Early sevoflurane sedation in severe COVID-19-related lung injury patients. A pilot randomized controlled trial.

Publication

Early sevoflurane sedation in severe COVID-19-related lung injury patients. A pilot randomized controlled trial.

Journal Paper/Review - Mar 27, 2024

Beck-Schimmer Beatrice, Schadde Erik, Pietsch Urs, Filipovic Miodrag, Dübendorfer-Dalbert Seraina, Fodor Patricia, Hübner Tobias, Schuepbach Reto Andreas, Steiger Peter, David Sascha, Krüger Bernard D, Neff Thomas A, Schläpfer Martin

Citation

Beck-Schimmer B, Schadde E, Pietsch U, Filipovic M, Dübendorfer-Dalbert S, Fodor P, Hübner T, Schuepbach R, Steiger P, David S, Krüger B, Neff T, Schläpfer M. Early sevoflurane sedation in severe COVID-19-related lung injury patients. A pilot randomized controlled trial. Ann Intensive Care 2024; 14:41.

Type

Journal Paper/Review (English)

Journal

Ann Intensive Care 2024; 14

Publication Date

Mar 27, 2024

Issn Print

2110-5820

Brief description/objective

This study aimed to assess a potential organ protective effect of volatile sedation in a scenario of severe inflammation with an early cytokine storm (in particular IL-6 elevation) in patients suffering from COVID-19-related lung injury with invasive mechanical ventilation and sedation.