Publication
Feasibility and Safety of Cerebral Embolic Protection Device Insertion in Bovine Aortic Arch Anatomy
Journal Paper/Review - Dec 20, 2020
Tagliari Ana Paula, Maisano Francesco, Blöchlinger Stefan, Khattab Ahmed Aziz, Jörg Lucas, Gennari Marco, Gavazzoni Mara, Vicentini Luca, Schmiady Martin Oliver, Haager Philipp K., Ferrari Enrico, Taramasso Maurizio
Units
PubMed
Doi
Citation
Type
Journal
Publication Date
Issn Print
Brief description/objective
BACKGROUND
Cerebral embolic protection devices (CEPDs) have emerged as a mechanical barrier to prevent debris from reaching the cerebral vasculature, potentially reducing stroke incidence. Bovine aortic arch (BAA) is the most common arch variant and represents challenge anatomy for CEPD insertion during transcatheter aortic valve replacement (TAVR).
METHODS
Cohort study reporting the Sentinel Cerebral Protection System insertion's feasibility and safety in 165 adult patients submitted to a transfemoral TAVR procedure from April 2019 to April 2020. Patients were divided into 2 groups: (1) BAA; (2) non-BAA.
RESULTS
Median age, EuroScore II, and STS score were 79 years (74-84), 2.9% (1.7-6.2), and 2.2% (1.6-3.2), respectively. BAA was present in 12% of cases. Successful two-filter insertion was 86.6% (89% non-BAA vs. 65% BAA; = 0.002), and debris was captured in 95% (94% non-BAA vs. 95% BAA; = 0.594). No procedural or vascular complications associated with Sentinel insertion and no intraprocedural strokes were reported. There were two postprocedural non-disabling strokes, both in non-BAA.
CONCLUSION
This study demonstrated Sentinel insertion feasibility and safety in BAA. No procedural and access complications related to Sentinel deployment were reported. Being aware of the bovine arch prevalence and having the techniques to navigate through it allows operators to successfully use CEPDs in this anatomy.