Publication
Update Breast Cancer 2020 Part 4 - Advanced Breast Cancer
Journal Paper/Review - Nov 6, 2020
Tesch Hans, Luftner Diana, Schneeweiss Andreas, Lux Michael P, Fehm Tanja N, Overkamp Friedrich, Welslau Manfred, Schulmeyer Carla E, Kolberg Hans-Christian, Fasching Peter A, Huober Jens, Thill Marc, Hartkopf Andreas, Schütz Florian, Belleville Erik, Ettl Johannes, Wöckel Achim, Müller Volkmar, Janni Wolfgang
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Brief description/objective
Substances with good effectiveness that intervene in specific signalling pathways have been used increasingly in recent years in the treatment of patients with advanced breast cancer, and new therapies and approaches have now been added, which actually relate to quite specific changes, such as the treatment of patients with HR+/HER2 tumours with a mutation. The treatment of patients with a or mutation has also been improved by the introduction of PARP inhibitors. Attempts are now being made increasingly to extend treatment indications based on molecular patterns, to identify other patients who could benefit from a treatment and to integrate the newly established treatment methods in existing therapy sequences. This review articles summarises the latest information in this connection.