Dermot P B McGovern
Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn's disease and leads to impaired CFB cleavage and phagocytosis.
Akhlaghpour M, Haritunians T, More S, Thomas L, Stamps D, Dube S, Li D, Yang S, Landers C, Mengesha E, Hamade H, Murali R, Potdar A, Wolf A, Botwin G, Khrom M, International IBD Genetics Consortium, Ananthakrishnan A, Faubion W, Jabri B, Lira S, Newberry R, Sandler R, Sartor R, Xavier R, Brant S, Cho J, Duerr R, Lazarev M, Rioux J, Schumm L, Silverberg M, Zaghiyan K, Fleshner P, Melmed G, Vasiliauskas E, Ha C, Rabizadeh S, Syal G, Bonthala N, Ziring D, Targan S, Long M, McGovern D, Michelsen K, Brand S. Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn's disease and leads to impaired CFB cleavage and phagocytosis. Gut 2023; 72:2068-2080.
Apr 20, 2023Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn's disease and leads to impaired CFB cleavage and phagocytosis.
Apr 20, 2023Gut 2023; 72:2068-2080
Akhlaghpour Marzieh, Haritunians Talin, More Shyam K, Thomas Lisa S, Stamps Dalton T, Dube Shishir, Li Dalin, Yang Shaohong, Landers Carol J, Mengesha Emebet, Hamade Hussein, Murali Ramachandran, Potdar Alka A, Wolf Andrea J, Botwin Gregory J, Khrom Michelle, International IBD Genetics Consortium, Ananthakrishnan Ashwin N, Faubion William A, Jabri Bana, Lira Sergio A, Newberry Rodney D, Sandler Robert S, Sartor R Balfour, Xavier Ramnik J, Brant Steven R, Cho Judy H, Duerr Richard H, Lazarev Mark G, Rioux John D, Schumm L Philip, Silverberg Mark S, Zaghiyan Karen, Fleshner Phillip, Melmed Gil Y, Vasiliauskas Eric A, Ha Christina, Rabizadeh Shervin, Syal Gaurav, Bonthala Nirupama N, Ziring David A, Targan Stephan R, Long Millie, McGovern Dermot P B, Michelsen Kathrin S, Brand Stephan
A Pleiotropic Missense Variant in SLC39A8 Is Associated With Crohn's Disease and Human Gut Microbiome Composition
Li D, Devlin B, Sharma Y, Torkvist L, Targan S, Stempak J, Simms L, Regueiro M, Proctor D, Borneman J, Hakonarson H, McGovern D, Braun J, Cho J, Silverberg M, Rioux J, Brant S, Daly M, Xavier R, Milgrom R, Glas J, Halfvarson J, Radford-Smith G, Brand S, D'Amato M, Hui K, Jacobs J, Haritunians T, Achkar J, Niess J, Kugathasan S, Fiocchi C, Dubinsky M, Baidoo L, Aumais G, Ananthakrishnan A, Klei L, Schumm L, Büning C, Duerr R. A Pleiotropic Missense Variant in SLC39A8 Is Associated With Crohn's Disease and Human Gut Microbiome Composition. Gastroenterology 2016; 151:724-32.
Aug 1, 2016A Pleiotropic Missense Variant in SLC39A8 Is Associated With Crohn's Disease and Human Gut Microbiome Composition
Aug 1, 2016Gastroenterology 2016; 151:724-32
Li Dalin, Devlin Bernie, Sharma Yashoda, Torkvist Leif, Targan Stephan R, Stempak Joanne M, Simms Lisa A, Regueiro Miguel, Proctor Deborah D, Borneman James, Hakonarson Hakon, McGovern Dermot P B, Braun Jonathan, Cho Judy H, Silverberg Mark S, Rioux John D, Brant Steven R, Daly Mark, Xavier Ramnik J, Milgrom Raquel, Glas Jürgen, Halfvarson Jonas, Radford-Smith Graham, Brand Stephan, D'Amato Mauro, Hui Ken Y, Jacobs Jonathan P, Haritunians Talin, Achkar Jean-Paul, Niess Jan-Hendrik, Kugathasan Subra, Fiocchi Claudio, Dubinsky Marla, Baidoo Leonard, Aumais Guy, Ananthakrishnan Ashwin, Klei Lambertus, Schumm L Philip, Büning Carsten, Duerr Richard H
Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study
Lees C, van der Meulen-de Jong A, Theatre E, Schreiber S, Satsangi J, Lee J, Lawrance I, Kupcinskas L, Kennedy N, Weersma R, Wilson D, Barrett J, McGovern D, Radford-Smith G, Silverberg M, Mansfield J, Rioux J, Vermeire S, Parkes M, Huang H, Hov J, Halfvarson J, Annese V, Andrews J, Andersen V, Ahmad T, Zeissig S, Schumm L, Jostins L, Boucher G, Brand S, Brant S, Cho J, Hakonarson H, Goyette P, Gearry R, Franke A, Ferguson L, Duerr R, Dubinsky M, Daly M, Cleynen I. Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study. Lancet 2015; 387:156-67.
Oct 18, 2015Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study
Oct 18, 2015Lancet 2015; 387:156-67
Lees Charlie W, van der Meulen-de Jong Andrea E, Theatre Emilie, Schreiber Stephan, Satsangi Jack, Lee James C, Lawrance Ian C, Kupcinskas Limas, Kennedy Nicholas A, Weersma Rinse K, Wilson David C, Barrett Jeffrey C, McGovern Dermot P B, Radford-Smith Graham, Silverberg Mark S, Mansfield John, Rioux John D, Vermeire Severine, Parkes Miles, Huang Hailang, Hov Johannes R, Halfvarson Jonas, Annese Vito, Andrews Jane M, Andersen Vibeke, Ahmad Tariq, Zeissig Sebastian, Schumm L Philip, Jostins Luke, Boucher Gabrielle, Brand Stephan, Brant Steven R, Cho Judy H, Hakonarson Hakon, Goyette Philippe, Gearry Richard B, Franke Andre, Ferguson Lynnette R, Duerr Richard H, Dubinsky Marla, Daly Mark J, Cleynen Isabelle
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
Glas J, Mowat C, Newman W, Panés J, Phillips A, Proctor D, Regueiro M, Russell R, Rutgeerts P, Sanderson J, Sans M, Louis E, Libioulle C, Van Gossum A, Guthery S, Halfvarson J, Verspaget H, Hugot J, Karban A, Laukens D, Lawrance I, Lemann M, Levine A, Seibold F, Steinhart A, Mansfield J, Vermeire S, Duerr R, Silverberg M, Satsangi J, Schreiber S, Cho J, Annese V, Hakonarson H, Daly M, Griffiths A, Kugathasan S, Stokkers P, Torkvist L, Kullak-Ublick G, Wilson D, Walters T, Targan S, Brant S, Rioux J, D'Amato M, Weersma R, Parkes M, Franke A, Ellinghaus D, Festen E, Georges M, Green T, Haritunians T, Jostins L, Latiano A, Mathew C, Montgomery G, Prescott N, Bumpstead S, Bis J, McGovern D, Barrett J, Wang K, Radford-Smith G, Ahmad T, Lees C, Balschun T, Lee J, Roberts R, Anderson C, Raychaudhuri S, Rotter J, Colombel J, Cottone M, Stronati L, Denson T, De Vos M, D'Inca R, Dubinsky M, Edwards C, Florin T, Franchimont D, Cohen A, Büning C, Schumm P, Sharma Y, Simms L, Taylor K, Whiteman D, Wijmenga C, Baldassano R, Barclay M, Bayless T, Brand S, Gearry R. Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat Genet 2010; 42:1118-25.
Dec 1, 2010Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
Dec 1, 2010Nat Genet 2010; 42:1118-25
Glas Jürgen, Mowat Craig, Newman William, Panés Julián, Phillips Anne, Proctor Deborah D, Regueiro Miguel, Russell Richard, Rutgeerts Paul, Sanderson Jeremy, Sans Miquel, Louis Edouard, Libioulle Cecile, Van Gossum Andre, Guthery Stephen L, Halfvarson Jonas, Verspaget Hein W, Hugot Jean-Pierre, Karban Amir, Laukens Debby, Lawrance Ian, Lemann Marc, Levine Arie, Seibold Frank, Steinhart A Hillary, Mansfield John C, Vermeire Severine, Duerr Richard H, Silverberg Mark S, Satsangi Jack, Schreiber Stefan, Cho Judy H, Annese Vito, Hakonarson Hakon, Daly Mark J, Griffiths Anne M, Kugathasan Subra, Stokkers Pieter C F, Torkvist Leif, Kullak-Ublick Gerd, Wilson David, Walters Thomas, Targan Stephan R, Brant Steven R, Rioux John D, D'Amato Mauro, Weersma Rinse K, Parkes Miles, Franke Andre, Ellinghaus David, Festen Eleonora M, Georges Michel, Green Todd, Haritunians Talin, Jostins Luke, Latiano Anna, Mathew Christopher G, Montgomery Grant W, Prescott Natalie J, Bumpstead Suzanne, Bis Joshua C, McGovern Dermot P B, Barrett Jeffrey C, Wang Kai, Radford-Smith Graham L, Ahmad Tariq, Lees Charlie W, Balschun Tobias, Lee James, Roberts Rebecca, Anderson Carl A, Raychaudhuri Soumya, Rotter Jerome I, Colombel Jean-Frederick, Cottone Mario, Stronati Laura, Denson Ted, De Vos Martine, D'Inca Renata, Dubinsky Marla, Edwards Cathryn, Florin Tim, Franchimont Denis, Cohen Albert, Büning Carsten, Schumm Philip, Sharma Yashoda, Simms Lisa A, Taylor Kent D, Whiteman David, Wijmenga Cisca, Baldassano Robert N, Barclay Murray, Bayless Theodore M, Brand Stephan, Gearry Richard