Unit
Institute of Immunobiology
IMMBIO · Management
Replication of human coronaviruses SARS-CoV, HCoV-NL63 and HCoV-229E is inhibited by the drug FK506
Carbajo-Lozoya J, Müller M, Kallies S, Thiel V, Drosten C, von Brunn A. Replication of human coronaviruses SARS-CoV, HCoV-NL63 and HCoV-229E is inhibited by the drug FK506. Virus Res 2012; 165:112-7.
Feb 10, 2012Replication of human coronaviruses SARS-CoV, HCoV-NL63 and HCoV-229E is inhibited by the drug FK506
Feb 10, 2012Virus Res 2012; 165:112-7
Carbajo-Lozoya Javier, Müller Marcel A, Kallies Stephan, Thiel Volker, Drosten Christian, von Brunn Albrecht
Plasmacytoid dendritic cells control T-cell response to chronic viral infection.
Cervantes-Barragan L, Lewis K, Firner S, Thiel V, Hugues S, Reith W, Ludewig B, Reizis B. Plasmacytoid dendritic cells control T-cell response to chronic viral infection. Proc Natl Acad Sci U S A 2012; 109:3012-7.
Feb 6, 2012Plasmacytoid dendritic cells control T-cell response to chronic viral infection.
Feb 6, 2012Proc Natl Acad Sci U S A 2012; 109:3012-7
Cervantes-Barragan Luisa, Lewis Kanako L, Firner Sonja, Thiel Volker, Hugues Stephanie, Reith Walter, Ludewig Burkhard, Reizis Boris
T helper cell- and CD40-dependent germline IgM prevents chronic virus-induced demyelinating disease.
Gil-Cruz C, Perez-Shibayama C, Firner S, Waisman A, Bechmann I, Thiel V, Cervantes-Barragan L, Ludewig B. T helper cell- and CD40-dependent germline IgM prevents chronic virus-induced demyelinating disease. Proc Natl Acad Sci U S A 2012; 109:1233-8.
Jan 9, 2012T helper cell- and CD40-dependent germline IgM prevents chronic virus-induced demyelinating disease.
Jan 9, 2012Proc Natl Acad Sci U S A 2012; 109:1233-8
Gil-Cruz Cristina, Perez-Shibayama Christian, Firner Sonja, Waisman Ari, Bechmann Ingo, Thiel Volker, Cervantes-Barragan Luisa, Ludewig Burkhard
The dominance of human coronavirus OC43 and NL63 infections in infants
Dijkman R, Jebbink M, Gaunt E, Rossen J, Templeton K, Kuijpers T, van der Hoek L. The dominance of human coronavirus OC43 and NL63 infections in infants. J Clin Virol 2011; 53:135-9.
Dec 19, 2011The dominance of human coronavirus OC43 and NL63 infections in infants
Dec 19, 2011J Clin Virol 2011; 53:135-9
Dijkman Ronald, Jebbink Maarten F, Gaunt Eleanor, Rossen John W A, Templeton Kate E, Kuijpers Taco W, van der Hoek Lia
CD169(+) macrophages take the bullet
Ludewig B, Cervantes-Barragan L. CD169(+) macrophages take the bullet. Nat Immunol 2011; 13:13-4.
Dec 16, 2011CD169(+) macrophages take the bullet
Dec 16, 2011Nat Immunol 2011; 13:13-4
Ludewig Burkhard, Cervantes-Barragan Luisa
The SARS-Coronavirus-Host Interactome: Identification of Cyclophilins as Target for Pan-Coronavirus Inhibitors
Pfefferle S, Hilgenfeld R, Schwarz F, Zimmer R, Steffen I, Weber F, Thiel V, Herrler G, Thiel H, Schwegmann-Weßels C, Pöhlmann S, Haas J, Drosten C, Pumpor K, Züst R, Schöpf J, Kögl M, Friedel C, Müller M, Carbajo-Lozoya J, Stellberger T, von Dall'armi E, Herzog P, Kallies S, Niemeyer D, Ditt V, Kuri T, von Brunn A. The SARS-Coronavirus-Host Interactome: Identification of Cyclophilins as Target for Pan-Coronavirus Inhibitors. PLoS Pathog 2011; 7:e1002331.
Oct 27, 2011The SARS-Coronavirus-Host Interactome: Identification of Cyclophilins as Target for Pan-Coronavirus Inhibitors
Oct 27, 2011PLoS Pathog 2011; 7:e1002331
Pfefferle Susanne, Hilgenfeld Rolf, Schwarz Frank, Zimmer Ralf, Steffen Imke, Weber Friedemann, Thiel Volker, Herrler Georg, Thiel Heinz-Jürgen, Schwegmann-Weßels Christel, Pöhlmann Stefan, Haas Jürgen, Drosten Christian, Pumpor Ksenia, Züst Roland, Schöpf Julia, Kögl Manfred, Friedel Caroline C, Müller Marcel A, Carbajo-Lozoya Javier, Stellberger Thorsten, von Dall'armi Ekatarina, Herzog Petra, Kallies Stefan, Niemeyer Daniela, Ditt Vanessa, Kuri Thomas, von Brunn Albrecht
A novel bacterial artificial chromosome-transgenic podoplanin-cre mouse targets lymphoid organ stromal cells in vivo.
Onder L, Scandella E, Chai Q, Firner S, Mayer C, Sparwasser T, Thiel V, Rülicke T, Ludewig B. A novel bacterial artificial chromosome-transgenic podoplanin-cre mouse targets lymphoid organ stromal cells in vivo. Front Immunol 2011; 2:50.
Oct 12, 2011A novel bacterial artificial chromosome-transgenic podoplanin-cre mouse targets lymphoid organ stromal cells in vivo.
Oct 12, 2011Front Immunol 2011; 2:50
Onder Lucas, Scandella Elke, Chai Qian, Firner Sonja, Mayer Christian T, Sparwasser Tim, Thiel Volker, Rülicke Thomas, Ludewig Burkhard
Simulation of the interferon-mediated protective field in lymphoid organs with their spatial and functional organization taken into consideration
Bocharov G, Danilov A, Vassilevski Y, Marchuk G, Chereshnev V, Ludewig B. Simulation of the interferon-mediated protective field in lymphoid organs with their spatial and functional organization taken into consideration. Dokl Biol Sci 2011; 439:194-6.
Sep 28, 2011Simulation of the interferon-mediated protective field in lymphoid organs with their spatial and functional organization taken into consideration
Sep 28, 2011Dokl Biol Sci 2011; 439:194-6
Bocharov G A, Danilov A A, Vassilevski Yu V, Marchuk G I, Chereshnev V A, Ludewig Burkhard
Cyclosporin A inhibits the replication of diverse coronaviruses
de Wilde A, Zevenhoven-Dobbe J, van der Meer Y, Thiel V, Narayanan K, Makino S, Snijder E, van Hemert M. Cyclosporin A inhibits the replication of diverse coronaviruses. J Gen Virol 2011; 92:2542-8.
Jul 13, 2011Cyclosporin A inhibits the replication of diverse coronaviruses
Jul 13, 2011J Gen Virol 2011; 92:2542-8
de Wilde Adriaan H, Zevenhoven-Dobbe Jessika C, van der Meer Yvonne, Thiel Volker, Narayanan Krishna, Makino Shinji, Snijder Eric J, van Hemert Martijn J
CD31 is required on CD4+ T cells to promote T cell survival during Salmonella infection
Ross E, Buckley C, MacLennan I, Watson S, Khan M, Henderson I, López-Macías C, Gil Cruz C, Hitchcock J, Abhyankar N, Charlesworth J, Hussain K, Marshall J, Bobat S, Flores-Langarica A, Coughlan R, Cunningham A. CD31 is required on CD4+ T cells to promote T cell survival during Salmonella infection. J Immunol 2011; 187:1553-65.
Jul 6, 2011CD31 is required on CD4+ T cells to promote T cell survival during Salmonella infection
Jul 6, 2011J Immunol 2011; 187:1553-65
Ross Ewan A, Buckley Christopher D, MacLennan Ian C M, Watson Steve P, Khan Mahmood, Henderson Ian R, López-Macías Constantino, Gil Cruz Cristina, Hitchcock Jessica, Abhyankar Nikita, Charlesworth James, Hussain Khiyam, Marshall Jennifer L, Bobat Saeeda, Flores-Langarica Adriana, Coughlan Ruth E, Cunningham Adam F
Subversion of innate and adaptive immune activation induced by structurally modified lipopolysaccharide from Salmonella typhimurium
Pastelin-Palacios R, Isibasi A, Gunn J, Bonifaz L, Alpuche-Aranda C, Becker I, García-Zepeda E, Cunningham A, Ludewig B, Arriaga-Pizano L, Cervantes-Barragan L, Moreno-Eutimio M, Pérez Shibayama C, Gil Cruz C, López-Macías C. Subversion of innate and adaptive immune activation induced by structurally modified lipopolysaccharide from Salmonella typhimurium. Immunology 2011; 133:469-81.
Jun 2, 2011Subversion of innate and adaptive immune activation induced by structurally modified lipopolysaccharide from Salmonella typhimurium
Jun 2, 2011Immunology 2011; 133:469-81
Pastelin-Palacios Rodolfo, Isibasi Armando, Gunn John S, Bonifaz Laura, Alpuche-Aranda Celia, Becker Ingeborg, García-Zepeda Eduardo A, Cunningham Adam F, Ludewig Burkhard, Arriaga-Pizano Lourdes, Cervantes-Barragan Luisa, Moreno-Eutimio Mario A, Pérez Shibayama Christian Ivan, Gil Cruz Cristina, López-Macías Constantino
Soluble flagellin, FliC, induces an Ag-specific Th2 response, yet promotes T-bet-regulated Th1 clearance of Salmonella typhimurium infection
Bobat S, MacLennan I, Alexander J, Henderson I, López-Macías C, Dougan G, Chamberlain J, Chester R, Gaspal F, Letran S, Leyton D, Serre K, Gil Cruz C, Goodall M, Kingsley R, Marshall J, Hitchcock J, Flores-Langarica A, Cunningham A. Soluble flagellin, FliC, induces an Ag-specific Th2 response, yet promotes T-bet-regulated Th1 clearance of Salmonella typhimurium infection. Eur J Immunol 2011; 41:1606-18.
May 10, 2011Soluble flagellin, FliC, induces an Ag-specific Th2 response, yet promotes T-bet-regulated Th1 clearance of Salmonella typhimurium infection
May 10, 2011Eur J Immunol 2011; 41:1606-18
Bobat Saeeda, MacLennan Ian C M, Alexander James, Henderson Ian R, López-Macías Constantino, Dougan Gordon, Chamberlain Jayne L, Chester Rebecca, Gaspal Fabrina, Letran Shirdi E, Leyton Denisse L, Serre Karine, Gil Cruz Cristina, Goodall Margaret, Kingsley Robert A, Marshall Jennifer L, Hitchcock Jessica, Flores-Langarica Adriana, Cunningham Adam F
The ADP-ribose-1''-monophosphatase domains of severe acute respiratory syndrome coronavirus and human coronavirus 229E mediate resistance to antiviral interferon responses
Kuri T, Ziebuhr J, Thiel V, Siddell S, Davidson A, Snijder E, Züst R, Putics A, Eriksson K, Weber F. The ADP-ribose-1''-monophosphatase domains of severe acute respiratory syndrome coronavirus and human coronavirus 229E mediate resistance to antiviral interferon responses. J Gen Virol 2011; 92:1899-905.
Apr 27, 2011The ADP-ribose-1''-monophosphatase domains of severe acute respiratory syndrome coronavirus and human coronavirus 229E mediate resistance to antiviral interferon responses
Apr 27, 2011J Gen Virol 2011; 92:1899-905
Kuri Thomas, Ziebuhr John, Thiel Volker, Siddell Stuart G, Davidson Andrew D, Snijder Eric J, Züst Roland, Putics Akos, Eriksson Klara K, Weber Friedemann
Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5
Züst R, Ludewig B, Siddell S, Diamond M, Barchet W, Baker S, Szretter K, Ziebuhr J, Neuman B, Maier R, Habjan M, Cervantes-Barragan L, Thiel V. Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5. Nat Immunol 2011; 12:137-43.
Jan 9, 2011Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5
Jan 9, 2011Nat Immunol 2011; 12:137-43
Züst Roland, Ludewig Burkhard, Siddell Stuart G, Diamond Michael S, Barchet Winfried, Baker Susan C, Szretter Kristy J, Ziebuhr John, Neuman Benjamin W, Maier Reinhard, Habjan Matthias, Cervantes-Barragan Luisa, Thiel Volker
2'-O methylation of the viral mRNA cap evades host restriction by IFIT family members
Daffis S, Shi P, Gale Jr M, Buller R, Pierson T, Klimstra W, Fensterl V, Sen G, Thiel V, Dong H, Züst R, Schneller S, Lin T, Errett J, Youn S, Li J, Schriewer J, Szretter K, Diamond M. 2'-O methylation of the viral mRNA cap evades host restriction by IFIT family members. Nature 2010; 468:452-456.
Nov 18, 20102'-O methylation of the viral mRNA cap evades host restriction by IFIT family members
Nov 18, 2010Nature 2010; 468:452-456
Daffis Stephane, Shi Pei-Yong, Gale Jr Michael, Buller R Mark, Pierson Theodore C, Klimstra William B, Fensterl Volker, Sen Ganes C, Thiel Volker, Dong Hongping, Züst Roland, Schneller Stewart, Lin Tsai-Yu, Errett John, Youn Soonjeon, Li Jianqing, Schriewer Jill, Szretter Kristy J, Diamond Michael S
Differentiation between human coronaviruses NL63 and 229E using a novel double-antibody sandwich enzyme-linked immunosorbent assay based on specific monoclonal antibodies
Sastre P, Dijkman R, Camuñas A, Ruiz T, Jebbink M, van der Hoek L, Vela C, Rueda P. Differentiation between human coronaviruses NL63 and 229E using a novel double-antibody sandwich enzyme-linked immunosorbent assay based on specific monoclonal antibodies. Clin Vaccine Immunol 2010; 18:113-8.
Nov 17, 2010Differentiation between human coronaviruses NL63 and 229E using a novel double-antibody sandwich enzyme-linked immunosorbent assay based on specific monoclonal antibodies
Nov 17, 2010Clin Vaccine Immunol 2010; 18:113-8
Sastre Patricia, Dijkman Ronald, Camuñas Ana, Ruiz Tamara, Jebbink Maarten F, van der Hoek Lia, Vela Carmen, Rueda Paloma
Virus-like particles expressing the nucleocapsid gene as an efficient vaccine against Rift Valley fever virus
Pichlmair A, Habjan M, Unger H, Weber F. Virus-like particles expressing the nucleocapsid gene as an efficient vaccine against Rift Valley fever virus. Vector Borne Zoonotic Dis 2010; 10:701-3.
Oct 1, 2010Virus-like particles expressing the nucleocapsid gene as an efficient vaccine against Rift Valley fever virus
Oct 1, 2010Vector Borne Zoonotic Dis 2010; 10:701-3
Pichlmair Andreas, Habjan Matthias, Unger Hermann, Weber Friedemann
Toscana virus induces interferon although its NSs protein reveals antagonistic activity
Gori Savellini G, Weber F, Terrosi C, Habjan M, Martorelli B, Cusi M. Toscana virus induces interferon although its NSs protein reveals antagonistic activity. J Gen Virol 2010; 92:71-9.
Sep 22, 2010Toscana virus induces interferon although its NSs protein reveals antagonistic activity
Sep 22, 2010J Gen Virol 2010; 92:71-9
Gori Savellini Gianni, Weber Friedemann, Terrosi Chiara, Habjan Matthias, Martorelli Barbara, Cusi Maria Grazia
Dendritic cell-specific antigen delivery by coronavirus vaccine vectors induces long-lasting protective antiviral and antitumor immunity
Cervantes-Barragan L, Ludewig B, Rohrlich P, Romero P, Speiser D, Levy F, Janda J, Sierro S, Maier R, Züst R, Thiel V. Dendritic cell-specific antigen delivery by coronavirus vaccine vectors induces long-lasting protective antiviral and antitumor immunity. MBio 2010; 1
Sep 14, 2010Dendritic cell-specific antigen delivery by coronavirus vaccine vectors induces long-lasting protective antiviral and antitumor immunity
Sep 14, 2010MBio 2010; 1
Cervantes-Barragan Luisa, Ludewig Burkhard, Rohrlich Pierre-Simon, Romero Pedro, Speiser Daniel, Levy Frederic, Janda Jozef, Sierro Sophie, Maier Reinhard, Züst Roland, Thiel Volker
Culturing the unculturable: human coronavirus HKU1 infects, replicates, and produces progeny virions in human ciliated airway epithelial cell cultures
Pyrc K, van der Hoek L, Baric R, Vabret A, Donaldson E, Deming D, Long C, Jebbink M, Dijkman R, Sims A, Pickles R. Culturing the unculturable: human coronavirus HKU1 infects, replicates, and produces progeny virions in human ciliated airway epithelial cell cultures. J Virol 2010; 84:11255-63.
Aug 18, 2010Culturing the unculturable: human coronavirus HKU1 infects, replicates, and produces progeny virions in human ciliated airway epithelial cell cultures
Aug 18, 2010J Virol 2010; 84:11255-63
Pyrc Krzysztof, van der Hoek Lia, Baric Ralph, Vabret Astrid, Donaldson Eric, Deming Damon, Long Casey, Jebbink Maarten, Dijkman Ronald, Sims Amy C, Pickles Raymond