Anca Franzini
Predictive and prognostic value of integrated exon-level expression to approach drug-response and resistance to EGFR-targeted treatment in non-small cell lung cancer
Jan 1, 2015Activating mutations in lung cancer are targeted by a series of molecularly targeted therapies. Patients harboring such mutations can receive significant benefit from these therapies. However a proportion of patients without activating mutations can...
Fundamental Research - Jan 1, 2015 - Dec 31, 2016
Automatically Closed
Project leader: Baty Florent
Members: Franzini Anca, Früh Martin, Jörger Markus, Brutsche Martin
Genome-wide Gene/Exon expression analysis of late stage NSCLC treated by Erlotinib /Bevacizumab: role of tumor-stroma interactions
Feb 1, 2013Genome-wide Gene/Exon expression analysis of late stage NSCLC treated by Erlotinib /Bevacizumab: role of tumor-stroma interactions
Fundamental Research - Feb 1, 2013 - Jun 1, 2015
Completed
Project leader: Baty Florent
Members: Brutsche Martin, Oliver Dürr, Franzini Anca
Systembiologische Untersuchungen zur molekularen Charakterisierung der Mikroumgebung in Lungentumoren
Jul 1, 2012Das Thema des geplanten Forschungsprojekts sind systembiologische Untersuchungen zur molekularen Charakterisierung der Mikroumgebung in Lungentumoren. Lungenkrebs ist eine der häufigsten Todesursachen in den industrialisierten Ländern. Die meisten Pa...
Fundamental Research - Jul 1, 2012 - Jun 30, 2014
Completed
Project leader: Ludewig Burkhard, Brutsche Martin
Members: Franzini Anca, Tarantino Ignazio
Systems biology approach to moleculary characterize the lung cancer microenvironment
Jul 1, 2012Tumor cells display distinct genetic alterations that permit their unrestricted growth. In contrast, stromal cells that provide the growth scaffold and nutrients for the tumor, most likely exhibit universal signatures that determine their function. T...
Fundamental Research - Jul 1, 2012 - Jun 30, 2014
Completed
Project leader: Ludewig Burkhard
Members: Franzini Anca, Bocharov Gennady