Unit
Institute of Immunobiology
IMMBIO · Management
Preventing autoimmune myocarditis through cardiac myosin-specific tolerance
Jan 1, 2007The exact pathological basis of human myocarditis has not yet been sufficiently clarified and therefore, the appropriate treatment has remained a major clinical problem. Assuming that immunopathological damage contributes to the inflammatory nature o...
Fundamental Research - Jan 1, 2007 - Dec 31, 2009
Completed
Project leader: Ludewig Burkhard
Members: Nindl Veronika, Maier Reinhard
AIDS-CoVAC: Generation of a coronavirus-based multigene AIDS vaccine and evaluation in a preclinical SIV model
Dec 1, 2006Coronaviruses spread via mucosal surfaces and can infect dendritic cells. These features and their exceptional transcription strategy make them extremely promising candidate vaccine vectors to overcome known problems of current HIV vaccine approaches...
Fundamental Research - Dec 1, 2006 - May 31, 2009
Completed
Project leader: Ludewig Burkhard, Thiel Volker
Members: Eugster Karin, Cervantes-Barragan Luisa, Makia Divine
Coronavirus-based multigene HIV vaccine vectors
Jul 1, 2005The specific aim of this application is to provide the proof-of-principle that coronavirus vectors can indeed induce protective antiviral humoral and cellular immune responses in vivo. To this end, we will generate mouse hepatitis virus (MHV) vectors...
Fundamental Research - Jul 1, 2005 - Jun 30, 2007
Completed
Project leader: Thiel Volker
Members: Ludewig Burkhard
Complementary research action to support SARS-related diagnostic tests, therapeutic interventions and vaccine development – SARS-DTV
Oct 1, 2004The overall objective of the SARS-DTV network is to contribute to the development of candidate anti-SARS-CoV drugs, vaccines and diagnostic assays, by collaborative and complementary research divided into four Work packages. Molecular targets for ant...
Fundamental Research - Oct 1, 2004 - Sep 30, 2007
Completed
Project leader: Thiel Volker