Both tadalafil and dexamethasone may reduce the incidence of high-altitude pulmonary edema: a randomized trial.

Publication

Both tadalafil and dexamethasone may reduce the incidence of high-altitude pulmonary edema: a randomized trial.

Journal Paper/Review - Oct 3, 2006

Maggiorini Marco, Brunner-La Rocca Hans-Peter, Peth Simon, Fischler Manuel, Böhm Thomas, Bernheim Alain, Kiencke Stefanie, Bloch Konrad E, Dehnert Christoph, Naeije Robert, Lehmann Thomas, Bärtsch Peter, Mairbäurl Heimo

Citation

Maggiorini M, Brunner-La Rocca H, Peth S, Fischler M, Böhm T, Bernheim A, Kiencke S, Bloch K, Dehnert C, Naeije R, Lehmann T, Bärtsch P, Mairbäurl H. Both tadalafil and dexamethasone may reduce the incidence of high-altitude pulmonary edema: a randomized trial. Ann Intern Med 2006; 145:497-506.

Type

Journal Paper/Review (English)

Journal

Ann Intern Med 2006; 145

Publication Date

Oct 3, 2006

Issn Electronic

1539-3704

Pages

497-506

Brief description/objective

High-altitude pulmonary edema (HAPE) is caused by exaggerated hypoxic pulmonary vasoconstriction associated with decreased bioavailability of nitric oxide in the lungs and by impaired reabsorption of alveolar fluid.