Is pentobarbital safe and efficacious in the treatment of super-refractory status epilepticus: a cohort study.

Publication

Is pentobarbital safe and efficacious in the treatment of super-refractory status epilepticus: a cohort study.

Journal Paper/Review - May 21, 2014

Pugin Deborah, Foreman Brandon, De Marchis Gian Marco, Fernandez Andres, Sanchez Schmidt J M, Czeisler Barry M, Mayer Stephan A, Agarwal Sachin, Lesch Christine, Lantigua Hector, Claassen Jan

Citation

Pugin D, Foreman B, De Marchis G, Fernandez A, Sanchez Schmidt J, Czeisler B, Mayer S, Agarwal S, Lesch C, Lantigua H, Claassen J. Is pentobarbital safe and efficacious in the treatment of super-refractory status epilepticus: a cohort study. Crit Care 2014; 18:R103.

Type

Journal Paper/Review (English)

Journal

Crit Care 2014; 18

Publication Date

May 21, 2014

Issn Electronic

1466-609X

Pages

R103

Brief description/objective

Seizures refractory to third-line therapy are also labeled super-refractory status epilepticus (SRSE). These seizures are extremely difficult to control and associated with poor outcome. We aimed to characterize efficacy and side-effects of continuous infusions of pentobarbital (cIV-PTB) treating SRSE.