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Early severe nonimmune hydrops fetalis: Do not give up, it is not always fatal!
Journal Paper/Review - Nov 1, 2010
Putora Katharina, Malzacher Andreas, Drack Gero
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Hydrops fetalis (HF) is defined as the presence of excessive fluid accumulation in at least two fetal body cavities(1). It occurs in 1/1'500-4'000 pregnandes (2,3) Two major groups can be diffentiated immune /HF) an nonimmune hydrops fetalis(NIHF). IHF is almost always due to erythroblastosis caused by Rh alloimmunization. In the past, IHF was much more common than NHF (incidence ratio of 9:1)(4). Nowadays in the era of routine immunization of Rh negative mothers, abaut 80 percent of cases are NHF (3)
Although diagnosis an mangement has improved in recent years, NHF is still associated with a high fetal mortalityrate, which varies despending on the etiology between 50 to 90 percent (3,6). To the best of our knowledge, thus far no case of spontaneous regression of idopathik. NHF has been published. Therefore, we report on a patient with sponteneous regression of early severe an prolonged NHF.