Immune monitoring-guided vs fixed duration of antiviral prophylaxis against cytomegalovirus in solid-organ transplant recipients. A Multicenter, Randomized Clinical Trial.

Publication

Immune monitoring-guided vs fixed duration of antiviral prophylaxis against cytomegalovirus in solid-organ transplant recipients. A Multicenter, Randomized Clinical Trial.

Journal Paper/Review - Sep 22, 2023

Manuel Oriol, Laager Mirjam, Hirzel Cédric, Neofytos Dionysios, Walti Laura N, Hönger Gideon, Binet Françoise-Isabelle, Schnyder Aurelia, Stampf Susanne, Koller Michael, Mombelli Matteo, Kim Min Jeong, Hoffmann Matthias, Koenig Katrin, Hess Christoph, Burgener Anne-Valérie, Cippà Pietro E, Hübel Kerstin, Müller Thomas F, Sidler Daniel, Dahdal Suzan, Suter-Riniker Franziska, Villard Jean, Zbinden Andrea, Pantaleo Giuseppe, Semmo Nasser, Hadaya Karine, Enriquez Natalia, Meylan Pascal R, Froissart Marc, Golshayan Délaviz, Fehr Thomas, Huynh-Do Uyen, Pascual Manuel, Van Delden Christian, Hirsch Hans H., Jüni Peter, Müller Nicolas J., Swiss Transplant Cohort Study (STCS)

Citation

Manuel O, Laager M, Hirzel C, Neofytos D, Walti L, Hönger G, Binet F, Schnyder A, Stampf S, Koller M, Mombelli M, Kim M, Hoffmann M, Koenig K, Hess C, Burgener A, Cippà P, Hübel K, Müller T, Sidler D, Dahdal S, Suter-Riniker F, Villard J, Zbinden A, Pantaleo G, Semmo N, Hadaya K, Enriquez N, Meylan P, Froissart M, Golshayan D, Fehr T, Huynh-Do U, Pascual M, Van Delden C, Hirsch H, Jüni P, Müller N, Swiss Transplant Cohort Study (STCS). Immune monitoring-guided vs fixed duration of antiviral prophylaxis against cytomegalovirus in solid-organ transplant recipients. A Multicenter, Randomized Clinical Trial. Clin Infect Dis 2023

Type

Journal Paper/Review (English)

Journal

Clin Infect Dis 2023

Publication Date

Sep 22, 2023

Issn Electronic

1537-6591

Brief description/objective

The use of assays detecting cytomegalovirus (CMV)-specific T-cell-mediated immunity may individualize the duration of antiviral prophylaxis in transplant recipients.