Serum S-100B adds incremental value for the prediction of symptomatic intracranial hemorrhage and brain edema after acute ischemic stroke.

Publication

Serum S-100B adds incremental value for the prediction of symptomatic intracranial hemorrhage and brain edema after acute ischemic stroke.

Journal Paper/Review - Dec 21, 2022

Honegger Tim, Schweizer Juliane, Bicvic Antonela, Westphal Laura Philine, Schütz Valerie, Inauen Corinne, Pokorny Thomas, Bracher Katja, Arnold Marcel, Fischer Urs, Bonati Leo H, De Marchis Gian Marco, Nedeltchev Krassen, Kahles Timo, Cereda Carlo W, Kägi Georg, Montaner Joan, Bustamante Alejandro, Palà Elena, Ntaios Georges, Foerch Christian, Luft Andreas R, Spanaus Katharina, Saleh Lanja, von Eckardstein Arnold, Arnold Markus, Katan Mira

Citation

Honegger T, Schweizer J, Bicvic A, Westphal L, Schütz V, Inauen C, Pokorny T, Bracher K, Arnold M, Fischer U, Bonati L, De Marchis G, Nedeltchev K, Kahles T, Cereda C, Kägi G, Montaner J, Bustamante A, Palà E, Ntaios G, Foerch C, Luft A, Spanaus K, Saleh L, von Eckardstein A, Arnold M, Katan M. Serum S-100B adds incremental value for the prediction of symptomatic intracranial hemorrhage and brain edema after acute ischemic stroke. Eur Stroke J 2022; 8:309-319.

Type

Journal Paper/Review (English)

Journal

Eur Stroke J 2022; 8

Publication Date

Dec 21, 2022

Issn Electronic

2396-9881

Pages

309-319

Brief description/objective

Early identification of patients developing symptomatic intracranial hemorrhage and symptomatic brain edema after acute ischemic stroke is essential for clinical decision-making. Astroglial protein S-100B is a marker of blood-brain barrier disruption, which plays an important role in the formation of intracranial hemorrhage and brain edema. In this study, we assessed the prognostic value of serum S-100B for the development of these complications.