Tilman L B Hölting
Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma
Marchetto A, Dallmayer M, Romero-Pérez L, Hölting T, Amatruda J, Cossarizza A, Henssen A, Kirchner T, Moretti M, Cidre-Aranaz F, Sannino G, Musa J, Baldauf M, Gerke J, Ohmura S, Orth M, Knott M, Colombo M, Arrigoni C, Bardinet V, Saucier D, Wehweck F, Li J, Stein S, Grünewald T. Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma. Nat Commun 2020; 11:2423.
May 15, 2020Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma
May 15, 2020Nat Commun 2020; 11:2423
Marchetto Aruna, Dallmayer Marlene, Romero-Pérez Laura, Hölting Tilman L B, Amatruda James F, Cossarizza Andrea, Henssen Anton G, Kirchner Thomas, Moretti Matteo, Cidre-Aranaz Florencia, Sannino Giuseppina, Musa Julian, Baldauf Michaela, Gerke Julia S, Ohmura Shunya, Orth Martin F, Knott Maximilian M L, Colombo Maria V, Arrigoni Chiara, Bardinet Victor, Saucier David, Wehweck Fabienne S, Li Jing, Stein Stefanie, Grünewald Thomas G P
High Specificity of BCL11B and GLG1 for EWSR1-FLI1 and EWSR1-ERG Positive Ewing Sarcoma
Orth M, Li J, Marchetto A, Henssen A, Özen Ö, Sugita S, Hasegawa T, Kanaseki T, Bertram S, Dirksen U, Hartmann W, Kirchner T, Ohmura S, Gerke J, Cidre-Aranaz F, Hölting T, Dallmayer M, Wehweck F, Paul T, Musa J, Baldauf M, Surdez D, Delattre O, Knott M, Romero-Pérez L, Kasan M, Grünewald T. High Specificity of BCL11B and GLG1 for EWSR1-FLI1 and EWSR1-ERG Positive Ewing Sarcoma. Cancers (Basel) 2020; 12
Mar 10, 2020High Specificity of BCL11B and GLG1 for EWSR1-FLI1 and EWSR1-ERG Positive Ewing Sarcoma
Mar 10, 2020Cancers (Basel) 2020; 12
Orth Martin F, Li Jing, Marchetto Aruna, Henssen Anton G, Özen Özlem, Sugita Shintaro, Hasegawa Tadashi, Kanaseki Takayuki, Bertram Stefanie, Dirksen Uta, Hartmann Wolfgang, Kirchner Thomas, Ohmura Shunya, Gerke Julia S, Cidre-Aranaz Florencia, Hölting Tilman L B, Dallmayer Marlene, Wehweck Fabienne S, Paul Tanja, Musa Julian, Baldauf Michaela, Surdez Didier, Delattre Olivier, Knott Maximilian M L, Romero-Pérez Laura, Kasan Merve, Grünewald Thomas G P
Cooperation of cancer drivers with regulatory germline variants shapes clinical outcomes
Musa J, Stein S, Sannino G, Li J, Romero-Pérez L, Westermann F, Hartmann W, Dirksen U, Gymrek M, Anderson N, Shlien A, Rotblat B, Kirchner T, Delattre O, Baldauf M, Dallmayer M, Marchetto A, Cidre-Aranaz F, Aynaud M, Orth M, Knott M, Mirabeau O, Mazor G, Varon M, Hölting T, Grossetête S, Gartlgruber M, Surdez D, Gerke J, Ohmura S, Grünewald T. Cooperation of cancer drivers with regulatory germline variants shapes clinical outcomes. Nat Commun 2019; 10:4128.
Sep 11, 2019Cooperation of cancer drivers with regulatory germline variants shapes clinical outcomes
Sep 11, 2019Nat Commun 2019; 10:4128
Musa Julian, Stein Stefanie, Sannino Giuseppina, Li Jing, Romero-Pérez Laura, Westermann Frank, Hartmann Wolfgang, Dirksen Uta, Gymrek Melissa, Anderson Nathaniel D, Shlien Adam, Rotblat Barak, Kirchner Thomas, Delattre Olivier, Baldauf Michaela, Dallmayer Marlene, Marchetto Aruna, Cidre-Aranaz Florencia, Aynaud Marie-Ming, Orth Martin F, Knott Maximilian M L, Mirabeau Olivier, Mazor Gal, Varon Mor, Hölting Tilman L B, Grossetête Sandrine, Gartlgruber Moritz, Surdez Didier, Gerke Julia S, Ohmura Shunya, Grünewald Thomas G P
Targeting the CALCB/RAMP1 axis inhibits growth of Ewing sarcoma
Dallmayer M, Sannino G, Bach H, Kirchner T, Marchetto A, Orth M, Gerke J, Romero-Pérez L, Wehweck F, Cidre-Aranaz F, Stein S, Knott M, Musa J, Hölting T, Baldauf M, Alba Rubio R, Ohmura S, Li J, Grünewald T. Targeting the CALCB/RAMP1 axis inhibits growth of Ewing sarcoma. Cell Death Dis 2019; 10:116.
Feb 11, 2019Targeting the CALCB/RAMP1 axis inhibits growth of Ewing sarcoma
Feb 11, 2019Cell Death Dis 2019; 10:116
Dallmayer Marlene, Sannino Giuseppina, Bach Horacio, Kirchner Thomas, Marchetto Aruna, Orth Martin F, Gerke Julia S, Romero-Pérez Laura, Wehweck Fabienne S, Cidre-Aranaz Florencia, Stein Stefanie, Knott Max M L, Musa Julian, Hölting Tilman L B, Baldauf Michaela, Alba Rubio Rebeca, Ohmura Shunya, Li Jing, Grünewald Thomas G P
Functional genomics identifies AMPD2 as a new prognostic marker for undifferentiated pleomorphic sarcoma
Orth M, Sannino G, Knott M, Wehweck F, Ohmura S, Li J, Hakozaki M, Kirchner T, Dandekar T, Butt E, Marchetto A, Baldauf M, Dallmayer M, Gerke J, Knösel T, Altendorf-Hofmann A, Musa J, Alba-Rubio R, Stein S, Hölting T, Cidre-Aranaz F, Romero-Pérez L, Grünewald T. Functional genomics identifies AMPD2 as a new prognostic marker for undifferentiated pleomorphic sarcoma. Int J Cancer 2018; 144:859-867.
Dec 4, 2018Functional genomics identifies AMPD2 as a new prognostic marker for undifferentiated pleomorphic sarcoma
Dec 4, 2018Int J Cancer 2018; 144:859-867
Orth Martin F, Sannino Giuseppina, Knott Maximilian M L, Wehweck Fabienne, Ohmura Shunya, Li Jing, Hakozaki Michiyuki, Kirchner Thomas, Dandekar Thomas, Butt Elke, Marchetto Aruna, Baldauf Michaela, Dallmayer Marlene, Gerke Julia S, Knösel Thomas, Altendorf-Hofmann Annelore, Musa Julian, Alba-Rubio Rebeca, Stein Stefanie, Hölting Tilman L B, Cidre-Aranaz Florencia, Romero-Pérez Laura, Grünewald Thomas G P