Major tumor regression after paclitaxel and carboplatin polychemotherapy in a patient with advanced penile cancer

Publication

Major tumor regression after paclitaxel and carboplatin polychemotherapy in a patient with advanced penile cancer

Journal Paper/Review - Apr 1, 2004

Jörger Markus, Warzinek T, Klaeser B, Kluckert J T, Schmid H-P, Gillessen Sommer Silke

Citation

Jörger M, Warzinek T, Klaeser B, Kluckert J, Schmid H, Gillessen Sommer S. Major tumor regression after paclitaxel and carboplatin polychemotherapy in a patient with advanced penile cancer. Urology 2004; 63:778-80.

Type

Journal Paper/Review (English)

Journal

Urology 2004; 63

Publication Date

Apr 1, 2004

Issn Electronic

1527-9995

Pages

778-80

Brief description/objective

Penile cancer is rare in Western countries. High-risk patients are considered for prophylactic inguinal lymphadenectomy. For advanced disease, a triplet drug regimen consisting of bleomycin, methotrexate, and cisplatin is the most active combination tested so far. A 62-year-old man with penile cancer underwent partial penile amputation but presented 10 months later with inguinal nodal metastasis. He received three cycles of paclitaxel/carboplatin with marked clinical and radiologic (computed tomography and positron emission tomography) tumor regression. Later, complete resection of the inguinal nodal metastasis was performed. The paclitaxel/carboplatin combination has potential activity in penile cancer. Positron emission tomography may be used for screening of nodal metastases.