Projects
Search from 1147 projects:
1147 Project(s)
A Phase 1/2a Dose Escalation and Cohort Expansion Study for Safety, Tolerability, and Efficacy of BMS-986156 Administered Alone and in Combination with Nivolumab (BMS-936558, anti PD-1 Monoclonal Anti-body) in Advanced Solid Tumors
Jul 21, 2016This is a Phase 1/2a, open-label study of BMS-986156 administered as a single agent and in combination with nivolumab in subjects with advanced solid tumors. The study will be conducted in 4 parts. Parts A and B will consist of dose escalation with B...
Clinical Studies - Jul 21, 2016 - Sep 30, 2017
Automatically Closed
Project leader: Jörger Markus
Immunmonitoring of patients before, during and after immunotherapy to predict anti-tumor response in melanoma and non-small cell lung cancer (IMIT)
Jul 15, 2016
Clinical Studies - Jul 15, 2016 - Oct 15, 2019
Automatically Closed
Project leader: Flatz Lukas
Members: Diem Stefan
Constructing accessory lymph nodes in situ for control of mammary carcinoma
Jul 1, 2016Lymph nodes (LNs) are situated at junctures of the blood vascular and the lymphatic system where antigens drain from peripheral tissues via afferent lymphatics. The decision whether and how immune responses against tumors are initiated and maintained...
Fundamental Research - Jul 1, 2016 - Jun 30, 2019
Automatically Closed
Project leader: Ludewig Burkhard
Members: Cupovic Jovana
A multicentre, double blind, randomised, placebo-controlled, Phase II trial to evaluate Resminostat for maintenance treatment of patients with advanced stage (Stage IIB-IVB) mycosis fungoides (MF) or Sézary Syndrome (SS) that have achieved disease control with systemic therapy – the RESMAIN Study
Jun 25, 2016
Clinical Studies - Jun 25, 2016 - Dec 31, 2027
Ongoing
Project leader: Cozzio Antonio
eSATIS: Early Sleep Apnea Treatment in Stroke: A Randomized, Rater-Blinded, Clinical Trial of Adaptive Servo-Ventilation
Jun 20, 2016The prevalence of Sleep Disordered Breathing (SDB) after acute stroke is high (over 50% of affected patients in more than 20 studies). SDB after stroke has been found to be associated with a faster progression of stroke severity, with higher blood pr...
Clinical Studies - Jun 20, 2016 - Jun 20, 2018
Automatically Closed
Project leader: Flügel Dominique
Members: Kägi Georg, Müller Anna
AdaptResponse
Jun 17, 2016Studie mit einem System für die kardiale Resynchronisationstherapie (CRT - Cardiac Resynchronization Therapy) mit der aCRT-Funktion zur optimierten Behandlung von Herzinsuffizie
Clinical Studies - Jun 17, 2016 - Dec 31, 2022
Completed
Project leader: Ammann Peter
Members: Vetsch Susanne
An Open Label Biomarker Driven Phase II Clinical Trial of Abiraterone Acetate (AA) Re-Challenge in Patients with Metastatic Castration-Resistant Prostate Cancer and Prior Response to AA (Abi-RE)
Jun 12, 2016Clinical Trial with an IMP, risk category B according to HRA. Abiraterone acetate (AA) is a standard treatment option both in chemotherapy naïve and docetaxel pre-treated men with metastatic castrate-resistant prostate cancer (CRPC). With the approva...
Clinical Studies - Jun 12, 2016 - Dec 31, 2017
Automatically Closed
Project leader: Omlin Aurelius
SAKK GRAALL 2014: Multicenter trial for the treatment of Acute Lymphoblastic Leukemia (ALL) in younger adults (18-59 years)
Jun 3, 2016GRAALL-2014 follows the GRAALL-2003 and 2005 trials. The GRAALL-2014 trial is subdivided in three sub-studies: GRAALL-2014/B, GRAALL-2014/T and GRAAPH-2014respectively for patients with B-lineage Ph-negative ALL, T-lineage ALL or Ph+ ALL. France, S...
Clinical Studies - Jun 3, 2016 - May 31, 2026
Ongoing
Project leader: Silzle Tobias
Members: Quinter Janine
A Prospective, Multicenter, Observational, Single-arm European Registry on the ACE Reperfusion Catheters and the Penumbra System in the Treatment of Acute Ischemic Stroke
Jun 2, 2016Study Objective: To observe the safety and effectiveness of the ACE Reperfusion Catheters and the Penumbra System in patients with acute ischemic stroke from large vessel occlusion, treated with the ADAPT technique in site routine practice. Study De...
Clinical Studies - Jun 2, 2016 - May 31, 2017
Completed
Members: Vehoff Jochen, Kägi Georg, Müller Anna
Longterm ureteral stenting: Assessment of stent-associated morbidity, associated costs and impact of biofilms
Jun 2, 2016Untersuchung von Biofilmen bei Patienten unter Langzeitschienung des Harnleiters. Untersuchung der assoziierten Morbidität.
Clinical Studies - Jun 2, 2016 - May 18, 2018
Automatically Closed
Project leader: Betschart Patrick
Members: Abt Dominik, Schmid Hans-Peter, Zumstein Valentin, Sauter Rafael, Staubli Sergej
FIGARO-DKD
Jun 1, 2016Diese Studie dient der Erforschung der Wirksamkeit und Sicherheit von Finineron in Ergänzung zur Standardtherapie im Hinblick auf eine Reduktion der kardiovaskulären Morbidität und Mortalität bei Patienten mit Diabetes mellitus Typ 2 mit der klinisch...
Clinical Studies - Jun 1, 2016 - Mar 31, 2021
Completed
Project leader: Bilz Stefan
Members: Jenni Vera, Dehos Barbara, Räss Andrea
SASL 40 Swiss Cohort Study on Primar Sclerosing Cholangitis
Jun 1, 2016Research project in which biological material is sampled from humans and health-related personal data is collected for research.
Clinical Studies - Jun 1, 2016 - Sep 14, 2022
Automatically Closed
Project leader: Semela David
Members: Stillhard Roman
Prevalence and functional role of read-through fusion transcripts in lung cancer
Jun 1, 2016The aim of this exploratory study is to assess the prevalence and the functional role of RTFTs in lung cancer. Total RNA extracted from lung biopsies obtained in 50 p...
Fundamental Research - Jun 1, 2016 - Dec 31, 2018
Automatically Closed
Project leader: Baty Florent
Members: Brutsche Martin
AdaptResponse
May 30, 2016The AdaptResponse study is a prospective, randomized, controlled, interventional, single-blinded, multi-center, post-market, global Cardiac Resynchronization Therapy (CRT) in heart failure (HF) clinical study. The purpose of this clinical study is...
Clinical Studies - May 30, 2016 - Dec 31, 2022
Completed
Project leader: Ammann Peter
Members: Vetsch Susanne
A Phase III Study of Pembrolizumab (MK-3475) vs. Chemotherapy in Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Stage IV Colorectal Carcinoma (KEYNOTE-177)
May 27, 2016Each subject will participate in the trial from the time the subject signs the Informed Consent Form (ICF) through the final contact. After a screening phase of up to 42 days, eligible subjects can be randomized to either pembrolizumab (experimental...
Clinical Studies - May 27, 2016 - Nov 30, 2020
Automatically Closed
Project leader: Weisshaupt Christian
SAKK 08/14 Investigation of Metformin in patients with castration resistant Prostate Cancer in combination with Enzalu-tamide vs. Enzalutamide alone (IMPROVE TRIAL)
May 20, 2016The current standard of care for patients with metastatic castration resistant prostate cancer (mCRPC) and dis-ease progression is either treatment with abiraterone acetate and prednisone in asymptomatic or mildly symp-tomatic patients without viscer...
Clinical Studies - May 20, 2016 - Jul 31, 2026
Ongoing
Project leader: Rothermundt Christian
VOYAGER PAD: An international, multicenter, randomized, double-blind, placebocontrolled
May 15, 2016
Clinical Studies - May 15, 2016 - Jan 15, 2019
Automatically Closed
Project leader: Dick Florian
Members: von Allmen Regula, Beutner Ulrich, Luethi Cornelia, Hechelhammer Lukas, Benecke Ulf, Poloczek Alexander
EFTR - Register
May 13, 2016Die endoskopische Vollwandresektion (endoscopic full thickness resection: EFTR) ist ein neuer therapeutischer und/oder diagnostischer Ansatz zur Behandlung von konventionell endoskopisch nicht angehbarer kolorektaler Neoplasien. Diese neue Technik...
Clinical Studies - May 13, 2016 - May 13, 2020
Completed
Project leader: Baumeler Stephan
BAY16277 RISE
May 13, 2016A Randomized, Double-Blind, Placebo-Controlled Phase II Study to Investigate the Efficacy and Safety of Riociguat in Patients With Diffuse Cutaneous Systemic Sclerosis (dcSSc) Evaluierung der Wirksamkeit und Sicherheit einer 52-wöchigen Behandlung m...
Clinical Studies - May 13, 2016 - Apr 28, 2019
Completed
Project leader: Müller Rüdiger
Members: Forrer Silvia, Bartz-Batliner Mira, Hutz Carina Liane, Schmidig Kathrin
A randomised controlled, international, multicentre crossover trial. We want to test, whether telehealthcare can improve HRQOL and reduce emergency admissions and hospitalisations due to AECOPD
May 11, 2016A randomised controlled, international, multicentre crossover trial. We want to test, whether telehealthcare can improve HRQOL and reduce emergency admissions and hospitalisations due to AECOPD.
Clinical Studies - May 11, 2016 - Dec 31, 2018
Automatically Closed
Project leader: Brutsche Martin
Members: Baty Florent, Rassouli Frank, Schlotter Sandra