Projects
Search from 1133 projects:
228 Project(s)
Muscle-invasive bladder cancer (MIBC) and perioperative treatment
May 13, 2022Diese Studie untersucht die Kombination der Standardtherapie für das muskelinvasive Blasenkarzinom (Chemotherapie gefolgt von einer Operation mit Entfernung der Harnblase) mit einer Immuntherapie mit Bacille Calmette Guérin (BCG) und Atezolizumab. BC...
Clinical Studies - May 13, 2022 - May 13, 2032
Ongoing
Project leader: Aeppli Stefanie
Members: Scherrer Julia, Frehner Jan
Treatment and outcomes of surgical site infections after spinal instrumentation – a retrospective cohort study
May 2, 2022
Clinical Studies - May 2, 2022 - Dec 31, 2024
Ongoing
Project leader: Strahm Carol
Members: Cosma Tudor, Zdravkovic Vilijam
INCMOR0208-301: A PHASE 3, RANDOMIZED, DOUBLE-BLIND, PLACEBOCONTROLLED, MULTICENTER TRIAL TO EVALUATE THE EFFICACY AND SAFETY OF TAFASITAMAB PLUS LENALIDOMIDE IN ADDITION TO RITUXIMAB VERSUS LENALIDOMIDE IN ADDITION TO RITUXIMAB IN PATIENTS WITH RELAPSED/REFRACTORY (R/R) FOLLICULAR LYMPHOMA (FL) GRADE 1-3A OR R/R MARGINA
Apr 20, 2022Doppel-blind, Placebo-kontrollierte, randomisierte Phase 3 Studie zur Evaluation eines zusätzlichen klinischen Benefits durch die Zugabe des CD19-Antikörpers Tafasitamab zu Rituximab-Lenalidomid bei Patienten mit rezidiviertem/refraktärem Follikuläre...
Clinical Studies - Apr 20, 2022 - Dec 31, 2025
Ongoing
Project leader: Fehr Martin
Members: Bürki Ramona, Frehner Jan
MitraSwiss Register
Apr 1, 2022A longitudinal observational study of patients treated with the MitraClip system in Switzerland
Register - Apr 1, 2022 - Dec 31, 2030
Ongoing
Project leader: Haager Philipp
Members: Schneider Irene
Metabotropic Glutamate Receptor 5 Imaging in Amyotrophic Lateral Sclerosis (ALS) Using Positron Emission Tomography (PET)
Mar 24, 2022Amyotrophic lateral sclerosis is a fatal neurodegenerative disorder characterized by a progressive and selective loss of upper and lower motor neurons (MNs), causing weakness and ultimately death. Glutamate excitotoxicity has been suggested to play a...
Clinical Studies - Mar 24, 2022 - Nov 30, 2025
Ongoing
Project leader: Braun Nathalie
A Phase III, randomised, Open-Label, multicenter study evaluating the efficacy and safety of adjuvant GDC-9545 compared with physician's choice of adjuvant endocrine Monotherapy in patiens with Estrogen Receptor−Positive, HER2-NegativeEarly Breat Cancer
Mar 1, 2022Der Zweck dieser Studie ist es, die positiven oder negativen Auswirkungen von Giredestrant im Vergleich zu einer zugelassenen endokrinen Therapie (eine Behandlung, die Hormone blockiert oder entfernt) bei Patientinnen/Patienten mit Ihrer Art von Kreb...
Clinical Studies - Mar 1, 2022 - Jul 26, 2030
Ongoing
Project leader: Huober Jens
Members: Sennhauser Andrina, Quinter Janine
MT-1186-A02
Feb 14, 2022Eine Studie zur Untersuchung, ob die Prüfsubstanz Edaravone, die als flüssige Lösung zum Schlucken über einen Zeitraum von 48 Wochen verabreicht wird, bei Patienten mit ALS gut wirkt und sicher ist.
Clinical Studies - Feb 14, 2022 - Dec 31, 2024
Ongoing
Project leader: Braun Nathalie
Real world utilization of upadacitinib in adult and adolescent patients living with moderate to severe atopic dermatitis (AD-VISE)
Feb 14, 2022
Clinical Studies - Feb 14, 2022 - Dec 31, 2025
Ongoing
Project leader: Cozzio Antonio
A multicenter, prospective observational RWE study to assess Patient-reported wellbeing using tildrakizumab in a live setting – POSITIVE Study
Jan 18, 2022
Clinical Studies - Jan 18, 2022 - Dec 31, 2024
Ongoing
Project leader: Saulite Ieva
A Phase 1, Open-Label, Multicenter Study to Assess Safety, Tolerability, PK, and Efficacy of MK-1084 as Monotherapy and in Combination with Pembrolizumab in Subjects with KRASG12C Mutant Advanced Solid Tumors
Jan 13, 2022MK-1084 enthält einen chemischen Wirkstoff und hemmt gezielt das mutierte KRAS-G12C-Protein. Generell spielen RAS-Proteine in der Zellteilung und Zelldifferenzierung eine grosse Rolle und wenn diese Proteine zu stark aktiviert sind, kann das zu Krebs...
Clinical Studies - Jan 13, 2022 - Mar 2, 2027
Ongoing
Project leader: Weindler Susanne
Members: Donno Monica, Quinter Janine
SOS AMI Selatogrel
Jan 10, 2022Multi-center, double-blind, randomized, placebo-controlled, parallel-group study to evaluate the efficacy and safety of self-administered subcutaneous selatogrel for prevention of all-cause death and treatment of acute myocardial infarction in subjec...
Clinical Studies - Jan 10, 2022 - Jan 14, 2026
Ongoing
Project leader: Maeder Micha
Members: Vetsch Susanne, Fink Karin
Courage-ALS
Jan 6, 2022Die Prüfsubstanz Reldesemtiv ist ein Aktivator des schnellen Skelettmuskel-Troponin-Komplexes. Die Therapie dient zur Verbesserung der Skelettmuskelfunktion bei Erkrankungen im Zusammenhang mit Muskelschwäche und/oder Muskelermüdung.
Clinical Studies - Jan 6, 2022 - Dec 31, 2024
Ongoing
Project leader: Weber Markus
Cannabinoid Receptor Imaging ALS Studie
Jan 1, 2022Vor einigen Jahren wurde entdeckt, dass das Endocannabinoid-System bei der Pathogenese der ALS eine Rolle spielt. Die Manipulation des Endocannabinoid-Systems über die Aktivierung des sogenannten Cannabinoid Rezeptors Typ 2 (CB2) in einem ALS-Tiermod...
Clinical Studies - Jan 1, 2022 - Dec 31, 2024
Ongoing
Project leader: Weber Markus
Evaluation of Post-ERCP Pain as a Predictor for Post-ERCP Pancreatitis: A Prospective Multi-Center Observational Trial
Jan 1, 2022The objective of this study is to assess whether the assessment of post-procedural pain predicts the development of PEP (either alone or in combination with other known risk factors). If this should be possible, patients at risk could be offered an...
Clinical Studies - Jan 1, 2022 - Dec 31, 2024
Ongoing
Members: Frei Nicola Fabian
Tissue Cytokines at the Nexus of Immune Cell-Cardiac Stromal Cell Interaction-CardiacStroma
Jan 1, 2022
Fundamental Research - Jan 1, 2022 - Dec 30, 2026
Ongoing
Project leader: Ludewig Burkhard
Novartis CAIN457R12301
Jan 1, 2022A randomized, parallel-group, double-blind, placebo-controlled, multicenter Phase III trial to investigate the efficacy and safety of secukinumab 300 mg and 150 mg administered subcutaneously versus placebo, in combination with a glucocorticoid taper...
Clinical Studies - Jan 1, 2022 - Jan 1, 2025
Ongoing
Project leader: Rubbert-Roth Andrea
Members: Schmiedeberg Kristin, Bartz-Batliner Mira, Peischl Shirin, Gostic Dragana
Low Anterior Resection Syndrome After Rectum Resection for Rectal Carcinoma. (LARS-Austria)
Jan 1, 2022Primary objective of the LARS study is to obtain the LARS score before surgical rectal cancer treatment, after neoadjuvant therapy and during the standard follow-up after surgery. This study mainly serves to obtain statistical data for the incidence...
Clinical Studies - Jan 1, 2022 - Aug 30, 2024
Ongoing
Project leader: Presl Jaroslav, Brunner Walter
The rate of complicated appendicitis during nonpharmaceutical intervention in two different COVID-19 incidence,
Jan 1, 2022
Clinical Studies - Jan 1, 2022 - Jun 1, 2024
Ongoing
Members: Bauci Gabriele, Ukegjini Kristjan, Marti Lukas, Steffen Thomas
Partial pancreatoduodenectomy versus total pancreatectomy in patients with preoperative diabetes mellitus: Comparison of surgical outcomes and quality of life.
Jan 1, 2022
Clinical Studies - Jan 1, 2022 - Jun 1, 2024
Ongoing
Members: Ukegjini Kristjan, Warschkow Rene, Tarantino Ignazio, Schmied Bruno, Steffen Thomas
Prolonged antibiotic prophylaxis do not impact perioperative outcomes after pancreatoduodenectomy in patients with biliary stent. A Propensity Score and Mediation Analysis
Jan 1, 2022
Clinical Studies - Jan 1, 2022 - Jun 1, 2024
Ongoing
Members: Ukegjini Kristjan, Warschkow Rene, Tarantino Ignazio, Schmied Bruno, Steffen Thomas