Exploring the impact of hexagonal boron nitride (nanomedicines) on bacterial quorum sensing communication and its consequences on bacterial lung invasionand pathogenesis

Project

Exploring the impact of hexagonal boron nitride (nanomedicines) on bacterial quorum sensing communication and its consequences on bacterial lung invasionand pathogenesis

Automatically Closed · 2023 until 2024

Albrich Werner, Bürki-Turnherr Tina, Kahlert Christian, Nigg Susanne

Type

Fundamental Research

Units

Division of Infectious Diseases, Infection Prevention and Travel Medicine

Status

Automatically Closed

Start Date

2023

End Date

2024

Financing

KSSG

Partner

Empa: Dr. Tina Bürki, Group leader Particles@Barriers, Empa and Dr. Govind Gupta, scientist Particles@Barriers, Empa

Brief description/objective

In this interdisciplinary collaboration between Empa's Laboratory for Particles-Biology Interactions (Particles@Barriers subgroup) and the KSSG (Infektiologie/Spitalhygiene), we aim to study whether hexagonal boron nitride (hBN) could modulate host-invasion, virulence, and pathogenesis of Streptococcus pneumoniae by affecting luxP/luxS mediated quorum sensing signaling.