Inter-observer agreement for spectral- and time-domain optical coherence tomography image grading: a prospective study

Publication

Inter-observer agreement for spectral- and time-domain optical coherence tomography image grading: a prospective study

Journal Paper/Review - Sep 22, 2012

Knecht Pascal B, Kordic Helena, Kurz-Levin Malaika, Sturm Veit, Menke Marcel N

Citation

Knecht P, Kordic H, Kurz-Levin M, Sturm V, Menke M. Inter-observer agreement for spectral- and time-domain optical coherence tomography image grading: a prospective study. Int Ophthalmol 2012; 33:47-52.

Type

Journal Paper/Review (English)

Journal

Int Ophthalmol 2012; 33

Publication Date

Sep 22, 2012

Issn Electronic

1573-2630

Pages

47-52

Brief description/objective

The purpose of this study was to compare inter-observer agreement of Stratus™ OCT versus Spectralis™ OCT image grading in patients with neovascular age-related macular degeneration (AMD). Thirty eyes with neovascular AMD were examined with Stratus™ OCT and Spectralis™ OCT. Four different scan protocols were used for imaging. Three observers graded the images for the presence of various pathologies. Inter-observer agreement between OCT models was assessed by calculating intra-class correlation coefficients (ICC). In Stratus™ OCT highest interobserver agreement was found for subretinal fluid (ICC: 0.79), and in Spectralis™ OCT for intraretinal cysts (IRC) (ICC: 0.93). Spectralis™ OCT showed superior interobserver agreement for IRC and epiretinal membranes (ERM) (ICC(Stratus™): for IRC 0.61; for ERM 0.56; ICC(Spectralis™): for IRC 0.93; for ERM 0.84). Increased image resolution of Spectralis™ OCT did improve the inter-observer agreement for grading intraretinal cysts and epiretinal membranes but not for other retinal changes.