Ashwin N Ananthakrishnan
Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn's disease and leads to impaired CFB cleavage and phagocytosis.
Akhlaghpour M, Haritunians T, More S, Thomas L, Stamps D, Dube S, Li D, Yang S, Landers C, Mengesha E, Hamade H, Murali R, Potdar A, Wolf A, Botwin G, Khrom M, International IBD Genetics Consortium, Ananthakrishnan A, Faubion W, Jabri B, Lira S, Newberry R, Sandler R, Sartor R, Xavier R, Brant S, Cho J, Duerr R, Lazarev M, Rioux J, Schumm L, Silverberg M, Zaghiyan K, Fleshner P, Melmed G, Vasiliauskas E, Ha C, Rabizadeh S, Syal G, Bonthala N, Ziring D, Targan S, Long M, McGovern D, Michelsen K, Brand S. Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn's disease and leads to impaired CFB cleavage and phagocytosis. Gut 2023; 72:2068-2080.
Apr 20, 2023Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn's disease and leads to impaired CFB cleavage and phagocytosis.
Apr 20, 2023Gut 2023; 72:2068-2080
Akhlaghpour Marzieh, Haritunians Talin, More Shyam K, Thomas Lisa S, Stamps Dalton T, Dube Shishir, Li Dalin, Yang Shaohong, Landers Carol J, Mengesha Emebet, Hamade Hussein, Murali Ramachandran, Potdar Alka A, Wolf Andrea J, Botwin Gregory J, Khrom Michelle, International IBD Genetics Consortium, Ananthakrishnan Ashwin N, Faubion William A, Jabri Bana, Lira Sergio A, Newberry Rodney D, Sandler Robert S, Sartor R Balfour, Xavier Ramnik J, Brant Steven R, Cho Judy H, Duerr Richard H, Lazarev Mark G, Rioux John D, Schumm L Philip, Silverberg Mark S, Zaghiyan Karen, Fleshner Phillip, Melmed Gil Y, Vasiliauskas Eric A, Ha Christina, Rabizadeh Shervin, Syal Gaurav, Bonthala Nirupama N, Ziring David A, Targan Stephan R, Long Millie, McGovern Dermot P B, Michelsen Kathrin S, Brand Stephan
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
Kupcinskas L, Potocnik U, Prescott N, Regueiro M, Rotter J, Russell R, Sanderson J, Sans M, Satsangi J, Schreiber S, Simms L, Sventoraityte J, Ponsioen C, Palmieri O, Kugathasan S, Latiano A, Laukens D, Lawrance I, Lees C, Louis E, Mahy G, Mansfield J, Morgan A, Mowat C, Newman W, Targan S, Taylor K, Tremelling M, Hakonarson H, Brant S, Radford-Smith G, Mathew C, Rioux J, Schadt E, Daly M, Franke A, Parkes M, Vermeire S, Barrett J, Annese V, Silverberg M, Verspaget H, De Vos M, Wijmenga C, Wilson D, Winkelmann J, Xavier R, Zeissig S, Zhang B, Zhang C, Zhao H, Cho J, Karlsen T, Jostins L, Theatre E, Spain S, Raychaudhuri S, Goyette P, Wei Z, Abraham C, Achkar J, Ahmad T, Amininejad L, Ananthakrishnan A, Andersen V, Cleynen I, Ning K, Ripke S, Weersma R, Duerr R, McGovern D, Hui K, Lee J, Schumm L, Sharma Y, Anderson C, Essers J, Mitrovic M, Andrews J, Baidoo L, Balschun T, Ferguson L, Franchimont D, Fransen K, Gearry R, Georges M, Gieger C, Glas J, Haritunians T, Hart A, Hawkey C, Hedl M, Ellinghaus D, Edwards C, Bampton P, Bitton A, Boucher G, Brand S, Büning C, Cohain A, Cichon S, D'Amato M, De Jong D, Devaney K, Dubinsky M, Hu X. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature 2012; 491:119-24.
Nov 1, 2012Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
Nov 1, 2012Nature 2012; 491:119-24
Kupcinskas Limas, Potocnik Uros, Prescott Natalie J, Regueiro Miguel, Rotter Jerome I, Russell Richard K, Sanderson Jeremy D, Sans Miquel, Satsangi Jack, Schreiber Stefan, Simms Lisa A, Sventoraityte Jurgita, Ponsioen Cyriel Y, Palmieri Orazio, Kugathasan Subra, Latiano Anna, Laukens Debby, Lawrance Ian C, Lees Charlie W, Louis Edouard, Mahy Gillian, Mansfield John, Morgan Angharad R, Mowat Craig, Newman William, Targan Stephan R, Taylor Kent D, Tremelling Mark, Hakonarson Hakon, Brant Steven R, Radford-Smith Graham, Mathew Christopher G, Rioux John D, Schadt Eric E, Daly Mark J, Franke Andre, Parkes Miles, Vermeire Severine, Barrett Jeffrey C, Annese Vito, Silverberg Mark S, Verspaget Hein W, De Vos Martine, Wijmenga Cisca, Wilson David C, Winkelmann Juliane, Xavier Ramnik J, Zeissig Sebastian, Zhang Bin, Zhang Clarence K, Zhao Hongyu, Cho Judy H, Karlsen Tom H, Jostins Luke, Theatre Emilie, Spain Sarah L, Raychaudhuri Soumya, Goyette Philippe, Wei Zhi, Abraham Clara, Achkar Jean-Paul, Ahmad Tariq, Amininejad Leila, Ananthakrishnan Ashwin N, Andersen Vibeke, Cleynen Isabelle, Ning Kaida, Ripke Stephan, Weersma Rinse K, Duerr Richard H, McGovern Dermot P, Hui Ken Y, Lee James C, Schumm L Philip, Sharma Yashoda, Anderson Carl A, Essers Jonah, Mitrovic Mitja, Andrews Jane M, Baidoo Leonard, Balschun Tobias, Ferguson Lynnette R, Franchimont Denis, Fransen Karin, Gearry Richard, Georges Michel, Gieger Christian, Glas Jürgen, Haritunians Talin, Hart Ailsa, Hawkey Chris, Hedl Matija, Ellinghaus David, Edwards Cathryn, Bampton Peter A, Bitton Alain, Boucher Gabrielle, Brand Stephan, Büning Carsten, Cohain Ariella, Cichon Sven, D'Amato Mauro, De Jong Dirk, Devaney Kathy L, Dubinsky Marla, Hu Xinli