European consensus conference on diagnosis and treatment of germ cell cancer: a report of the second meeting of the European Germ Cell Cancer Consensus group (EGCCCG): part I

Publication

European consensus conference on diagnosis and treatment of germ cell cancer: a report of the second meeting of the European Germ Cell Cancer Consensus group (EGCCCG): part I

Journal Paper/Review - Mar 1, 2008

Kisbenedek László, Mueller Rolf, Nichols Craig, Nicolai Nicola, Oliver Tim, Ondrus Dalibor, Oosterhof Gosse O N, Ares Luis Paz, Pizzocaro Giorgio, Mead Graham M, Mason Malcolm D, Klepp Olbjørn, Kliesch Sabine, Koehrmann Kai Uwe, Kollmannsberger Christian, Kuczyk Markus, Laguna Pilar, Galvis Oscar Leiva, Loy Volker, Pont Jörg, Pottek Tobias, Powles Tom, Sohaib Aslam, Tjulandin Sergei, Warde Padraig, Weinknecht Stefan, Weissbach Lothar, Wittekind Christian, Winter Eva, Wood Lori, Skakkebaek Niels E, Sedlmayer Felix, Rick Oliver, Rosti Giovanni, Salvioni Roberto, Scheiderbauer Jutta, Schmelz Hans-Ulrich, Schmidberger Heinz, Schmoll Hans-Joachim, Schrader Mark, von der Maase Hans, Jones William G, Krege Susanne, Clemm Christoph, Cohn-Cedermark Gabriella, Culine Stéphane, Daugaard Gedske, De Mulder Pieter H M, De Santis Maria, de Wit Maike, de Wit Ronald, Classen Johannes, Cavallin-Ståhl Eva, Beyer Jörg, Souchon Rainer, Albers Peter, Albrecht Walter, Algaba Ferran, Bamberg Michael, Bodrogi István, Bokemeyer Carsten, Derigs Hans Günter, Dieckmann Klaus-Peter, Dieing Annette, Gillessen Sommer Silke, Hartmann Jörg T, Hartmann Michael, Heidenreich Axel, Hoeltl Wolfgang, Horwich Alan, Huddart Robert, Jewett Michael, Germa-Lluch Jose Ramon, Gerl Arthur, Droz Jean-Pierre, Fenner Martin, Fizazi Karim, Flechon Aude, Fosså Sophie D, del Muro Xavier Garcia, Gauler Thomas, Geczi Lajos, Joffe Johnathan

Units

Medizinische Onkologie und Hämatologie

Keywords

Prostatakrebs

PubMed

18191324

Doi

10.1016/j.eururo.2007.12.024

Citation

Kisbenedek L, Mueller R, Nichols C, Nicolai N, Oliver T, Ondrus D, Oosterhof G, Ares L, Pizzocaro G, Mead G, Mason M, Klepp O, Kliesch S, Koehrmann K, Kollmannsberger C, Kuczyk M, Laguna P, Galvis O, Loy V, Pont J, Pottek T, Powles T, Sohaib A, Tjulandin S, Warde P, Weinknecht S, Weissbach L, Wittekind C, Winter E, Wood L, Skakkebaek N, Sedlmayer F, Rick O, Rosti G, Salvioni R, Scheiderbauer J, Schmelz H, Schmidberger H, Schmoll H, Schrader M, von der Maase H, Jones W, Krege S, Clemm C, Cohn-Cedermark G, Culine S, Daugaard G, De Mulder P, De Santis M, de Wit M, de Wit R, Classen J, Cavallin-Ståhl E, Beyer J, Souchon R, Albers P, Albrecht W, Algaba F, Bamberg M, Bodrogi I, Bokemeyer C, Derigs H, Dieckmann K, Dieing A, Gillessen Sommer S, Hartmann J, Hartmann M, Heidenreich A, Hoeltl W, Horwich A, Huddart R, Jewett M, Germa-Lluch J, Gerl A, Droz J, Fenner M, Fizazi K, Flechon A, Fosså S, del Muro X, Gauler T, Geczi L, Joffe J. European consensus conference on diagnosis and treatment of germ cell cancer: a report of the second meeting of the European Germ Cell Cancer Consensus group (EGCCCG): part I. European urology 2008; 53:478-96.

Type

Journal Paper/Review (English)

Journal

European urology 2008; 53

Publication Date

Mar 1, 2008

Issn Print

0302-2838

Pages

478-96

Brief description/objective

OBJECTIVES: The first consensus report presented by the European Germ Cell Cancer Consensus Group (EGCCCG) in the year 2004 has found widespread approval by many colleagues throughout the world. In November 2006, the group met a second time under the auspices of the Department of Urology of the Amsterdam Medical Center, Amsterdam, The Netherlands. METHODS: Medical oncologists, urological surgeons, radiation oncologists as well as pathologists from several European countries reviewed and discussed the data that had emerged since the 2002 conference, and incorporated the new data into updated and revised guidelines. As for the first meeting, the methodology of evidence-based medicine (EBM) was applied. The results of the discussion were compiled by the writing committee. All participants have agreed to this final update. RESULTS: The first part of the consensus paper describes the clinical presentation of the primary tumor, its treatment, the importance and treatment of testicular intraepithelial neoplasia (TIN), histological classification, staging and prognostic factors, and treatment of stage I seminoma and non-seminoma. CONCLUSIONS: Whereas the vast majority of the recommendations made in 2004 remain valid 3 yr later, refinements in the treatment of early- and advanced-stage testicular cancer have emerged from clinical trials. Despite technical improvements, expert clinical skills will continue to be one of the major determinants for the prognosis of patients with germ cell cancer. In addition, the particular needs of testicular cancer survivors have been acknowledged.