Projects
Search from 1147 projects:
1147 Project(s)
An Open-Label, Randomized, Controlled Multi-Center Study of The Efficacy of Daromun (L19IL2 + L19TNF) Neoadjuvant Intratumoral Treatment Followed by Surgery and Adjuvant Therapy Versus Surgery and Adjuvant Therapy in Clinical Stage IIIB/C Melanoma Patients
Jul 11, 2022
Clinical Studies - Jul 11, 2022 - Dec 31, 2026
Ongoing
Project leader: Wagner Nikolaus
A Phase 1/Phase 2 Study to Evaluate the Safety and Tolerability of MK-1088 as Monotherapy and in Combination with Pembrolizumab in Participants with Advanced Solid Tumors
Jul 8, 2022Die Immuntherapie hat die Behandlung vieler Krebsraten deutlich verbessert. Tumore verfügen jedoch über mehrere Mechanismen um eine Immunantwort zu begrenzen oder der Immunüberwachung zu entgehen. Diese Studie untersucht neuartige Wege, diese Barrier...
Clinical Studies - Jul 8, 2022 - Dec 31, 2025
Ongoing
Project leader: Hess Dagmar
Members: Aeschbacher Anette, Quinter Janine
Two cohort registry study for patients with advanced CSCC treated with Cemiplimab or other approaches
Jul 1, 2022
Clinical Studies - Jul 1, 2022 - Dec 31, 2025
Ongoing
Project leader: Wagner Nikolaus
Genetic contributors of multiple myeloma cells involved in their homing and escape from T-cell recognition
Jul 1, 2022Finding highly active treatment for patients with relapsed/refractory multiple myeloma is an unmet clinical need. The immune-based treatment approaches in this population of patients have shown notable anti-myeloma activity, with deeper and durable r...
Fundamental Research - Jul 1, 2022 - Jun 30, 2023
Automatically Closed
Project leader: Besse Lenka
Members: Besse Andrej
Fibroblastendifferenzierung und -funktion im Tonsillenkarzinom
Jun 24, 2022
Fundamental Research - Jun 24, 2022 - Dec 31, 2023
Automatically Closed
Project leader: Ludewig Burkhard
Members: Meili Samuel
I6T-MC-AMAX
Jun 7, 2022A Phase 3, Multicenter, Open-Label, Long-Term Extension Study to Evaluate the Long-Term Efficacy and Safety of Mirikizumab in Patients with Crohn's Disease
Clinical Studies - Jun 7, 2022 - Dec 31, 2024
Ongoing
Project leader: Brand Stephan
Members: Eckhold Annika, Krieger-Grübel Claudia, König Marius
CDED Ernährungsstudie
Jun 1, 2022The Crohn’s disease exclusion diet (CDED) for induction and maintenance of remission in Crohn’s patients with or without additional medical therapy. An open label observational trial
Clinical Studies - Jun 1, 2022 - Dec 30, 2023
Automatically Closed
Project leader: Krieger-Grübel Claudia
Members: Brand Stephan, Eckhold Annika
CED-4/CEL
Jun 1, 2022This is a double-blind, randomised, multicentre, placebo-controlled, comparative phase IIb dose-finding and efficacy trial. The trial will be conducted with four treatment groups in the form of a parallel group comparison and will serve to compare...
Clinical Studies - Jun 1, 2022 - Dec 31, 2024
Ongoing
Project leader: Brand Stephan
Members: Eckhold Annika, König Marius, Krieger-Grübel Claudia, Truniger Samuel
Retinale endotheliale Dysfunktion bei Raynaud-Phänomen
Jun 1, 2022Untersuchung der Endothelfunktion retinaler Gefässe bei Patienten mit einem Raynaud Phänomen mit dem Ziel, Veränderungen im Vergleich zu gesunden Menschen darzustellen und Beziehungen zwischen Parametern der retinalen Endothelfunktion, der Kapillarmi...
Clinical Studies - Jun 1, 2022 - Jun 30, 2025
Ongoing
Project leader: Neumann Thomas
Members: Todorova Margarita, Güsewell Sabine
SAKK 06/19 Intravesical recombinant BCG followed by perioperative chemo-immunotherapy for patients with muscleinvasive bladder cancer (MIBC).A multicenter, single-arm phase II trial
May 13, 2022Verbesserung der kurativen Therapie des muske-linvasiven Urothelkarzinoms. Durch den Einsatz von BCG lokal in der Blase und perioperativer Immuno-Chemotherapie soll die Ansprechrate verbessert werden
Clinical Studies - May 13, 2022 - Jul 26, 2030
Ongoing
SAKK 06/19 Intravesical recombinant BCG followed by perioperative chemo-immunotherapy for patients with muscleinvasive bladder cancer (MIBC).A multicenter, single-arm phase II trial
May 13, 2022Verbesserung der kurativen Therapie des muske-linvasiven Urothelkarzinoms. Durch den Einsatz von BCG lokal in der Blase und perioperativer Immuno-Chemotherapie soll die Ansprechrate verbessert werden
Clinical Studies - May 13, 2022 - Jul 26, 2030
Ongoing
SAKK 06/19 Intravesical recombinant BCG followed by perioperative chemo-immunotherapy for patients with muscleinvasive bladder cancer (MIBC).A multicenter, single-arm phase II trial
May 13, 2022Verbesserung der kurativen Therapie des muske-linvasiven Urothelkarzinoms. Durch den Einsatz von BCG lokal in der Blase und perioperativer Immuno-Chemotherapie soll die Ansprechrate verbessert werden
Clinical Studies - May 13, 2022 - Jul 26, 2030
Ongoing
Muscle-invasive bladder cancer (MIBC) and perioperative treatment
May 13, 2022Diese Studie untersucht die Kombination der Standardtherapie für das muskelinvasive Blasenkarzinom (Chemotherapie gefolgt von einer Operation mit Entfernung der Harnblase) mit einer Immuntherapie mit Bacille Calmette Guérin (BCG) und Atezolizumab. BC...
Clinical Studies - May 13, 2022 - May 13, 2032
Ongoing
Project leader: Aeppli Stefanie
Members: Scherrer Julia, Müller Fiona
Fluorescence-based rapid diagnostic tool for sensitive and selective Detection Of uReaSeproducing bacTEria causing ventilator-associated Pneumonia - DOORSTEP
May 2, 2022
Fundamental Research - May 2, 2022 - May 1, 2023
Automatically Closed
Project leader: Giovannini G
Members: Kahlert Christian, Nigg Susanne
Treatment and outcomes of surgical site infections after spinal instrumentation – a retrospective cohort study
May 2, 2022
Clinical Studies - May 2, 2022 - Dec 31, 2024
Ongoing
Project leader: Strahm Carol
Members: Cosma Tudor, Zdravkovic Vilijam
GO SOAR1 - Post-Operative Morbidity and Mortality Following Gynaecological Oncology Surgery
May 1, 2022Ziel dieser multizentrischen Studie ist es, die Versorgungsqualität und Komplikationsrate in der gynäkologischen Onkologie weltweit darzustellen. Hierfür werden die perioperativen Daten gynäkoonkologischer Patientinnen anonymisiert erfasst und die...
Healthcare Research - May 1, 2022 - Dec 31, 2023
Automatically Closed
Project leader: Gaba F, Fischer Marc
AMGEN202100057
May 1, 2022A Multicenter, Cross-sectional Study to Characterize the Distribution of Lipoprotein(a) Levels Among Patients With Documented History of Atherosclerotic Cardiovascular Disease (ASCVD). The purpose of the study is to characterize the distribution o...
Clinical Studies - May 1, 2022 - Mar 31, 2023
Completed
Project leader: Rickli Hans
Members: Vetsch Susanne, Bilz Stefan, Räss Andrea
Korrekturosteotomie des distalen Radius mit palmarer winkelstabiler Plattenosteosynthese ohne Knochengraft und ohne kortikalen Kontakt
May 1, 2022
Clinical Studies - May 1, 2022 - Dec 31, 2022
Automatically Closed
Project leader: Fuchs Johannes
Management of in-water traumatic spinal cord injury: an international practical consensus-based guideline
Apr 26, 2022
Register - Apr 26, 2022 - Dec 31, 2024
Automatically Closed
Project leader: Maschmann Christian
Members: Breindahl Niklas, Bierens Joost
Amgen Efavaleukin Alfa
Apr 25, 2022A Phase 2, Multicenter, Dose-finding, Double blinded, Pla-cebo- Controlled Study to Evaluate the Safety and Effi-cacy of Efavaleukin Alfa Induc-tion Therapy in Patients with Mederatly to Severely UC
Clinical Studies - Apr 25, 2022 - Dec 31, 2023
Automatically Closed
Project leader: Brand Stephan
Members: Eckhold Annika, Krieger-Grübel Claudia