Respiratory bronchiolitis-interstitial lung disease: A rare complication of smoking

Publication

Respiratory bronchiolitis-interstitial lung disease: A rare complication of smoking

Journal Paper/Review - Jul 15, 2022

Isic Elmina, Rassouli Frank, Rodriguez Regulo, Kluckert Jörg-Thomas, Brutsche Martin

Units

Pneumologie und Schlafmedizin, Pathologie, Radiologie und Nuklearmedizin

Keywords

Bilateral miliary; CT; Tuberculosis; Lung

Link

https://www.researchgate.net/publication/362230747_Open_Journal_of_Clinical_Medical_Respiratory_bronchiolitis-interstitial_lung_disease_A_rare_complication_of_smoking

Contact

Jörg-Thomas Kluckert

Citation

Isic E, Rassouli F, Rodriguez R, Kluckert J, Brutsche M. Respiratory bronchiolitis-interstitial lung disease: A rare complication of smoking. Open Journal of Clinical & Medical Case Reports 2022; 8 (2022)

Type

Journal Paper/Review (English)

Journal

Open Journal of Clinical & Medical Case Reports 2022; 8 (2022)

Publication Date

Jul 15, 2022

Issn Electronic

2379-1039

Brief description/objective

A 58-year-old male and a 52-year-old female, both active smokers, presented an incidental finding of bilateral miliary, centrilobular, diffuse ground glass-like opacities on their chest CT. The differential diagnosis
is broad and includes miliary tuberculosis and vasculitis and could be ruled out after bronchoalveolar lavage and transbronchial biopsies. Lung cryobiopsy revealed interstitial and intraalveolar accumulation of
brownish pigmented alveolar macrophages with small, fine-granular, anthracotic particles, i.e. “smokers
macrophages”. The diagnosis of bronchiolitis-interstitial lung disease was retained at the institutional multidisciplinary ILD-board. Partial and complete remission was observed after smoking cessation.