Tonic-clonic activity at subarachnoid hemorrhage onset: impact on complications and outcome.

Publication

Tonic-clonic activity at subarachnoid hemorrhage onset: impact on complications and outcome.

Journal Paper/Review - Aug 12, 2013

De Marchis Gian Marco, Pugin Deborah, Lantigua Hector, Zammit Christopher, Tadi Prasanna, Sanchez Schmidt J M, Falo M Cristina, Agarwal Sachin, Mayer Stephan A, Claassen Jan

Citation

De Marchis G, Pugin D, Lantigua H, Zammit C, Tadi P, Sanchez Schmidt J, Falo M, Agarwal S, Mayer S, Claassen J. Tonic-clonic activity at subarachnoid hemorrhage onset: impact on complications and outcome. PloS one 2013; 8:e71405.

Type

Journal Paper/Review (English)

Journal

PloS one 2013; 8

Publication Date

Aug 12, 2013

Issn Electronic

1932-6203

Pages

e71405

Brief description/objective

Tonic-clonic activity (TCA) at onset complicates 3% to 21% of cases of subarachnoid hemorrhage (SAH). The impact of onset TCA on in-hospital complications, including seizures, remains unclear. One study associated onset TCA with poor clinical outcome at 6 weeks after SAH, but to our knowledge no other studies have confirmed this relationship. This study aims to assess the impact of onset TCA on in-hospital complications, poor functional outcome, mortality, and epilepsy at 3 months.