Unit
Institute of Immunobiology
IMMBIO · Management
BP180-specific IgG is associated with skin adverse events, therapy response, and overall survival in non-small cell lung cancer patients treated with checkpoint inhibitors
Hasan Ali O, Sadik C, Zillikens D, Schmidt E, Jochum W, Mani B, Cozzio A, Braun A, Emtenani S, Hammers C, Abdou M, Diem S, Fässler M, Berner F, Ring S, Bomze D, Flatz L. BP180-specific IgG is associated with skin adverse events, therapy response, and overall survival in non-small cell lung cancer patients treated with checkpoint inhibitors. J Am Acad Dermatol 2019; 82:854-861.
Aug 23, 2019BP180-specific IgG is associated with skin adverse events, therapy response, and overall survival in non-small cell lung cancer patients treated with checkpoint inhibitors
Aug 23, 2019J Am Acad Dermatol 2019; 82:854-861
Hasan Ali Omar, Sadik Christian D, Zillikens Detlef, Schmidt Enno, Jochum Wolfram, Mani Bernhard, Cozzio Antonio, Braun Anne, Emtenani Shirin, Hammers Christoph, Abdou Marie-Therese, Diem Stefan, Fässler Mirjam, Berner Fiamma, Ring Sandra S, Bomze David, Flatz Lukas
Myocardial infarction triggers cardioprotective antigen-specific T helper cell responses
Rieckmann M, van der Laan A, Piek J, Koch C, Wester H, Lapa C, Bauer W, Ludewig B, Friedman N, Frantz S, Hofmann U, Krijnen P, Niessen H, Delgobo M, Gaal C, Büchner L, Steinau P, Reshef D, Gil Cruz C, Ter Horst E, Kircher M, Reiter T, Heinze K, Ramos G. Myocardial infarction triggers cardioprotective antigen-specific T helper cell responses. J Clin Invest 2019; 130
Aug 13, 2019Myocardial infarction triggers cardioprotective antigen-specific T helper cell responses
Aug 13, 2019J Clin Invest 2019; 130
Rieckmann Max, van der Laan Anja M, Piek Jan J, Koch Charlotte, Wester Hans-Jürgen, Lapa Constantin, Bauer Wolfgang R, Ludewig Burkhard, Friedman Nir, Frantz Stefan, Hofmann Ulrich, Krijnen Paul Aj, Niessen Hans Wm, Delgobo Murilo, Gaal Chiara, Büchner Lotte, Steinau Philipp, Reshef Dan, Gil Cruz Cristina, Ter Horst Ellis N, Kircher Malte, Reiter Theresa, Heinze Katrin G, Ramos Gustavo Campos
Association of Checkpoint Inhibitor-Induced Toxic Effects With Shared Cancer and Tissue Antigens in Non-Small Cell Lung Cancer
Berner F, Hartmann F, Cheng H, Hönger G, Recher M, Goldman J, Cozzio A, Früh M, Neefjes J, Driessen C, Ludewig B, Hegazy A, Jochum W, Speiser D, Zippelius A, Läubli H, Bomze D, Diem S, Ali O, Fässler M, Ring S, Niederer R, Ackermann C, Baumgaertner P, Pikor N, Cruz C, van de Veen W, Akdis M, Nikolaev S, Flatz L. Association of Checkpoint Inhibitor-Induced Toxic Effects With Shared Cancer and Tissue Antigens in Non-Small Cell Lung Cancer. JAMA Oncol 2019; 5:1043-1047.
Jul 1, 2019Association of Checkpoint Inhibitor-Induced Toxic Effects With Shared Cancer and Tissue Antigens in Non-Small Cell Lung Cancer
Jul 1, 2019JAMA Oncol 2019; 5:1043-1047
Berner Fiamma, Hartmann Fabienne, Cheng Hung-Wei, Hönger Gideon, Recher Mike, Goldman Jonathan, Cozzio Antonio, Früh Martin, Neefjes Jacques, Driessen Christoph, Ludewig Burkhard, Hegazy Ahmed N, Jochum Wolfram, Speiser Daniel E, Zippelius Alfred, Läubli Heinz, Bomze David, Diem Stefan, Ali Omar Hasan, Fässler Mirjam, Ring Sandra, Niederer Rebekka, Ackermann Christoph J, Baumgaertner Petra, Pikor Natalia, Cruz Cristina Gil, van de Veen Willem, Akdis Mübeccel, Nikolaev Sergey, Flatz Lukas
Lymph Node Mesenchymal and Endothelial Stromal Cells Cooperate via the RANK-RANKL Cytokine Axis to Shape the Sinusoidal Macrophage Niche
Camara A, Flacher V, Ludewig B, Yagita H, Tanaka M, Asano K, Onder L, Chypre M, Sponsel J, Alloush F, Cordeiro O, Mueller C. Lymph Node Mesenchymal and Endothelial Stromal Cells Cooperate via the RANK-RANKL Cytokine Axis to Shape the Sinusoidal Macrophage Niche. Immunity 2019; 50:1467-1481.e6.
Jun 11, 2019Lymph Node Mesenchymal and Endothelial Stromal Cells Cooperate via the RANK-RANKL Cytokine Axis to Shape the Sinusoidal Macrophage Niche
Jun 11, 2019Immunity 2019; 50:1467-1481.e6
Camara Abdouramane, Flacher Vincent, Ludewig Burkhard, Yagita Hideo, Tanaka Masato, Asano Kenichi, Onder Lucas, Chypre Mélanie, Sponsel Janina, Alloush Farouk, Cordeiro Olga G, Mueller Christopher G
Systems analysis reveals complex biological processes during virus infection fate decisions
Argilaguet J, Heath S, Ludewig B, Bocharov G, Kaisho T, Andreu D, Casella V, Gil Cruz C, Vidal E, Riera G, Esteve-Codina A, Pedragosa M, Meyerhans A. Systems analysis reveals complex biological processes during virus infection fate decisions. Genome Res 2019; 29:907-919.
May 28, 2019Systems analysis reveals complex biological processes during virus infection fate decisions
May 28, 2019Genome Res 2019; 29:907-919
Argilaguet Jordi, Heath Simon, Ludewig Burkhard, Bocharov Gennady, Kaisho Tsuneyasu, Andreu David, Casella Valentina, Gil Cruz Cristina, Vidal Enric, Riera Graciela, Esteve-Codina Anna, Pedragosa Mireia, Meyerhans Andreas
IL-4Rα-Expressing B Cells Are Required for CXCL13 Production by Fibroblastic Reticular Cells
Dubey L, Ludewig B, Luther S, Harris N. IL-4Rα-Expressing B Cells Are Required for CXCL13 Production by Fibroblastic Reticular Cells. Cell Rep 2019; 27:2442-2458.e5.
May 21, 2019IL-4Rα-Expressing B Cells Are Required for CXCL13 Production by Fibroblastic Reticular Cells
May 21, 2019Cell Rep 2019; 27:2442-2458.e5
Dubey Lalit Kumar, Ludewig Burkhard, Luther Sanjiv A, Harris Nicola L
Divergent memory responses driven by adenoviral vectors are impacted by epitope competition
Colston J, Hutchings C, Chinnakannan S, Highton A, Pérez Shibayama C, Ludewig B, Klenerman P. Divergent memory responses driven by adenoviral vectors are impacted by epitope competition. Eur J Immunol 2019
May 20, 2019Divergent memory responses driven by adenoviral vectors are impacted by epitope competition
May 20, 2019Eur J Immunol 2019
Colston Julia M, Hutchings Claire, Chinnakannan Senthil, Highton Andrew, Pérez Shibayama Christian Ivan, Ludewig Burkhard, Klenerman Paul
Fibroblastic reticular cells at the nexus of innate and adaptive immune responses
Pérez Shibayama C, Gil Cruz C, Ludewig B. Fibroblastic reticular cells at the nexus of innate and adaptive immune responses. Immunol Rev 2019; 289:31-41.
May 1, 2019Fibroblastic reticular cells at the nexus of innate and adaptive immune responses
May 1, 2019Immunol Rev 2019; 289:31-41
Pérez Shibayama Christian Ivan, Gil Cruz Cristina, Ludewig Burkhard
Origin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp
Cheng H, Hehlgans T, Rülicke T, Pfeffer K, Sorg U, Tersteegen A, Miyazaki J, Robinson M, Scandella E, Pikor N, Lütge M, Soneson C, Novkovic M, Onder L, Ludewig B. Origin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp. Nat Commun 2019; 10:1739.
Apr 15, 2019Origin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp
Apr 15, 2019Nat Commun 2019; 10:1739
Cheng Hung-Wei, Hehlgans Thomas, Rülicke Thomas, Pfeffer Klaus, Sorg Ursula, Tersteegen Anne, Miyazaki Jun-Ichi, Robinson Mark D, Scandella Elke, Pikor Natalia, Lütge Mechthild, Soneson Charlotte, Novkovic Mario, Onder Lucas, Ludewig Burkhard
Immunoglobulin G and Subclasses as Potential Biomarkers in Metastatic Melanoma Patients Starting Checkpoint Inhibitor Treatment
Diem S, Risch M, Recher M, Risch L, Dummer R, Levesque M, Mangana J, Hillmann D, Niederer R, Berner F, Ali O, Bomze D, Fässler M, Flatz L. Immunoglobulin G and Subclasses as Potential Biomarkers in Metastatic Melanoma Patients Starting Checkpoint Inhibitor Treatment. J Immunother 2019; 42:89-93.
Apr 1, 2019Immunoglobulin G and Subclasses as Potential Biomarkers in Metastatic Melanoma Patients Starting Checkpoint Inhibitor Treatment
Apr 1, 2019J Immunother 2019; 42:89-93
Diem Stefan, Risch Martin, Recher Mike, Risch Lorenz, Dummer Reinhard, Levesque Mitchell P, Mangana Joanna, Hillmann Dorothea, Niederer Rebekka, Berner Fiamma, Ali Omar Hasan, Bomze David, Fässler Mirjam, Flatz Lukas
Rolf Zinkernagel and the co-discovery of MHC restriction together with Peter Doherty
Ludewig B. Rolf Zinkernagel and the co-discovery of MHC restriction together with Peter Doherty. Allergy 2019
Mar 27, 2019Rolf Zinkernagel and the co-discovery of MHC restriction together with Peter Doherty
Mar 27, 2019Allergy 2019
Ludewig Burkhard
TLR7 Controls VSV Replication in CD169 SCS Macrophages and Associated Viral Neuroinvasion
Solmaz G, Lang K, Wagner H, Clausen B, Ludewig B, Kalinke U, Khairnar V, Duhan V, Swallow M, Guderian M, Lindenberg M, Francozo M, Puttur F, Sparwasser T. TLR7 Controls VSV Replication in CD169 SCS Macrophages and Associated Viral Neuroinvasion. Front Immunol 2019; 10:466.
Mar 15, 2019TLR7 Controls VSV Replication in CD169 SCS Macrophages and Associated Viral Neuroinvasion
Mar 15, 2019Front Immunol 2019; 10:466
Solmaz Gülhas, Lang Karl S, Wagner Hermann, Clausen Björn E, Ludewig Burkhard, Kalinke Ulrich, Khairnar Vishal, Duhan Vikas, Swallow Maxine, Guderian Melanie, Lindenberg Marc, Francozo Marcela, Puttur Franz, Sparwasser Tim D
Antibodies as biomarker candidates for response and survival to checkpoint inhibitors in melanoma patients
Fässler M, Jörger M, Recher M, Risch L, Güsewell S, Risch M, Speiser D, Ludewig B, Levesque M, Dummer R, Siano M, Krolik M, Diem S, Mangana J, Hasan Ali O, Berner F, Bomze D, Ring S, Niederer R, Gil Cruz C, Pérez Shibayama C, Flatz L. Antibodies as biomarker candidates for response and survival to checkpoint inhibitors in melanoma patients. J Immunother Cancer 2019; 7:50.
Feb 20, 2019Antibodies as biomarker candidates for response and survival to checkpoint inhibitors in melanoma patients
Feb 20, 2019J Immunother Cancer 2019; 7:50
Fässler Mirjam, Jörger Markus, Recher Mike, Risch Lorenz, Güsewell Sabine, Risch Martin, Speiser Daniel E, Ludewig Burkhard, Levesque Mitchell P, Dummer Reinhard, Siano Marco, Krolik Michal, Diem Stefan, Mangana Joanna, Hasan Ali Omar, Berner Fiamma, Bomze David, Ring Sandra, Niederer Rebekka, Gil Cruz Cristina, Pérez Shibayama Christian Ivan, Flatz Lukas
A Variant of a Killer Cell Immunoglobulin-like Receptor Is Associated with Resistance to PD-1 Blockade in Lung Cancer
Trefny M, Savic S, Jermann P, Alborelli I, Schaub S, Stenner F, Früh M, Trajanoski Z, Flatz L, Mertz K, Zippelius A, Geier F, Thommen D, Rothschild S, Uhlenbrock F, Rieder D, Kasenda B, Stanczak M, Berner F, Kashyap A, Kaiser M, Herzig P, Poechtrager S, Läubli H. A Variant of a Killer Cell Immunoglobulin-like Receptor Is Associated with Resistance to PD-1 Blockade in Lung Cancer. Clin Cancer Res 2019; 25:3026-3034.
Feb 14, 2019A Variant of a Killer Cell Immunoglobulin-like Receptor Is Associated with Resistance to PD-1 Blockade in Lung Cancer
Feb 14, 2019Clin Cancer Res 2019; 25:3026-3034
Trefny Marcel P, Savic Spasenija, Jermann Philip, Alborelli Ilaria, Schaub Stefan, Stenner Frank, Früh Martin, Trajanoski Zlatko, Flatz Lukas, Mertz Kirsten D, Zippelius Alfred, Geier Florian, Thommen Daniela S, Rothschild Sacha I, Uhlenbrock Franziska, Rieder Dietmar, Kasenda Benjamin, Stanczak Michal A, Berner Fiamma, Kashyap Abhishek S, Kaiser Monika, Herzig Petra, Poechtrager Severin, Läubli Heinz
Type I interferon induces CXCL13 to support ectopic germinal center formation
Denton A, Good-Jacobson K, Groom J, Ludewig B, Mörbe U, Mabbott N, Lafouresse F, Bradford B, Carr E, Innocentin S, Linterman M. Type I interferon induces CXCL13 to support ectopic germinal center formation. J Exp Med 2019
Feb 5, 2019Type I interferon induces CXCL13 to support ectopic germinal center formation
Feb 5, 2019J Exp Med 2019
Denton Alice E, Good-Jacobson Kim L, Groom Joanna R, Ludewig Burkhard, Mörbe Urs, Mabbott Neil A, Lafouresse Fanny, Bradford Barry M, Carr Edward J, Innocentin Silvia, Linterman Michelle A
Human leukocyte antigen variation is associated with adverse events of checkpoint inhibitors
Hasan Ali O, Lenz T, Driessen C, Früh M, Jörger M, Cozzio A, Diem S, Fässler M, Bomze D, Berner F, Flatz L. Human leukocyte antigen variation is associated with adverse events of checkpoint inhibitors. Eur J Cancer 2018; 107:8-14.
Dec 7, 2018Human leukocyte antigen variation is associated with adverse events of checkpoint inhibitors
Dec 7, 2018Eur J Cancer 2018; 107:8-14
Hasan Ali Omar, Lenz Tobias L, Driessen Christoph, Früh Martin, Jörger Markus, Cozzio Antonio, Diem Stefan, Fässler Mirjam, Bomze David, Berner Fiamma, Flatz Lukas
Myocarditis Elicits Dendritic Cell and Monocyte Infiltration in the Heart and Self-Antigen Presentation by Conventional Type 2 Dendritic Cells
Van der Borght K, Gillebert T, Ludewig B, Boon L, Saeys Y, Nindl V, Van Isterdael G, Sichien D, Martens L, Scott C, Lambrecht B. Myocarditis Elicits Dendritic Cell and Monocyte Infiltration in the Heart and Self-Antigen Presentation by Conventional Type 2 Dendritic Cells. Front Immunol 2018; 9:2714.
Nov 21, 2018Myocarditis Elicits Dendritic Cell and Monocyte Infiltration in the Heart and Self-Antigen Presentation by Conventional Type 2 Dendritic Cells
Nov 21, 2018Front Immunol 2018; 9:2714
Van der Borght Katrien, Gillebert Thierry C, Ludewig Burkhard, Boon Louis, Saeys Yvan, Nindl Veronika, Van Isterdael Gert, Sichien Dorine, Martens Liesbet, Scott Charlotte L, Lambrecht Bart N
Risk score for non-small cell lung cancer patients starting checkpoint inhibitor treatment
Diem S, Früh M, Güsewell S, Schmid S, Ackermann C, Roux G, Berner F, Niederer R, Siano M, Ali O, Fässler M, Flatz L. Risk score for non-small cell lung cancer patients starting checkpoint inhibitor treatment. Cancer Manag Res 2018; 10:5537-5544.
Nov 8, 2018Risk score for non-small cell lung cancer patients starting checkpoint inhibitor treatment
Nov 8, 2018Cancer Manag Res 2018; 10:5537-5544
Diem Stefan, Früh Martin, Güsewell Sabine, Schmid Sabine, Ackermann Christoph Jakob, Roux Guillaume-Alexandre, Berner Fiamma, Niederer Rebekka, Siano Marco, Ali Omar Hasan, Fässler Mirjam, Flatz Lukas
Essential Role of Canonical NF-κB Activity in the Development of Stromal Cell Subsets in Secondary Lymphoid Organs
Bogdanova D, Takeuchi A, Ozawa M, Kanda Y, Rahman M, Ludewig B, Kinashi T, Katakai T. Essential Role of Canonical NF-κB Activity in the Development of Stromal Cell Subsets in Secondary Lymphoid Organs. J Immunol 2018; 201:3580-3586.
Nov 5, 2018Essential Role of Canonical NF-κB Activity in the Development of Stromal Cell Subsets in Secondary Lymphoid Organs
Nov 5, 2018J Immunol 2018; 201:3580-3586
Bogdanova Dana, Takeuchi Arata, Ozawa Madoka, Kanda Yasuhiro, Rahman M Azizur, Ludewig Burkhard, Kinashi Tatsuo, Katakai Tomoya
Redefining the Nature of Lymphoid Tissue Organizer Cells: Response to 'Complexity of Lymphoid Tissue Organizers' by Koning and Mebius
Onder L, Ludewig B. Redefining the Nature of Lymphoid Tissue Organizer Cells: Response to 'Complexity of Lymphoid Tissue Organizers' by Koning and Mebius. Trends Immunol 2018; 39:952-953.
Nov 2, 2018Redefining the Nature of Lymphoid Tissue Organizer Cells: Response to 'Complexity of Lymphoid Tissue Organizers' by Koning and Mebius
Nov 2, 2018Trends Immunol 2018; 39:952-953
Onder Lucas, Ludewig Burkhard