Projects
Search from 1082 projects:
1082 Project(s)
HIT-Studie
Feb 1, 2021Targeted correction of plasma sodium levels in hospitalized patients with hyponatremia: a randomized, controlled, parallel-group trial with blinded outcome assessment
Clinical Studies - Feb 1, 2021 - Dec 31, 2025
Ongoing
Project leader: Bilz Stefan
Members: Bontognali Martina, Räss Andrea, Rothlin Silvia, Grillmayr Victoria
I6T-MC-AMBI
Feb 1, 2021A Phase 3b, Randomized, Double-Blind, Parallel-Arm, Placebo- and Active- Controlled Treat-Through Study of Mirikizumab and Vedolizumab in participants with Moderately to Severely Active Ulcerative Colitis
Clinical Studies - Feb 1, 2021 - Jan 1, 2024
Completed
Project leader: Brand Stephan
Members: Smolders Jolijn, Krieger-Grübel Claudia
Development of the European Organisation for Research and Treatment of Cancer (EORTC)/ Cutaneous Lymphoma Task Force (CLTF) questionnaire to assess HRQoL in cutaneous lymphoma
Feb 1, 2021
Clinical Studies - Feb 1, 2021 - Aug 25, 2023
Automatically Closed
Project leader: Cozzio Antonio
RECOVER: Rheumatoid Covid-19 Vaccine Immune Response
Feb 1, 2021Untersuchung der Sicherheit und Effektivität von mRNA basierten COVID-19 Impfungen bei Patienten mit rheumatoider Arthritis - ein exploratives Forschungsprojekt
Clinical Studies - Feb 1, 2021 - Dec 31, 2022
Completed
Project leader: Rubbert-Roth Andrea
Members: Schmiedeberg Kristin, Bartz-Batliner Mira, Peischl Riana, Peischl Shirin, Sasselli Clelia, Hutz Carina Liane
I6T-MC-AMAP
Jan 29, 2021A Phase 3, Multicenter, Open-Label Extension Study to Evaluate the Long-Term Efficacy and Safety of Mirikizumab in Patients with Moderately to Severely Active Ulcerative Colitis LUCENT 3
Clinical Studies - Jan 29, 2021 - Dec 1, 2024
Ongoing
Project leader: Brand Stephan
Members: Krieger-Grübel Claudia, Smolders Jolijn
VitCov Studie
Jan 25, 2021High Dose Vitamin-D-substitution in Patients with COVID-19: a randomized, double blind, placebo controlled, multi-centre Study. The objective of the study is to test the hypothesis that patients with vitamin D deficiency suffering from COVID-19 trea...
Clinical Studies - Jan 25, 2021 - Dec 31, 2021
Automatically Closed
Project leader: Brändle Michael
Members: Bloch Nando, Räss Andrea
ESSENCE
Jan 1, 2021
Clinical Studies - Jan 1, 2021 - Dec 31, 2026
Ongoing
Project leader: Bilz Stefan
Eurythmy therapy versus slow movement fitness in the treatment of fatigue in metastatic breast cancer patients: the ERYT/CoordiFit randomized controlled trial
Jan 1, 2021Background: Cancer-related fatigue (CRF) is the most taxing symptom for many breast cancer patients during and after therapy. In patients with metastatic disease, the prevalence of CRF exceeds 75%. Currently, there is no gold standard for the treatme...
Clinical Studies - Jan 1, 2021 - Dec 31, 2024
Ongoing
Project leader: Schlaeppi Marc
Resistance Development in Escherichia coli at different pH following Delafloxacin and Ciprofloxacin Challenge
Jan 1, 2021Delafloxacin , a novel dual-targeting non-zwitterionic fluoroquinolone, has received approval by the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA) for the treatment of acute bacterial skin and skin structure infectio...
Fundamental Research - Jan 1, 2021 - Jan 1, 2023
Automatically Closed
Project leader: Babouee Flury Baharak
Translation of pre-treatment tumor kinetics and clinical and serological markers of the immune system in the treatment of advanced melanoma
Jan 1, 2021Bei diesem Projekt geht es um die Charakterisierung des Therapieansprechens von Melanommetastasen unter Systemtherapie mit anti-PD-1 Antikörpern, kombinierter Immuntherapie mit dem anti-PD-1 Antikörper Nivolumab und dem anti-CTLA-4 Antikörper Ipilimu...
Clinical Studies - Jan 1, 2021 - Dec 31, 2021
Completed
Project leader: Wagner Nikolaus
Decision-Making Analysis of next generation sequencing in glioblastoma in Switzerland
Jan 1, 2021Glioblastoma is the most frequent and most malignant primary brain tumour with an annual incidence of 3.2/100’000 1,2. The combination of histopathological features (nuclear atypia, mitosis, neoangiogenesis and/or necrosis) and molecular aberrations...
Clinical Studies - Jan 1, 2021 - Dec 1, 2021
Automatically Closed
Members: Putora Paul Martin
Towards identification of novel therapeutic targets: Assessment of proteasome-related alterations in MM patients’ datasets
Jan 1, 2021
Fundamental Research - Jan 1, 2021 - Dec 31, 2021
Automatically Closed
Project leader: Besse Lenka, Buljan Marija
Members: Besse Andrej
Clinical evaluation of a standard treatment algorithm for midshaft clavicle fractures
Jan 1, 2021The aim of this research project is to evaluate the evidence-based treatment standard for patients with midshaft clavicle fractures using an algorithmic approach in a Swiss multi-centre, prospective data collection. This algorithm includes not only t...
Register - Jan 1, 2021 - Dec 31, 2025
Ongoing
Project leader: Spross Christian
Members: Jost Bernhard, Zdravkovic Vilijam, Schöfl Thomas, Farei-Campagna Jan M
Diagnostic role of the "white test" with lipidic solution in the early intraoperative identification of open bile ducts for the prevention of bile leakage after liver resection - A randomized controlled multicentric superiority trial.
Jan 1, 2021Bile leakage (BL) is the most frequent complication after liver resection leading to the need of interventional drainage, ERCP or even reoperation. Strategies leading to a reduction of the rate of this complication are valuable. SMOFlipid 20% is a fa...
Clinical Studies - Jan 1, 2021 - Dec 31, 2023
Ongoing
Project leader: Tarantino Ignazio
Swiss Soliris® and Ultomiris® Reimbursement Registry SSURR: An observational registry for capturing data of patients suffering from paroxysmal nocturnal hemoglobinuria (PNH) who are treated with Soliris® (eculizumab) or Ultomiris® (ravulizumab)
Jan 1, 2021
Clinical Studies - Jan 1, 2021 - Dec 31, 2030
Ongoing
Project leader: Silzle Tobias
Members: Demmer-Steingruber Ruth, Frehner Jan
CATCH - Cascade genetic testing of familial hypercholesterolemia: the CATCH multicenter randomized controlled trial
Dec 15, 2020To test in a multicenter open-label randomized controlled trial across Switzerland whether a cascade screening programme for FH, in comparison with usual care, will increase the detection rate of FH within families. The primary outcome will be the d...
Clinical Studies - Dec 15, 2020 - Dec 30, 2023
Ongoing
Project leader: Rickli Hans
Members: Vetsch Susanne, Schneider Irene
SILENT 2
Dec 4, 2020Incidence of Silent Atrial Fibrillation in Patients With Clinically Silent Brain Ischemic Lesions Arterial Fibrillation (AF) is well-recognized as a cause for cryptogenic Acute Ischemic Stroke (AIS) and is associated with Silent Brain Infarction...
Clinical Studies - Dec 4, 2020 - Dec 4, 2024
Ongoing
Project leader: Ammann Peter, Kägi Georg
Members: Brenner Roman, Vetsch Susanne, Schneider Irene
Smartphone-Enabled Detection of COugh in COvid-19 (COCO): An Exploratory, Single-Center, Observational Cohort Study
Dec 3, 2020
Clinical Studies - Dec 3, 2020 - Dec 3, 2020
Automatically Closed
Project leader: Rassouli Frank
Members: Brutsche Martin, Tinschert Peter, Barata Filipe, Shih Iris
Validation of a textile-based monitoring device for the continuous surveillance of respiratory activity in patients during sedation
Dec 1, 2020
Clinical Studies - Dec 1, 2020 - Nov 30, 2021
Automatically Closed
ASSESS
Dec 1, 2020A randomized, double-blind, placebo-controlled, multi-Center Phase 2 study to assess the efficacy and safety of oral BAY 2327949 in patients with clinical diagnosis of chronic kidney disease due to diabetes or hypertension and at least one cardiovasc...
Clinical Studies - Dec 1, 2020 - Dec 31, 2021
Aborted
Project leader: Bilz Stefan
Members: Räss Andrea, Grillmayr Victoria