Publication
Integrative population pharmacokinetic and pharmacodynamic dose finding approach of the new camptothecin compound namitecan (ST1968).
Journal Paper/Review - Jun 3, 2015
Joerger M, Hess D, Delmonte Angelo, Gallerani E, Fasolo A, Gianni L, Cresta S, Barbieri P, Pace S, Sessa C
Units
PubMed
Doi
Contact
Citation
Joerger M, Hess D, Delmonte A, Gallerani E, Fasolo A, Gianni L, Cresta S, Barbieri P, Pace S, Sessa C. Integrative population pharmacokinetic and pharmacodynamic dose finding approach of the new camptothecin compound namitecan (ST1968). Br J Clin Pharmacol 2015; 80:128-38.
Type
Journal Paper/Review (English)
Journal
Br J Clin Pharmacol 2015; 80
Publication Date
Jun 3, 2015
Issn Electronic
1365-2125
Pages
128-38
Brief description/objective
Namitecan is a new camptothecan compound undergoing early clinical development. This study was initiated to build an integrated pharmacokinetic (PK) and pharmacodynamic (PD) population model of namitecan to guide future clinical development.