Thrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke: an open-label, blinded-outcome, randomised non-inferiority trial.

Publication

Thrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke: an open-label, blinded-outcome, randomised non-inferiority trial.

Journal Paper/Review - Jul 9, 2022

Fischer Urs, Kaesmacher Johannes, Strbian Daniel, Eker Omer Faruk, Cognard Christophe, Plattner Patricia S, Buetikofer Lukas, Mordasini Pasquale, Deppeler Sandro, Mendes Pereira Vitor, Albucher Jean François, Darcourt Jean, Bourcier Romain, Guillon Benoit, Papagiannaki Chrysanthi, Ozkul-Wermester Ozlem, Sibolt Gerli, Tiainen Marjaana, Gory Benjamin, Richard Sébastien, Liman Jan, Ernst Marielle Sophie, Boulanger Marion, Barbier Charlotte, Mechtouff Laura, Zhang Liqun, Marnat Gaultier, Sibon Igor, Nikoubashman Omid, Reich Arno, Consoli Arturo, Lapergue Bertrand, Ribó Marc, Tomasello Alejandro, Saleme Suzana, Macian Francisco, Moulin Solène, Pagano Paolo, Saliou Guillaume, Carrera Emmanuel, Janot Kevin, Hernández-Pérez María, Pop Raoul, Della Schiava Lucie, Luft Andreas R, Piotin Michel, Gentric Jean-Christophe, Pikula Aleksandra, Pfeilschifter Waltraud, Arnold Marcel, Siddiqui Adnan, Froehler Michael T, Furlan Anthony J, Chapot René, Wiesmann Martin, Machi Paolo, Diener Hans-Christoph, Kulcsar Zsolt, Bonati Leo H, Bassetti Claudio L, Mazighi Mikaël, Liebeskind David S, Saver Jeffrey L, Gralla Jan, SWIFT DIRECT Collaborators

Citation

Fischer U, Kaesmacher J, Strbian D, Eker O, Cognard C, Plattner P, Buetikofer L, Mordasini P, Deppeler S, Mendes Pereira V, Albucher J, Darcourt J, Bourcier R, Guillon B, Papagiannaki C, Ozkul-Wermester O, Sibolt G, Tiainen M, Gory B, Richard S, Liman J, Ernst M, Boulanger M, Barbier C, Mechtouff L, Zhang L, Marnat G, Sibon I, Nikoubashman O, Reich A, Consoli A, Lapergue B, Ribó M, Tomasello A, Saleme S, Macian F, Moulin S, Pagano P, Saliou G, Carrera E, Janot K, Hernández-Pérez M, Pop R, Della Schiava L, Luft A, Piotin M, Gentric J, Pikula A, Pfeilschifter W, Arnold M, Siddiqui A, Froehler M, Furlan A, Chapot R, Wiesmann M, Machi P, Diener H, Kulcsar Z, Bonati L, Bassetti C, Mazighi M, Liebeskind D, Saver J, Gralla J, SWIFT DIRECT Collaborators. Thrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke: an open-label, blinded-outcome, randomised non-inferiority trial. Lancet 2022; 400:104-115.

Type

Journal Paper/Review (English)

Journal

Lancet 2022; 400

Publication Date

Jul 9, 2022

Issn Electronic

1474-547X

Pages

104-115

Brief description/objective

Whether thrombectomy alone is equally as effective as intravenous alteplase plus thrombectomy remains controversial. We aimed to determine whether thrombectomy alone would be non-inferior to intravenous alteplase plus thrombectomy in patients presenting with acute ischaemic stroke.