A Study to Learn About the Safety of BIIB080 and Whether it Can Improve Symptoms of Participants With Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild AD Dementia Between 50 to 80 Years of Age

Clinical Studies - Mar 1, 2024 - Dec 31, 2026

Ongoing

Project leader: Felbecker Ansgar
Members: Göhl-Freyn Kristina

Dementia is a clinical syndrome defined by a progressive cognitive decline interfering with a person's daily life and activities which is caused by a group of heterogenous neurodegenerative and neurovascular diseases which often overlap. Since patho...

Clinical Studies - Mar 1, 2024 - Dec 31, 2040

Ongoing

Project leader: Schneider Thomas, Felbecker Ansgar
Members: Göhl-Freyn Kristina, Schilg-Hafer Lenka

The Inflammatory Neuropathy Consortium Base (INCbase) is an international registry for CIDP patients led by an international collaboration of CIDP experts. INCbase provides a state of the art modular research database that members may use to collect...

Fundamental Research - Dec 15, 2021 - Dec 15, 2025

Ongoing

Members: Felbecker Ansgar, Leupold Daniela

This prospective observational pilot study examines cognitive function 1 year after SARS-Cov-2 disease. Study population consists of formerly hospitalized non-ventilated COVID-19 patients (nvCOVID) and ventilated patients with COVID-19-ARDS (cARDS) t...

Clinical Studies - Oct 19, 2021 - Dec 31, 2022

Automatically Closed

Project leader: Göhl-Freyn Kristina, Felbecker Ansgar
Members: Albrich Werner, Schmid Dagmar, Kleger Gian-Reto, Schrag Claudia, Pietsch Urs

A Research Study Investigating Semaglutide in People With Early Alzheimer's Disease (EVOKE) This study is done to find out whether semaglutide has a positive effect on early Alzheimer's disease. Participants will either get semaglutide or placebo - w...

Clinical Studies - Sep 30, 2021 - Dec 31, 2025

Ongoing

Project leader: Felbecker Ansgar

Clinical Studies - May 12, 2021 - Sep 15, 2022

Completed

Project leader: Felbecker Ansgar

In dem geförderten Kooperationsprojekt “Development of a non-invasive screening system for the early detection of mild cognitive impairments in older adults” wird untersucht, ob ein multimodales nicht-invasives Testsystem geeignet ist, um frühe Stadi...

Clinical Studies - Nov 1, 2020 - Jul 1, 2021

Automatically Closed

Project leader: Felbecker Ansgar
Members: Schneider Thomas

Outcome of patients with critical Covid-19 varies. We study risk of and predictors for poor outcome in adult patients with Covid-19 admitted to ICU in a multicenter study. In addition, we assess the prevalence of, risk factors for and mechanisms invo...

Clinical Studies - Aug 1, 2020 - Aug 31, 2022

Automatically Closed

Project leader: Albrich Werner
Members: Von Mering Christian, O'Mahony Liam, Cerny Andreas, Suh Noémie, El Baz Yassir, Dietrich Tobias, Fischer Tim, Felbecker Ansgar, Göhl-Freyn Kristina, Germann Nicolas, Schmid Dagmar, Kahlert Christian, Frischknecht Manuel, Filipovic Miodrag, Brutsche Martin, Pietsch Urs, Kleger Gian-Reto, Bochud Pierre-Yves

Background: The key neuropathological feature of Alzheimer disease (AD) is the accumulation of extracellular β-amyloid (Aβ) plaques in the brain which begins long before clinical signs of dementia. Immunotherapies targeting Aβ may prevent Aβ accumula...

Fundamental Research - Jun 1, 2020 - May 30, 2022

Automatically Closed

Project leader: Felbecker Ansgar
Members: Schneider Thomas, Nirmjaraj Peter

Multizentrische Therapiestudie zur Anwednung von Desmoteplase

Clinical Studies - Mar 12, 2010 - Dec 31, 2012

Aborted

Project leader: Weder Bruno, Kägi Georg
Members: Hundsberger Thomas, Felbecker Ansgar, Hägele-Link Stefan, Galovic Marian, Leupold Daniela