Projects
Search from 1147 projects:
1147 Project(s)
MULTIPRAC Register
Nov 2, 2011MULTInationale Nicht-interventionelle Studie an Patienten mit Myokardinfarkt mit ST-Segment-Erhöhung, die mit Primärer Angioplastie und gleichzeitiger Anwendung von Antithrombozyten-Therapie mit einem Thienopyridin-Mittel (MULTIPRAC) behandelt werden
Clinical Studies - Nov 2, 2011 - Jun 19, 2014
Completed
Project leader: Rickli Hans
Members: Gemperle Michaela, Schneider Irene
Multinationale, randomisierte, doppelblinde, placebo-kontrollierte einjährige Studie zur Überprüfung der Gewichtsreduktion (40 Wochen) und Gewichtsstabilisation (12 Wochen), sowie die Entwicklung des Taillenumfangs mit Polyglucosamin L112 im Vergleich zu Placebo bei Patienten mit Übergewicht und Adipositas unter geändertem Essverhalten mit täglich bis zu 80 g Fett und gesteigerter körperlicher Aktivität
Nov 1, 2011Die WHO hat kürzlich festgestellt, dass eine Milliarde Menschen weltweit zu dick sind. Besonders die viszerale Adipositas hat ein ausgeprägtes Risikoprofil bezüglich kardio-vaskulärer Folgeerkrankungen. Bei den in dieser Studie genutzten Therapieregi...
Clinical Studies - Nov 1, 2011 - Oct 31, 2012
Aborted
Project leader: Schultes Bernd
Members: Wilms Britta, Ullrich Jennifer
Polyvalent vaccine against Salmonellosis
Nov 1, 2011The major aim of this project is to generate a polyvalent vaccine candidate using microencapsulates Salmonella typhi proteins for oral administration. To this end, the laboratory in Mexico will produce sufficient amounts of S. typhi porins for encaps...
Fundamental Research - Nov 1, 2011 - Apr 30, 2013
Completed
Project leader: Ludewig Burkhard
Members: Pérez Shibayama Christian Ivan, Gil Cruz Cristina
Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Evaluate the Efficacy, Safety & Tolerability of Two Doses of ACT-128800, an Oral S1P1 Receptor Agonist, Administered up to Twenty-eight Weeks in Patients With Moderate to Severe Chronic Plaque Psoriasis
Oct 19, 2011This study will assess the efficacy, safety and tolerability of two doses of ACT 128800 in patients with moderate-to-severe chronic plaque psoriasis.
Clinical Studies - Oct 19, 2011 - Sep 19, 2012
Automatically Closed
Project leader: Anliker Mark
Systematic Literature Review Population and Outcomes of Clinical Trials in Cachexia
Sep 26, 2011
Clinical Studies - Sep 26, 2011 - Sep 26, 2014
Completed
Project leader: Strasser Florian
Members: Wilm Simone
Contrast Recognition in Brilliant Blue G and Indoyanine Green assisted Chromovitrectomy
Sep 14, 2011To evaluate the potential of intra-operative light filters to enhance perceivable contrast following intra-operative Bril-liant Blue G (BBG) staining of the internal limiting mem-brane (ILM).
Clinical Studies - Sep 14, 2011 - Oct 31, 2013
Completed
Project leader: Valmaggia Christophe
Phase II study to investigate the efficacy of panitumumab in platinum-resistant advanced head and neck squamous cancer
Sep 3, 2011Head & Neck Tumoren sind seltene Tumoren, bei welchen leider wenige aktive Substanzen bestehen. Im Sinne der guten Verträglichkeit und in einem Zweitliniensetting macht es Sinn diese Substanz zu testen. Umso mehr, dass es auch darum geht die Patiente...
Clinical Studies - Sep 3, 2011 - Oct 31, 2012
Automatically Closed
Project leader: Siano Marco
Members: Früh Martin
Europäische Studie über die Symptome von Palliative Care Patienten (EPCCS) – Eine prospektive Datensammlung EKSG 11/072
Sep 1, 2011Patienten mit einer fortgeschrittenen bösartigen Tumorerkrankung entwickeln im Laufe der Erkrankung verschiedenste Beschwerden oder Symptome, die eine wechselnde Stärke zeigen. Schmerzen, Müdigkeit, Übelkeit und Erbrechen, Atemnot, Verstopfung, Appet...
Clinical Studies - Sep 1, 2011 - May 31, 2012
Completed
Project leader: Strasser Florian
St. Gallen Lung Biopsy Biobank - An interdisciplinary collaboration in pulmonary medicine
Sep 1, 2011The current project proposes to create a tissue and blood sample collection (biobank) of all patients willing to give informed consent, who are undergoing bronchoscopy and/or surgical lug resection in their diagnostic pathway for any pulmonary diseas...
Fundamental Research - Sep 1, 2011 - Dec 31, 2030
Automatically Closed
Project leader: Brutsche Martin
Members: Baty Florent
Retrospektive Analyse klinisch erhobener Ergospirometrie- und Lungenfunktionsdaten vor und nach bariatrischer Chirurgie
Sep 1, 2011Hintergrund: Adipositas geht häufig mit einer Einschränkung der kardiopulmonalen Leistungsfähigkeit einher. Es ist aber bislang weitgehend unbekannt, wie sich ein ausgeprägter Gewichtsverlust, wie er typischer Weise durch eine bariatrische Operation...
Clinical Studies - Sep 1, 2011 - Dec 22, 2011
Completed
Project leader: Schultes Bernd
Members: Wilms Britta
multicenter, double-blind, placebo-controlled, parallel-group, phase IV study to assess the effect of Rotigotine on non-motor symptoms in patients with idiopathic parkinson's disease
Sep 1, 2011Multizentrische, doppelblinde, placebokontrollierte Parallelgruppenstudie der Phase IV zur Bestimmung der Wirkung von Rotigotin auf die nichtmotorischen Symptome bei Patienten mit idiopathischem Parkinson-Syndrom Studie SP0976
Clinical Studies - Sep 1, 2011 - Dec 31, 2012
Automatically Closed
Project leader: Tettenborn Barbara
Members: Kägi Georg, Brugger Florian, Hägele-Link Stefan
A phase III double-blind, extension, placebo-controlled parallel group safety and efficacy trial of BI 10773 (10 and 25mg once daily) and sitagliptin (100mg once daily) given for minimum76 weeks (incl. 24 weeks of preceding trial) as monotherapy or with different back-ground therapies in patients with type 2 diabetes mellitus previously completing trial 1245.19, 1245.20 or 1245.23
Aug 25, 2011BI 10773 is an orally available inhibitor of the sodium-glucose co-transporter 2 (SGLT-2), that promotes enhanced glucose excretion in the urine, thereby lowering blood glucose concentrations in patients with type 2 diabetes mellitus (T2DM). 1.1 MEDI...
Clinical Studies - Aug 25, 2011 - Jan 1, 2013
Completed
Project leader: Schultes Bernd
Members: Ernst Barbara
An open-label, randomized, parallel group study of patients treated with Paclitaxel with standard dosing versus pharmacokinetic guided dose adjustment in patients with advanced NSCLC
Aug 10, 2011Dies ist eine offene, randomisierte, multizentrische Studie im Parallelgruppendesign, die evaluieren soll, ob eine individuell angepasste Dosierung von Paclitaxel (Arm B) Paclitaxel abhängige Grad 4 Neutropenie reduziert im Vergleich zur konventionel...
Clinical Studies - Aug 10, 2011 - Jun 30, 2012
Completed
Project leader: Jörger Markus
Members: Früh Martin, Siano Marco
Effect of liraglutide on body weight in non-diabetic obese subjects or overweight subjects with comorbidities A randomised, double-blind, placebo controlled, parallel group, multi-centre, multinational trial with stratification of subject to either 56 or 160 weeks of treatment based on pre-diabetes status at randomisation
Aug 1, 2011Primary objectives: To establish the efficacy of 3.0 mg liraglutide compared to liraglutide placebo in inducing and maintaining weight loss over 56 weeks in obese subjects and overweight subjects with comorbidities. To investigate the long term effic...
Clinical Studies - Aug 1, 2011 - Jul 31, 2014
Automatically Closed
Project leader: Schultes Bernd, Bilz Stefan
Members: Ullrich Jennifer
Vitamin C Hauptstudie
Aug 1, 2011Vitamin C und Arthrofibrose im Kniegelenk – reduziert die perioperative Vitamin C Substitution das Arthrofibroserisiko nach Implantation eines künstlichen Kniegelenkes?
Clinical Studies - Aug 1, 2011 - Dec 31, 2014
Automatically Closed
Project leader: Behrend Henrik
Members: Lengnick Harald
Prediction of early non response to anti-TNF and methotrexate combination therapy in rheumatoid arthritis patients eligible to first line anti-TNF treatment based on gene expression analysis of whole blood
Jul 25, 2011
Clinical Studies - Jul 25, 2011 - Jul 25, 2012
Completed
Project leader: Müller Rüdiger
Registerstudie CARPE-CH chronisches Handekzem
Jul 19, 2011Mit dieser Studie sollen wichtige und bisher fehlende Daten zu chronischen Handekzemen strukturiert erhoben werden, durch die neue Erkenntnisse zur Ursache, Therapie und Prognose von Handekzemen zu erwarten sind. Insbesondere sollen dadurch Erkenntni...
Clinical Studies - Jul 19, 2011 - Jul 19, 2013
Automatically Closed
Project leader: Anliker Mark
Upper Gastrointestinal Cancer metastasized to the brain – Analysis of pathological and clinical data
Jul 11, 2011BACKGROUND Metastatic upper gastrointestinal cancer is associated with a poor prognosis and the mainstay of treatement is systemic chemotherapy regardless of underlying histology. While the most frequent sites of metastatic seed are determined by th...
Fundamental Research - Jul 11, 2011 - Jul 11, 2012
Automatically Closed
Pilot study on the effect of escitalopram on cortical plasticity and glutamate transmission in healthy subjects: A neurophysiological and Magnet Resonance Spectroscopy study
Jul 1, 2011After ischemic stroke dynamic behavioral changes take place associated with different levels of recovery. Understanding the biological mechanisms that drive post-stroke recovery is of paramount clinical importance, since such knowledge could provide...
Clinical Studies - Jul 1, 2011 - May 31, 2015
Automatically Closed
Project leader: Kägi Georg
Members: Weder Bruno, Wiest Roland, Slotboom Johannes
Mechanisms of antibody-mediated protection against virus-induced inflammatory demyelination
Jul 1, 2011Background: The epidemiology of multiple sclerosis (MS) suggests that environmental factors such as infections with coronaviruses critically determine the risk for this chronic demyelinating disease. Infection of the CNS with neurotropic mouse corona...
Fundamental Research - Jul 1, 2011 - Jun 30, 2013
Completed
Project leader: Gil Cruz Cristina, Ludewig Burkhard
Members: Thiel Volker