Can antiretroviral therapy be used to prevent sexual transmission of human immunodeficiency virus type 1?

Publication

Can antiretroviral therapy be used to prevent sexual transmission of human immunodeficiency virus type 1?

Journal Paper/Review - May 15, 2002

Hosseinipour Mina, Cohen Myron S, Vernazza Pietro, Kashuba Angela D M

Citation

Hosseinipour M, Cohen M, Vernazza P, Kashuba A. Can antiretroviral therapy be used to prevent sexual transmission of human immunodeficiency virus type 1?. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2002; 34:1391-5.

Type

Journal Paper/Review (English)

Journal

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2002; 34

Publication Date

May 15, 2002

Issn Electronic

1537-6591

Pages

1391-5

Brief description/objective

Approximately 5 million people annually are newly infected with human immunodeficiency virus (HIV). Although education, behavior modification, and promotion of condom use are effective transmission-prevention measures, the severity of the pandemic demands that all possible prevention strategies be explored. Antiretroviral therapy has the potential to decrease sexual transmission of HIV type 1 by reducing levels of HIV RNA and thus decreasing the risk that infected persons will transmit the disease or by its use as preexposure or postexposure prophylaxis. In this article, we explore the rationale for using antiretroviral therapy to prevent sexual transmission of HIV, as well as the limitations of this approach.