Projects
Search from 1133 projects:
410 Project(s)
Oceanic AF
Jun 1, 2023A multicenter, international, randomized, active comparator-controlled, double-blind, doubledummy, parallel-group, 2-arm, Phase 3 study to compare the efficacy and safety of the oral FXIa inhibitor asundexian (BAY 2433334) with apixaban for the preve...
Clinical Studies - Jun 1, 2023 - Jun 30, 2024
Completed
Project leader: Rickli Hans
Members: Fink Karin, Vetsch Susanne
AMGEN202100057
May 1, 2022A Multicenter, Cross-sectional Study to Characterize the Distribution of Lipoprotein(a) Levels Among Patients With Documented History of Atherosclerotic Cardiovascular Disease (ASCVD). The purpose of the study is to characterize the distribution o...
Clinical Studies - May 1, 2022 - Mar 31, 2023
Completed
Project leader: Rickli Hans
Members: Vetsch Susanne, Bilz Stefan, Räss Andrea
ADDRESS
Mar 25, 2022Weight Loss and Treatment Patterns in a Real-World Population of Adults Receiving Saxenda® for Weight Management in Routine Clinical Practice in Switzerland
Clinical Studies - Mar 25, 2022 - Jun 30, 2022
Completed
Project leader: Aczel Stefan
Members: Räss Andrea
BMS_IM101-863
Jan 24, 2022A Phase 3, Randomized, Head-to-head, Single-blind Study to Compare the Response to Treatment with Subcutaneous Abatacept vs Adalimumab, on Background Methotrexate, in Adults with Early, Seropositive Rheumatoid Arthritis Who Have "Shared Epitope" HLA...
Clinical Studies - Jan 24, 2022 - Jan 17, 2025
Completed
Project leader: Rubbert-Roth Andrea
Members: Peischl Shirin, Peischl Riana, Bartz-Batliner Mira, Haller Christoph, Pirker Ian, Hutz Carina Liane
Long-term outcome evaluation of Interdisciplinary Multimodal Pain Therapy (IMPT) on Insomnia: A retrospective analysis of patients with chronic pain at the Cantonal Hospital St.Gallen (Switzerland)
Jan 1, 2022Objectives / Introduction: Chronic pain, in contrast to acute pain, has lost his tissue-danger-signalling property and may cause suffering, loss of function and decrease in quality of life (QoL). Patients with chronic pain often suffer from poor slee...
Clinical Studies - Jan 1, 2022 - Dec 31, 2022
Completed
Project leader: Schmid Dagmar, Oeltjenbruns Jochen
Members: Elbs Klaus, Germann Nicolas
Wirksamkeit von Gruppenpsychotherapie bei Narkolepsie Typ 1
Oct 1, 2021Narkolepsie ist eine seltene schwere chronische neurologische Erkrankung des Schlaf-Wach-Systems, die meist junge Menschen betrifft. Klinisch werden zwei Formen unterschieden: Narkolepsie mit/ohne Kataplexien, bzw. Narkolepsie Typ 1 (mit Kataplexien;...
Clinical Studies - Oct 1, 2021 - Oct 31, 2022
Completed
Project leader: Schmid Dagmar
Members: Reiss Verena, Gehrig Cornelius, Germann Nicolas, Von Manitius Sigrid
Efficacy and safety comparison of brodalumab versus guselkumab in adult subjects with moderate -to -severe plaque psoriasis and inadequate response to ustekinumab; COBRA / Phase 4 – efficacy trial A randomised, blinded, parallel-group, multi-site, clinical trial
Sep 13, 2021
Clinical Studies - Sep 13, 2021 - Nov 16, 2022
Completed
Project leader: Cozzio Antonio
SAKK 67/20 Open-label single-stage phase 1B study of the new micellar docetaxel compound Docecal in patients with advanced castra-tion-resistant prostate cancer
May 28, 2021Background: Docetaxel, a semi-synthetic analogue of paclitaxel, is one of the most widely used human anti-cancer agents. Docetaxel and paclitaxel belong to a group of cytotoxic agents called tax-anes. Docetaxel has been marketed worldwide by Sanofi-...
Clinical Studies - May 28, 2021 - Dec 31, 2024
Completed
Project leader: Fischer Stefanie
Members: Aeschbacher Anette, Frehner Jan
Pilot study on cognitive and social function measures for early detection of progressive neurocognitive disorders in Switzerland
May 12, 2021
Clinical Studies - May 12, 2021 - Sep 15, 2022
Completed
Project leader: Felbecker Ansgar
Response to COVID-19 vaccination and COVID-19 infections after vaccination in patients with haematological malignancies
May 1, 2021The prevalence and mortality of COVID-19 are higher in patients with haematological malignancies (HM) compared to the general population (Vijenthira et al. 2020). Two SARS-CoV-2 messenger RNA (mRNA) vaccines have been approved by Swissmedic, both are...
Clinical Studies - May 1, 2021 - Oct 1, 2022
Completed
Project leader: Silzle Tobias
Members: Fischer Stefanie, Kahlert Christian, Albrich Werner
An open-label Phase 1/2a study of oral BAL101553
Mar 8, 2021Frühe Phase-II Studie zur Behandlung von IDH-Wildtyp Glioblastomen oder IDH-mutierten Astrozytomen WHO Grad IV nach Progression (jede Linie) mit Lisavanbulin als orale Monotherapie mit geringen Nebenwirkungen. Die Wirksamkeit der Behandlung mit Lisav...
Clinical Studies - Mar 8, 2021 - Feb 16, 2030
Completed
Project leader: Hundsberger Thomas
I6T-MC-AMBI
Feb 1, 2021A Phase 3b, Randomized, Double-Blind, Parallel-Arm, Placebo- and Active- Controlled Treat-Through Study of Mirikizumab and Vedolizumab in participants with Moderately to Severely Active Ulcerative Colitis
Clinical Studies - Feb 1, 2021 - Jan 1, 2024
Completed
Project leader: Brand Stephan
Members: Smolders Jolijn, Krieger-Grübel Claudia
RECOVER: Rheumatoid Covid-19 Vaccine Immune Response
Feb 1, 2021Untersuchung der Sicherheit und Effektivität von mRNA basierten COVID-19 Impfungen bei Patienten mit rheumatoider Arthritis - ein exploratives Forschungsprojekt
Clinical Studies - Feb 1, 2021 - Dec 31, 2022
Completed
Project leader: Rubbert-Roth Andrea
Members: Schmiedeberg Kristin, Bartz-Batliner Mira, Peischl Riana, Peischl Shirin, Sasselli Clelia, Hutz Carina Liane
Translation of pre-treatment tumor kinetics and clinical and serological markers of the immune system in the treatment of advanced melanoma
Jan 1, 2021Bei diesem Projekt geht es um die Charakterisierung des Therapieansprechens von Melanommetastasen unter Systemtherapie mit anti-PD-1 Antikörpern, kombinierter Immuntherapie mit dem anti-PD-1 Antikörper Nivolumab und dem anti-CTLA-4 Antikörper Ipilimu...
Clinical Studies - Jan 1, 2021 - Dec 31, 2021
Completed
Project leader: Wagner Nikolaus
Validation of COVID-19 risk stratification algorithms based on sTREM-1 and IL-6 in Emergency Departments: a retrospective multicenter cohort study
Dec 1, 2020We will retrospectively select SARS-CoV-2 infected adults who attended the ED of St.Gallen and Bellinzona. We want to measure the concentrations from stored blood samples of: Biomarkers of immune dysfunction: e.g., C reactive protein, procalciton...
Clinical Studies - Dec 1, 2020 - Apr 28, 2023
Completed
Project leader: Albrich Werner
IFX-1-P2.5
Nov 1, 2020a randomized, double-blind, double-dummy, active-controlled, multicenter, 2-part Phase 2 study on replacement of steroids by IFX-1 in active granulomatosis with polyangiitis (GPA) and microscopic polyangitis (MPA)
Clinical Studies - Nov 1, 2020 - Nov 1, 2021
Completed
Project leader: Neumann Thomas
Members: Peischl Riana, Rubbert-Roth Andrea
APD334-206 Etrasimod
Oct 1, 2020A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study to Assess the Safety and Efficacy of Etrasimod in Adult Subjects with Eosinophilic Esophagitis
Clinical Studies - Oct 1, 2020 - Dec 1, 2022
Completed
Project leader: Brand Stephan, Smolders Jolijn
Biogen c9ORF 245AS102
Sep 1, 2020Eine Verlängerungsstudie zur Beurteilung von Langzeitsicherheit, Verträglichkeit, Pharmakokinetik und Wirkung auf das Fortschreiten der Erkrankung von BIIB078 bei zuvor behandelten Erwachsenen mit C9ORF72-assoziierter amyotropher Lateralsklerose
Clinical Studies - Sep 1, 2020 - Dec 31, 2024
Completed
Project leader: Weber Markus
I4V-MC-JAIM
Aug 12, 2020a phase 3, double-blind, multicenter study of evaluate the long-term safety and efficacy of baricitinib in patients with SLE.
Clinical Studies - Aug 12, 2020 - Aug 12, 2022
Completed
Project leader: Rubbert-Roth Andrea
Members: Peischl Riana, Bartz-Batliner Mira
XATOC – Xarelto + Acetylsalicylic Acid
Jul 14, 2020Treatment patterns and Outcomes across the disease Continuum in patients with CAD and/or PAD The study aims to collect real-world data on treatment patterns and decision points for treatment in patients with coronary artery disease (CAD) or sym...
Clinical Studies - Jul 14, 2020 - Apr 14, 2023
Completed
Project leader: Rickli Hans
Members: Fink Karin