathologic abundance of pigmentation correlates with disease-specific survival in malignant melanoma but is not independent of current AJCC pT stage.
Aebischer V, Abu-Ghazaleh A, Metzler G, Riedl L, Garbe C, Flatz L, Eigentler T, Forchhammer S. Histopathologic abundance of pigmentation correlates with disease-specific survival in malignant melanoma but is not independent of current AJCC pT stage. Pigment Cell Melanoma Res 2023; 36:512-521.
Jul 20, 2023Histopathologic abundance of pigmentation correlates with disease-specific survival in malignant melanoma but is not independent of current AJCC pT stage.
Jul 20, 2023Pigment Cell Melanoma Res 2023; 36:512-521
Aebischer Valentin, Abu-Ghazaleh Amar, Metzler Gisela, Riedl Lena, Garbe Claus, Flatz Lukas, Eigentler Thomas Kurt, Forchhammer Stephan
Deep learning-based scoring of tumour-infiltrating lymphocytes is prognostic in primary melanoma and predictive to PD-1 checkpoint inhibition in melanoma metastases.
Chatziioannou E, Roßner J, Aung T, Rimm D, Niessner H, Keim U, Serna-Higuita L, Bonzheim I, Kuhn Cuellar L, Westphal D, Steininger J, Meier F, Pop O, Forchhammer S, Flatz L, Eigentler T, Garbe C, Röcken M, Amaral T, Sinnberg T. Deep learning-based scoring of tumour-infiltrating lymphocytes is prognostic in primary melanoma and predictive to PD-1 checkpoint inhibition in melanoma metastases. EBioMedicine 2023; 93:104644.
Jun 7, 2023Deep learning-based scoring of tumour-infiltrating lymphocytes is prognostic in primary melanoma and predictive to PD-1 checkpoint inhibition in melanoma metastases.
Jun 7, 2023EBioMedicine 2023; 93:104644
Chatziioannou Eftychia, Roßner Jana, Aung Thazin New, Rimm David L, Niessner Heike, Keim Ulrike, Serna-Higuita Lina María, Bonzheim Irina, Kuhn Cuellar Luis, Westphal Dana, Steininger Julian, Meier Friedegund, Pop Oltin Tiberiu, Forchhammer Stephan, Flatz Lukas, Eigentler Thomas Kurt, Garbe Claus, Röcken Martin, Amaral Teresa, Sinnberg Tobias
The impact of the COVID-19 pandemic on the diagnosis of cutaneous melanomas: A retrospective cohort study from five European skin cancer reference centres.
Troesch A, Hoellwerth M, Forchhammer S, Del Regno L, Lodde G, Turko P, Cheng F, Levesque M, Hadaschik E, Livingstone E, Peris K, Flatz L, Koelblinger P, Dummer R, Dimitriou F. The impact of the COVID-19 pandemic on the diagnosis of cutaneous melanomas: A retrospective cohort study from five European skin cancer reference centres. J Eur Acad Dermatol Venereol 2023; 37:922-931.
Mar 3, 2023The impact of the COVID-19 pandemic on the diagnosis of cutaneous melanomas: A retrospective cohort study from five European skin cancer reference centres.
Mar 3, 2023J Eur Acad Dermatol Venereol 2023; 37:922-931
Troesch Alexander, Hoellwerth Magdalena, Forchhammer Stephan, Del Regno Laura, Lodde Georg, Turko Patrick, Cheng Fei, Levesque Mitchell L, Hadaschik Eva, Livingstone Elisabeth, Peris Ketty, Flatz Lukas, Koelblinger Peter, Dummer Reinhard, Dimitriou Florentia
Identification of stage I/II melanoma patients at high risk for recurrence using a model combining clinicopathologic factors with gene expression profiling (CP-GEP).
Amaral T, Sinnberg T, Chatziioannou E, Niessner H, Leiter U, Keim U, Forschner A, Dwarkasing J, Tjien-Fooh F, Wever R, Flatz L, Eggermont A, Forchhammer S. Identification of stage I/II melanoma patients at high risk for recurrence using a model combining clinicopathologic factors with gene expression profiling (CP-GEP). Eur J Cancer 2022; 182:155-162.
Dec 30, 2022Identification of stage I/II melanoma patients at high risk for recurrence using a model combining clinicopathologic factors with gene expression profiling (CP-GEP).
Dec 30, 2022Eur J Cancer 2022; 182:155-162
Amaral Teresa, Sinnberg Tobias, Chatziioannou Eftychia, Niessner Heike, Leiter Ulrike, Keim Ulrike, Forschner Andrea, Dwarkasing Jvalini, Tjien-Fooh Félicia, Wever Renske, Flatz Lukas, Eggermont Alexander, Forchhammer Stephan
Histological and Immunohistochemical Changes of Congenital Melanocytic Nevi With Age
Gassenmaier M, Häfner H, Hahn M, Kofler L, Wagner N, Forchhammer S. Histological and Immunohistochemical Changes of Congenital Melanocytic Nevi With Age. Am J Dermatopathol 2021; 43:707-713.
Oct 1, 2021Histological and Immunohistochemical Changes of Congenital Melanocytic Nevi With Age
Oct 1, 2021Am J Dermatopathol 2021; 43:707-713
Gassenmaier Maximilian, Häfner Hans-Martin, Hahn Matthias, Kofler Lukas, Wagner Nikolaus, Forchhammer Stephan
Diffuse PRAME Expression Is Highly Specific for Thin Melanomas in the Distinction from Severely Dysplastic Nevi but Does Not Distinguish Metastasizing from Non-Metastasizing Thin Melanomas
Gassenmaier M, Hahn M, Metzler G, Bauer J, Yazdi A, Keim U, Garbe C, Wagner N, Forchhammer S. Diffuse PRAME Expression Is Highly Specific for Thin Melanomas in the Distinction from Severely Dysplastic Nevi but Does Not Distinguish Metastasizing from Non-Metastasizing Thin Melanomas. Cancers (Basel) 2021; 13
Jul 31, 2021Diffuse PRAME Expression Is Highly Specific for Thin Melanomas in the Distinction from Severely Dysplastic Nevi but Does Not Distinguish Metastasizing from Non-Metastasizing Thin Melanomas
Jul 31, 2021Cancers (Basel) 2021; 13
Gassenmaier Maximilian, Hahn Matthias, Metzler Gisela, Bauer Jürgen, Yazdi Amir Sadegh, Keim Ulrike, Garbe Claus, Wagner Nikolaus, Forchhammer Stephan
Early disappearance of tumor antigen-reactive T cells from peripheral blood correlates with superior clinical outcomes in melanoma under anti-PD-1 therapy
Bochem J, Meier F, Terheyden P, Königsrainer A, Garbe C, Flatz L, Pawelec G, Eigentler T, Löffler M, Weide B, Niessner H, Sinnberg T, Zelba H, Spreuer J, Amaral T, Gaissler A, Pop O, Thiel K, Yurttas C, Soffel D, Forchhammer S, Wistuba-Hamprecht K. Early disappearance of tumor antigen-reactive T cells from peripheral blood correlates with superior clinical outcomes in melanoma under anti-PD-1 therapy. J Immunother Cancer 2021; 9
Jan 1, 2021Early disappearance of tumor antigen-reactive T cells from peripheral blood correlates with superior clinical outcomes in melanoma under anti-PD-1 therapy
Jan 1, 2021J Immunother Cancer 2021; 9
Bochem Jonas, Meier Friedegund, Terheyden Patrick, Königsrainer Alfred, Garbe Claus, Flatz Lukas, Pawelec Graham, Eigentler Thomas K, Löffler Markus W, Weide Benjamin, Niessner Heike, Sinnberg Tobias, Zelba Henning, Spreuer Janine, Amaral Teresa, Gaissler Andrea, Pop Oltin, Thiel Karolin, Yurttas Can, Soffel Daniel, Forchhammer Stephan, Wistuba-Hamprecht Kilian