Publication

Critical appraisal of meta-analyses: an introductory guide for the practicing surgeon

Journal Paper/Review - Jul 22, 2009

Units
PubMed
Doi

Citation
Lawrentschuk N, McCall J, Gueller U. Critical appraisal of meta-analyses: an introductory guide for the practicing surgeon. Patient Saf Surg 2009; 3:16.
Type
Journal Paper/Review (English)
Journal
Patient Saf Surg 2009; 3
Publication Date
Jul 22, 2009
Issn Electronic
1754-9493
Pages
16
Brief description/objective

Meta-analyses are an essential tool of clinical research. Meta-analyses of individual randomized controlled trials frequently constitute the highest possible level of scientific evidence for a given research question and allow surgeons to rapidly gain a comprehensive understanding of an important clinical issue. Moreover, meta-analyses often serve as cornerstones for evidence-based surgery, treatment guidelines, and knowledge transfer. Given the importance of meta-analyses to the medical (and surgical) knowledge base, it is of cardinal importance that surgeons have a basic grasp of the principles that guide a high-quality meta-analysis, and be able to weigh objectively the advantages and potential pitfalls of this clinical research tool. Unfortunately, surgeons are often ill-prepared to successfully conduct, critically appraise, and correctly interpret meta-analyses. The objective of this educational review is to provide surgeons with a brief introductory overview of the knowledge and skills required for understanding and critically appraising surgical meta-analyses as well as assessing their implications for their own surgical practice.