Unit
Medizinische Onkologie und Hämatologie
ONKO · Dept. I
Antibodies as biomarker candidates for response and survival to checkpoint inhibitors in melanoma patients
Fässler M, Jörger M, Recher M, Risch L, Güsewell S, Risch M, Speiser D, Ludewig B, Levesque M, Dummer R, Siano M, Krolik M, Diem S, Mangana J, Hasan Ali O, Berner F, Bomze D, Ring S, Niederer R, Gil Cruz C, Pérez Shibayama C, Flatz L. Antibodies as biomarker candidates for response and survival to checkpoint inhibitors in melanoma patients. J Immunother Cancer 2019; 7:50.
Feb 20, 2019Antibodies as biomarker candidates for response and survival to checkpoint inhibitors in melanoma patients
Feb 20, 2019J Immunother Cancer 2019; 7:50
Fässler Mirjam, Jörger Markus, Recher Mike, Risch Lorenz, Güsewell Sabine, Risch Martin, Speiser Daniel E, Ludewig Burkhard, Levesque Mitchell P, Dummer Reinhard, Siano Marco, Krolik Michal, Diem Stefan, Mangana Joanna, Hasan Ali Omar, Berner Fiamma, Bomze David, Ring Sandra, Niederer Rebekka, Gil Cruz Cristina, Pérez Shibayama Christian Ivan, Flatz Lukas
Patterns of progression on osimertinib in EGFR T790M positive NSCLC: A Swiss cohort study
Schmid S, Jochum W, Demmer I, Foerbs D, Janthur W, Wannesson L, Rothschild S, Pless M, Gautschi O, Britschgi C, Aeppli S, Klingbiel D, Früh M. Patterns of progression on osimertinib in EGFR T790M positive NSCLC: A Swiss cohort study. Lung Cancer 2019; 130:149-155.
Feb 19, 2019Patterns of progression on osimertinib in EGFR T790M positive NSCLC: A Swiss cohort study
Feb 19, 2019Lung Cancer 2019; 130:149-155
Schmid Sabine, Jochum Wolfram, Demmer I, Foerbs D, Janthur W, Wannesson L, Rothschild S, Pless M, Gautschi O, Britschgi C, Aeppli Stefanie, Klingbiel D, Früh Martin
Replacement of miR-155 Elicits Tumor Suppressive Activity and Antagonizes Bortezomib Resistance in Multiple Myeloma
Amodio N, Tagliaferri P, Neri A, Driessen C, Rossi M, Ronchetti D, Caracciolo D, Federico C, Agosti V, Botta C, Gallo Cantafio M, Tassone P. Replacement of miR-155 Elicits Tumor Suppressive Activity and Antagonizes Bortezomib Resistance in Multiple Myeloma. Cancers (Basel) 2019; 11
Feb 18, 2019Replacement of miR-155 Elicits Tumor Suppressive Activity and Antagonizes Bortezomib Resistance in Multiple Myeloma
Feb 18, 2019Cancers (Basel) 2019; 11
Amodio Nicola, Tagliaferri Pierosandro, Neri Antonino, Driessen Christoph, Rossi Marco, Ronchetti Domenica, Caracciolo Daniele, Federico Cinzia, Agosti Valter, Botta Cirino, Gallo Cantafio Maria Eugenia, Tassone Pierfrancesco
Correction: HER2-Overexpressing Breast Cancers Amplify FGFR Signaling upon Acquisition of Resistance to Dual Therapeutic Blockade of HER2
Hanker A, Castellino S, Joensuu H, Huober J, Brase J, Majjaj S, Brohée S, Venet D, Brown D, Baselga J, Piccart M, Sotiriou C, Groseclose M, Becker J, Garrett J, Estrada M, Moore P, Ericsson P, Koch J, Langley E, Singh S, Kim P, Frampton G, Sanford E, Owens P, Arteaga C. Correction: HER2-Overexpressing Breast Cancers Amplify FGFR Signaling upon Acquisition of Resistance to Dual Therapeutic Blockade of HER2. Clin Cancer Res 2019; 25:1434.
Feb 15, 2019Correction: HER2-Overexpressing Breast Cancers Amplify FGFR Signaling upon Acquisition of Resistance to Dual Therapeutic Blockade of HER2
Feb 15, 2019Clin Cancer Res 2019; 25:1434
Hanker Ariella B, Castellino Stephen, Joensuu Heikki, Huober Jens, Brase Jan C, Majjaj Samira, Brohée Sylvain, Venet David, Brown David, Baselga José, Piccart Martine, Sotiriou Christos, Groseclose M Reid, Becker Jennifer, Garrett Joan T, Estrada Mónica Valeria, Moore Preston D, Ericsson Paula González, Koch James P, Langley Emma, Singh Sharat, Kim Phillip S, Frampton Garrett M, Sanford Eric, Owens Philip, Arteaga Carlos L
A Variant of a Killer Cell Immunoglobulin-like Receptor Is Associated with Resistance to PD-1 Blockade in Lung Cancer
Trefny M, Savic S, Jermann P, Alborelli I, Schaub S, Stenner F, Früh M, Trajanoski Z, Flatz L, Mertz K, Zippelius A, Geier F, Thommen D, Rothschild S, Uhlenbrock F, Rieder D, Kasenda B, Stanczak M, Berner F, Kashyap A, Kaiser M, Herzig P, Poechtrager S, Läubli H. A Variant of a Killer Cell Immunoglobulin-like Receptor Is Associated with Resistance to PD-1 Blockade in Lung Cancer. Clin Cancer Res 2019; 25:3026-3034.
Feb 14, 2019A Variant of a Killer Cell Immunoglobulin-like Receptor Is Associated with Resistance to PD-1 Blockade in Lung Cancer
Feb 14, 2019Clin Cancer Res 2019; 25:3026-3034
Trefny Marcel P, Savic Spasenija, Jermann Philip, Alborelli Ilaria, Schaub Stefan, Stenner Frank, Früh Martin, Trajanoski Zlatko, Flatz Lukas, Mertz Kirsten D, Zippelius Alfred, Geier Florian, Thommen Daniela S, Rothschild Sacha I, Uhlenbrock Franziska, Rieder Dietmar, Kasenda Benjamin, Stanczak Michal A, Berner Fiamma, Kashyap Abhishek S, Kaiser Monika, Herzig Petra, Poechtrager Severin, Läubli Heinz
Phase Ib evaluation of a self-adjuvanted protamine formulated mRNA-based active cancer immunotherapy, BI1361849 (CV9202), combined with local radiation treatment in patients with stage IV non-small cell lung cancer
Papachristofilou A, Kallen K, Fotin-Mleczek M, Schröder A, Scheel B, Muth A, Seibel T, Stosnach C, Doener F, Hong H, Koch S, Gnad-Vogt U, Griesinger F, Geißler M, Bischoff H, Hipp M, Klinkhardt U, Früh M, Sebastian M, Weiss C, Pless M, Cathomas R, Hilbe W, Pall G, Wehler T, Alt J, Zippelius A. Phase Ib evaluation of a self-adjuvanted protamine formulated mRNA-based active cancer immunotherapy, BI1361849 (CV9202), combined with local radiation treatment in patients with stage IV non-small cell lung cancer. J Immunother Cancer 2019; 7:38.
Feb 8, 2019Phase Ib evaluation of a self-adjuvanted protamine formulated mRNA-based active cancer immunotherapy, BI1361849 (CV9202), combined with local radiation treatment in patients with stage IV non-small cell lung cancer
Feb 8, 2019J Immunother Cancer 2019; 7:38
Papachristofilou Alexandros, Kallen Karl-Josef, Fotin-Mleczek Mariola, Schröder Andreas, Scheel Birgit, Muth Anke, Seibel Tobias, Stosnach Claudia, Doener Fatma, Hong Henoch S, Koch Sven D, Gnad-Vogt Ulrike, Griesinger Frank, Geißler Michael, Bischoff Helge, Hipp Madeleine M, Klinkhardt Ute, Früh Martin, Sebastian Martin, Weiss Christian, Pless Miklos, Cathomas Richard, Hilbe Wolfgang, Pall Georg, Wehler Thomas, Alt Jürgen, Zippelius Alfred
Structure-Based Design of Inhibitors Selective for Human Proteasome β2c or β2i Subunits
Xin B, Groll M, van der Marel G, Driessen C, Florea B, Kisselev A, Weyburne E, Janssens M, Du Y, Espinal C, Maurits E, Heinemeyer W, de Bruin G, Huber E, Overkleeft H. Structure-Based Design of Inhibitors Selective for Human Proteasome β2c or β2i Subunits. J Med Chem 2019; 62:1626-1642.
Feb 5, 2019Structure-Based Design of Inhibitors Selective for Human Proteasome β2c or β2i Subunits
Feb 5, 2019J Med Chem 2019; 62:1626-1642
Xin Bo-Tao, Groll Michael, van der Marel Gijsbert A, Driessen Christoph, Florea Bogdan I, Kisselev Alexei F, Weyburne Emily S, Janssens Marissa, Du Yimeng, Espinal Christofer, Maurits Elmer, Heinemeyer Wolfgang, de Bruin Gerjan, Huber Eva M, Overkleeft Herman S
Prophylactic cranial irradiation in stage IV small cell lung cancer: Selection of patients amongst European IASLC and ESTRO experts
Putora P, Novello S, O'Brien M, Paz Ares L, Peeters S, Pöttgen C, Ramella S, Reck M, Slotman B, Troost E, Van Houtte P, Westeel V, Widder J, Mornex F, Nestle U, McDonald F, Glatzer M, Belderbos J, Besse B, Blackhall F, Califano R, Cappuzzo F, de Marinis F, Dziadziuszko R, Felip E, Faivre-Finn C, Früh M, Garrido P, Le Pechoux C, De Ruysscher D. Prophylactic cranial irradiation in stage IV small cell lung cancer: Selection of patients amongst European IASLC and ESTRO experts. Radiother Oncol 2019; 133:163-166.
Jan 31, 2019Prophylactic cranial irradiation in stage IV small cell lung cancer: Selection of patients amongst European IASLC and ESTRO experts
Jan 31, 2019Radiother Oncol 2019; 133:163-166
Putora Paul Martin, Novello Silvia, O'Brien Mary, Paz Ares Luis, Peeters Stephanie, Pöttgen Christoph, Ramella Sara, Reck Martin, Slotman Ben, Troost Esther G C, Van Houtte Paul, Westeel Virginie, Widder Joachim, Mornex Francoise, Nestle Ursula, McDonald Fiona, Glatzer Markus, Belderbos Jose, Besse Benjamin, Blackhall Fiona, Califano Raffaele, Cappuzzo Federico, de Marinis Filippo, Dziadziuszko Rafal, Felip Enriqueta, Faivre-Finn Corinne, Früh Martin, Garrido Pilar, Le Pechoux Cecila, De Ruysscher Dirk
Prognostic impact of polypharmacy and drug interactions in patients with advanced cancer
Hoemme A, Driessen C, Früh M, Thürlimann B, Wälti T, von Kameke A, Lehner C, Strasser F, Krähenbühl S, Haschke M, Barth H, Jörger M. Prognostic impact of polypharmacy and drug interactions in patients with advanced cancer. Cancer Chemother Pharmacol 2019; 83:763-774.
Jan 25, 2019Prognostic impact of polypharmacy and drug interactions in patients with advanced cancer
Jan 25, 2019Cancer Chemother Pharmacol 2019; 83:763-774
Hoemme Alexander, Driessen Christoph, Früh Martin, Thürlimann Beat, Wälti Thomas, von Kameke Alexander, Lehner Claudia, Strasser Florian, Krähenbühl Stephan, Haschke Manuel, Barth Holger, Jörger Markus
Cost-Efficient and Easy to Perform PCR-Based Assay to Identify Met Exon 14 Skipping in Formalin-Fixed Paraffin-Embedded (FFPE) Non-Small Cell Lung Cancer (NSCLC) Samples
O'Brien O, Gray S, Jörger M, Jochum W, Fabre A, Cuffe S, Nicholson S, Leonard N, Geoghegan O, O'Brien C, Wright M, Finn S. Cost-Efficient and Easy to Perform PCR-Based Assay to Identify Met Exon 14 Skipping in Formalin-Fixed Paraffin-Embedded (FFPE) Non-Small Cell Lung Cancer (NSCLC) Samples. Diagnostics (Basel) 2019; 9
Jan 18, 2019Cost-Efficient and Easy to Perform PCR-Based Assay to Identify Met Exon 14 Skipping in Formalin-Fixed Paraffin-Embedded (FFPE) Non-Small Cell Lung Cancer (NSCLC) Samples
Jan 18, 2019Diagnostics (Basel) 2019; 9
O'Brien Odharnaith, Gray Steven G, Jörger Markus, Jochum Wolfram, Fabre Aurelie, Cuffe Sinead, Nicholson Siobhan, Leonard Niamh, Geoghegan Orla, O'Brien Cathal, Wright Mark C, Finn Stephen P
Tumor autophagy is associated with survival outcomes in patients with resected non-small cell lung cancer
Überall I, Gachechiladze M, Jörger M, Anděl J, Smičková P, Kolek V, Grygárková I, Škarda J. Tumor autophagy is associated with survival outcomes in patients with resected non-small cell lung cancer. Lung Cancer 2019; 129:85-91.
Jan 8, 2019Tumor autophagy is associated with survival outcomes in patients with resected non-small cell lung cancer
Jan 8, 2019Lung Cancer 2019; 129:85-91
Überall Ivo, Gachechiladze Mariam, Jörger Markus, Anděl Josef, Smičková Petra, Kolek Vítězslav, Grygárková Ivona, Škarda Josef
Radium-223 in asymptomatic patients with castration-resistant prostate cancer and bone metastases treated in an international early access program
Heidenreich A, Nilsson S, Seger M, Reeves J, Miller K, Wirth M, Carles J, O'Sullivan J, Keizman D, Heinrich D, Gillessen Sommer S, Saad F. Radium-223 in asymptomatic patients with castration-resistant prostate cancer and bone metastases treated in an international early access program. BMC cancer 2019; 19:12.
Jan 7, 2019Radium-223 in asymptomatic patients with castration-resistant prostate cancer and bone metastases treated in an international early access program
Jan 7, 2019BMC cancer 2019; 19:12
Heidenreich Axel, Nilsson Sten, Seger Monica, Reeves John, Miller Kurt, Wirth Manfred, Carles Joan, O'Sullivan Joe M, Keizman Daniel, Heinrich Daniel, Gillessen Sommer Silke, Saad Fred
Impact of Older Age on the Exposure of Paclitaxel: a Population Pharmacokinetic Study
Crombag M, Beijnen J, Mathijssen R, van Erp N, Dorlo T, Schellens J, Jörger M, Wijngaard S, Koolen S, de Vries Schultink A, Huitema A. Impact of Older Age on the Exposure of Paclitaxel: a Population Pharmacokinetic Study. Pharm Res 2019; 36:33.
Jan 7, 2019Impact of Older Age on the Exposure of Paclitaxel: a Population Pharmacokinetic Study
Jan 7, 2019Pharm Res 2019; 36:33
Crombag Marie-Rose B S, Beijnen Jos H, Mathijssen Ron H J, van Erp Nielka P, Dorlo Thomas P C, Schellens Jan H M, Jörger Markus, Wijngaard Sophie, Koolen Stijn L W, de Vries Schultink Aurelia H M, Huitema Alwin D R
and Prognosis in mCRPC Survival: Biology or Coincidence?
Rebello R, Oing C, Gillessen Sommer S, Bristow R. and Prognosis in mCRPC Survival: Biology or Coincidence?. Clin Cancer Res 2019; 25:1699-1701.
Jan 4, 2019and Prognosis in mCRPC Survival: Biology or Coincidence?
Jan 4, 2019Clin Cancer Res 2019; 25:1699-1701
Rebello Richard J, Oing Christoph, Gillessen Sommer Silke, Bristow Robert G
Impact of Addition of Metformin to Abiraterone in Metastatic Castration-Resistant Prostate Cancer Patients With Disease Progressing While Receiving Abiraterone Treatment (MetAb-Pro): Phase 2 Pilot Study
Mark M, Strebel R, Manetsch G, Pollak M, von Moos R, Gillessen Sommer S, Rothermundt C, Winterhalder R, Mey U, Klingbiel D, Cathomas R. Impact of Addition of Metformin to Abiraterone in Metastatic Castration-Resistant Prostate Cancer Patients With Disease Progressing While Receiving Abiraterone Treatment (MetAb-Pro): Phase 2 Pilot Study. Clin Genitourin Cancer 2019
Jan 2, 2019Impact of Addition of Metformin to Abiraterone in Metastatic Castration-Resistant Prostate Cancer Patients With Disease Progressing While Receiving Abiraterone Treatment (MetAb-Pro): Phase 2 Pilot Study
Jan 2, 2019Clin Genitourin Cancer 2019
Mark Michael, Strebel Räto, Manetsch Gabriela, Pollak Michael, von Moos Roger, Gillessen Sommer Silke, Rothermundt Christian, Winterhalder Ralph, Mey Ulrich, Klingbiel Dirk, Cathomas Richard
The Advanced Prostate Cancer Consensus on a regional level - what can we learn?
Omlin A, Gillessen Sommer S. The Advanced Prostate Cancer Consensus on a regional level - what can we learn?. BJU Int 2019; 123:3-4.
Jan 1, 2019The Advanced Prostate Cancer Consensus on a regional level - what can we learn?
Jan 1, 2019BJU Int 2019; 123:3-4
Omlin Aurelius, Gillessen Sommer Silke
Renal cell carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up†
Escudier B, Horwich A, Gillessen Sommer S, Grünwald V, Khoo V, Bex A, Rioux-Leclercq N, Schmidinger M, Porta C, ESMO Guidelines Committee. Renal cell carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up†. Ann Oncol 2019; 30:706-720.
Jan 1, 2019Renal cell carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up†
Jan 1, 2019Ann Oncol 2019; 30:706-720
Escudier B, Horwich A, Gillessen Sommer Silke, Grünwald V, Khoo V, Bex A, Rioux-Leclercq N, Schmidinger M, Porta C, ESMO Guidelines Committee
A randomised phase II study investigating durvalumab in addition to an anthracycline taxane-based neoadjuvant therapy in early triple-negative breast cancer: clinical results and biomarker analysis of GeparNuevo study
Loibl S, Schmitt W, von Minckwitz G, Thomalla J, Kümmel S, Rautenberg B, Fasching P, Weber K, Rhiem K, Denkert C, Jackisch C, Rezai M, Engels K, Untch M, Burchardi N, Huober J, Sinn B, Blohmer J, Grischke E, Furlanetto J, Tesch H, Hanusch C, Schneeweiss A. A randomised phase II study investigating durvalumab in addition to an anthracycline taxane-based neoadjuvant therapy in early triple-negative breast cancer: clinical results and biomarker analysis of GeparNuevo study. Ann Oncol 2019; 30:1279-1288.
Jan 1, 2019A randomised phase II study investigating durvalumab in addition to an anthracycline taxane-based neoadjuvant therapy in early triple-negative breast cancer: clinical results and biomarker analysis of GeparNuevo study
Jan 1, 2019Ann Oncol 2019; 30:1279-1288
Loibl S, Schmitt W D, von Minckwitz G, Thomalla J, Kümmel S, Rautenberg B, Fasching P A, Weber K, Rhiem K, Denkert C, Jackisch C, Rezai M, Engels K, Untch M, Burchardi N, Huober Jens, Sinn B V, Blohmer J-U, Grischke E-M, Furlanetto J, Tesch H, Hanusch C, Schneeweiss A
Lung cancer and smoking trends in the young in Switzerland: a study based on data of the National Institute for Cancer Epidemiology and Registration and of the Swiss Health Surveys
Mousavi S, Schmid S, Cerny T, Früh M. Lung cancer and smoking trends in the young in Switzerland: a study based on data of the National Institute for Cancer Epidemiology and Registration and of the Swiss Health Surveys. Swiss Med Wkly 2018; 148:w14708.
Dec 30, 2018Lung cancer and smoking trends in the young in Switzerland: a study based on data of the National Institute for Cancer Epidemiology and Registration and of the Swiss Health Surveys
Dec 30, 2018Swiss Med Wkly 2018; 148:w14708
Mousavi Seyed Mohsen, Schmid Sabine, Cerny Thomas, Früh Martin
Therapy Landscape in Patients with Metastatic HER2-Positive Breast Cancer: Data from the PRAEGNANT Real-World Breast Cancer Registry
Lux M, Wimberger P, Hielscher C, Geberth M, Abenhardt W, Kurbacher C, Wuerstlein R, Thomssen C, Untch M, Fasching P, Janni W, Fehm T, Wallwiener D, Schneeweiss A, Belleville E, Beckmann M, Müller V, Nabieva N, Hartkopf A, Huober J, Volz B, Taran F, Overkamp F, Kolberg H, Hadji P, Tesch H, Häberle L, Ettl J, Luftner D, Wallwiener M, Brucker S. Therapy Landscape in Patients with Metastatic HER2-Positive Breast Cancer: Data from the PRAEGNANT Real-World Breast Cancer Registry. Cancers (Basel) 2018; 11
Dec 21, 2018Therapy Landscape in Patients with Metastatic HER2-Positive Breast Cancer: Data from the PRAEGNANT Real-World Breast Cancer Registry
Dec 21, 2018Cancers (Basel) 2018; 11
Lux Michael P, Wimberger Pauline, Hielscher Carsten, Geberth Matthias, Abenhardt Wolfgang, Kurbacher Christian, Wuerstlein Rachel, Thomssen Christoph, Untch Michael, Fasching Peter A, Janni Wolfgang, Fehm Tanja N, Wallwiener Diethelm, Schneeweiss Andreas, Belleville Erik, Beckmann Matthias W, Müller Volkmar, Nabieva Naiba, Hartkopf Andreas D, Huober Jens, Volz Bernhard, Taran Florin-Andrei, Overkamp Friedrich, Kolberg Hans-Christian, Hadji Peyman, Tesch Hans, Häberle Lothar, Ettl Johannes, Luftner Diana, Wallwiener Markus, Brucker Sara Y