Angiogenesis and lymphangiogenesis are downregulated in primary breast cancer

Publication

Angiogenesis and lymphangiogenesis are downregulated in primary breast cancer

Journal Paper/Review - Aug 18, 2009

Boneberg E-M, Senn H-J, Otto F, Dupont-Lampert V, Beer G M, Füzesi L, Steininger H, Öhlschlegel Christian, Hoefer M M, Legler D F, Fürstenberger G

Citation

Boneberg E, Senn H, Otto F, Dupont-Lampert V, Beer G, Füzesi L, Steininger H, Öhlschlegel C, Hoefer M, Legler D, Fürstenberger G. Angiogenesis and lymphangiogenesis are downregulated in primary breast cancer. Br J Cancer 2009; 101:605-14.

Type

Journal Paper/Review (English)

Journal

Br J Cancer 2009; 101

Publication Date

Aug 18, 2009

Issn Electronic

1532-1827

Pages

605-14

Brief description/objective

Angiogenesis and lymphangiogenesis are considered to play key roles in tumour growth, progression and metastasis. However, targeting tumour angiogenesis in clinical trials showed only modest efficacy. We therefore scrutinised the concept of tumour angiogenesis and lymphangiogenesis by analysing the expression of crucial markers involved in these processes in primary breast cancer.