Thomas Meyer
Safety, tolerability, and efficacy of fasudil in amyotrophic lateral sclerosis (ROCK-ALS): a phase 2, randomised, double-blind, placebo-controlled trial.
Koch J, Leha A, Bidner H, Cordts I, Dorst J, Günther R, Zeller D, Braun N, Metelmann M, Corcia P, Depla E, Weydt P, Meyer T, Grosskreutz J, Soriani M, Attarian S, Weishaupt J, Weyen U, Kuttler J, Zurek G, Rogers M, Feneberg E, Deschauer M, Neuwirth C, Wuu J, Ludolph A, Schmidt J, Remane Y, Camu W, Friede T, Benatar M, Weber M, Lingor P, ROCK-ALS Study group. Safety, tolerability, and efficacy of fasudil in amyotrophic lateral sclerosis (ROCK-ALS): a phase 2, randomised, double-blind, placebo-controlled trial. Lancet Neurol 2024; 23:1133-1146.
Nov 1, 2024Safety, tolerability, and efficacy of fasudil in amyotrophic lateral sclerosis (ROCK-ALS): a phase 2, randomised, double-blind, placebo-controlled trial.
Nov 1, 2024Lancet Neurol 2024; 23:1133-1146
Koch Jan Christoph, Leha Andreas, Bidner Helen, Cordts Isabell, Dorst Johannes, Günther René, Zeller Daniel, Braun Nathalie, Metelmann Moritz, Corcia Philippe, Depla Erik, Weydt Patrick, Meyer Thomas, Grosskreutz Julian, Soriani Marie-Hélène, Attarian Shahram, Weishaupt Jochen H, Weyen Ute, Kuttler Josua, Zurek Gabriela, Rogers Mary-Louise, Feneberg Emily, Deschauer Marcus, Neuwirth Christoph, Wuu Joanne, Ludolph Albert C., Schmidt Jens, Remane Yvonne, Camu William, Friede Tim, Benatar Michael, Weber Markus, Lingor Paul, ROCK-ALS Study group
Safety and efficacy of arimoclomol in patients with early amyotrophic lateral sclerosis (ORARIALS-01): a randomised, double-blind, placebo-controlled, multicentre, phase 3 trial.
Benatar M, Hansen T, Rom D, Geist M, Blaettler T, Camu W, Kuzma-Kozakiewicz M, van den Berg L, Juntas-Morales R, Chio A, Andersen P, Pradat P, Lange D, Van Damme P, Mora G, Grudniak M, Elliott M, Petri S, Olney N, Ladha S, Goyal N, Meyer T, Hanna M, Quinn C, Genge A, Zinman L, Jabari D, Shoesmith C, Ludolph A, Neuwirth C, Nations S, Shefner J, Turner M, Wuu J, Bennett R, Dang H, Sundgreen C, ORARIALS-01 trial team. Safety and efficacy of arimoclomol in patients with early amyotrophic lateral sclerosis (ORARIALS-01): a randomised, double-blind, placebo-controlled, multicentre, phase 3 trial. Lancet Neurol 2024; 23:687-699.
May 20, 2024Safety and efficacy of arimoclomol in patients with early amyotrophic lateral sclerosis (ORARIALS-01): a randomised, double-blind, placebo-controlled, multicentre, phase 3 trial.
May 20, 2024Lancet Neurol 2024; 23:687-699
Benatar Michael, Hansen Thomas, Rom Dror, Geist Marie A, Blaettler Thomas, Camu William, Kuzma-Kozakiewicz Magdalena, van den Berg Leonard H, Juntas-Morales Raul, Chio Adriano, Andersen Peter Munch, Pradat Pierre-Francois, Lange Dale J, Van Damme Philip, Mora Gabriele, Grudniak Mariusz, Elliott Matthew, Petri Susanne, Olney Nicholas, Ladha Shafeeq S, Goyal Namita A, Meyer Thomas, Hanna Michael G, Quinn Colin, Genge Angela, Zinman Lorne, Jabari Duaa, Shoesmith Christen, Ludolph Albert C., Neuwirth Christoph, Nations Sharon, Shefner Jeremy M, Turner Martin R, Wuu Joanne, Bennett Richard, Dang Hoang, Sundgreen Claus, ORARIALS-01 trial team
Author Correction: Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology.
van Rheenen W, van der Spek R, Bakker M, Van Vugt J, Hop P, Zwamborn R, de Klein N, Westra H, Bakker O, Deelen P, Shireby G, Hannon E, Moisse M, Baird D, Restuadi R, Dolzhenko E, Dekker A, Gawor K, Westeneng H, Tazelaar G, van Eijk K, Kooyman M, Byrne R, Doherty M, Heverin M, Al Khleifat A, Iacoangeli A, Shatunov A, Ticozzi N, Cooper-Knock J, Smith B, Gromicho M, Chandran S, Pal S, Morrison K, Shaw P, Hardy J, Orrell R, Sendtner M, Meyer T, Başak N, van der Kooi A, Ratti A, Fogh I, Gellera C, Lauria G, Corti S, Cereda C, Sproviero D, D'Alfonso S, Sorarù G, Siciliano G, Filosto M, Padovani A, Chio A, Calvo A, Moglia C, Brunetti M, Canosa A, Grassano M, Beghi E, Pupillo E, Logroscino G, Nefussy B, Osmanovic A, Nordin A, Lerner Y, Zabari M, Gotkine M, Baloh R, Bell S, Vourc'h P, Corcia P, Couratier P, Millecamps S, Meininger V, Salachas F, Mora Pardina J, Assialioui A, Rojas-García R, Dion P, Ross J, Ludolph A, Weishaupt J, Brenner D, Freischmidt A, Bensimon G, Brice A, Dürr A, Payan C, Saker-Delye S, Wood N, Topp S, Rademakers R, Tittmann L, Lieb W, Franke A, Ripke S, Braun A, Kraft J, Whiteman D, Olsen C, Uitterlinden A, Hofman A, Rietschel M, Cichon S, Nöthen M, Amouyel P, SLALOM Consortium, PARALS Consortium, SLAGEN Consortium, SLAP Consortium, Traynor B, Singleton A, Mitne Neto M, Cauchi R, Ophoff R, Wiedau-Pazos M, Lomen-Hoerth C, Van Deerlin V, Grosskreutz J, Roediger A, Gaur N, Jörk A, Barthel T, Theele E, Ilse B, Stubendorff B, Witte O, Steinbach R, Hübner C, Graff C, Brylev L, Fominykh V, Demeshonok V, Ataulina A, Rogelj B, Koritnik B, Zidar J, Ravnik-Glavač M, Glavač D, Stević Z, Drory V, Povedano M, Blair I, Kiernan M, Benyamin B, Henderson R, Furlong S, Mathers S, McCombe P, Needham M, Ngo S, Nicholson G, Pamphlett R, Rowe D, Steyn F, Williams K, Mather K, Sachdev P, Henders A, Wallace L, de Carvalho M, Pinto S, Petri S, Weber M, Rouleau G, Silani V, Curtis C, Breen G, Glass J, Brown R, Landers J, Shaw C, Andersen P, Groen E, van Es M, Pasterkamp R, Fan D, Garton F, McRae A, Davey Smith G, Gaunt T, Eberle M, Mill J, McLaughlin R, Hardiman O, Kenna K, Wray N, Tsai E, Runz H, Franke L, Al-Chalabi A, Van Damme P, van den Berg L, Veldink J. Author Correction: Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology. Nat Genet 2022; 54:361.
Mar 1, 2022Author Correction: Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology.
Mar 1, 2022Nat Genet 2022; 54:361
van Rheenen Wouter, van der Spek Rick A A, Bakker Mark K, Van Vugt Joke J F A, Hop Paul J, Zwamborn Ramona A J, de Klein Niek, Westra Harm-Jan, Bakker Olivier B, Deelen Patrick, Shireby Gemma, Hannon Eilis, Moisse Matthieu, Baird Denis, Restuadi Restuadi, Dolzhenko Egor, Dekker Annelot M, Gawor Klara, Westeneng Henk-Jan, Tazelaar Gijs H P, van Eijk Kristel R, Kooyman Maarten, Byrne Ross P, Doherty Mark, Heverin Mark, Al Khleifat Ahmad, Iacoangeli Alfredo, Shatunov Aleksey, Ticozzi Nicola, Cooper-Knock Johnathan, Smith Bradley N, Gromicho Marta, Chandran Siddharthan, Pal Suvankar, Morrison Karen E, Shaw Pamela J, Hardy John, Orrell Richard W, Sendtner Michael, Meyer Thomas, Başak Nazli, van der Kooi Anneke J, Ratti Antonia, Fogh Isabella, Gellera Cinzia, Lauria Giuseppe, Corti Stefania, Cereda Cristina, Sproviero Daisy, D'Alfonso Sandra, Sorarù Gianni, Siciliano Gabriele, Filosto Massimiliano, Padovani Alessandro, Chio Adriano, Calvo Andrea, Moglia Cristina, Brunetti Maura, Canosa Antonio, Grassano Maurizio, Beghi Ettore, Pupillo Elisabetta, Logroscino Giancarlo, Nefussy Beatrice, Osmanovic Alma, Nordin Angelica, Lerner Yossef, Zabari Michal, Gotkine Marc, Baloh Robert H, Bell Shaughn, Vourc'h Patrick, Corcia Philippe, Couratier Philippe, Millecamps Stéphanie, Meininger Vincent, Salachas François, Mora Pardina Jesus S, Assialioui Abdelilah, Rojas-García Ricardo, Dion Patrick A, Ross Jay P, Ludolph Albert C, Weishaupt Jochen H, Brenner David, Freischmidt Axel, Bensimon Gilbert, Brice Alexis, Dürr Alexandra, Payan Christine A M, Saker-Delye Safa, Wood Nicholas W, Topp Simon, Rademakers Rosa, Tittmann Lukas, Lieb Wolfgang, Franke Andre, Ripke Stephan, Braun Alice, Kraft Julia, Whiteman David C, Olsen Catherine M, Uitterlinden André G, Hofman Albert, Rietschel Marcella, Cichon Sven, Nöthen Markus M, Amouyel Philippe, SLALOM Consortium, PARALS Consortium, SLAGEN Consortium, SLAP Consortium, Traynor Bryan J, Singleton Andrew B, Mitne Neto Miguel, Cauchi Ruben J, Ophoff Roel A, Wiedau-Pazos Martina, Lomen-Hoerth Catherine, Van Deerlin Vivianna M, Grosskreutz Julian, Roediger Annekathrin, Gaur Nayana, Jörk Alexander, Barthel Tabea, Theele Erik, Ilse Benjamin, Stubendorff Beatrice, Witte Otto W, Steinbach Robert, Hübner Christian A, Graff Caroline, Brylev Lev, Fominykh Vera, Demeshonok Vera, Ataulina Anastasia, Rogelj Boris, Koritnik Blaž, Zidar Janez, Ravnik-Glavač Metka, Glavač Damjan, Stević Zorica, Drory Vivian, Povedano Monica, Blair Ian P, Kiernan Matthew C, Benyamin Beben, Henderson Robert D, Furlong Sarah, Mathers Susan, McCombe Pamela A, Needham Merrilee, Ngo Shyuan T, Nicholson Garth A, Pamphlett Roger, Rowe Dominic B, Steyn Frederik J, Williams Kelly L, Mather Karen A, Sachdev Perminder S, Henders Anjali K, Wallace Leanne, de Carvalho Mamede, Pinto Susana, Petri Susanne, Weber Markus, Rouleau Guy A, Silani Vincenzo, Curtis Charles J, Breen Gerome, Glass Jonathan D, Brown Robert H, Landers John E, Shaw Christopher E, Andersen Peter M, Groen Ewout J N, van Es Michael A, Pasterkamp R Jeroen, Fan Dongsheng, Garton Fleur C, McRae Allan F, Davey Smith George, Gaunt Tom R, Eberle Michael A, Mill Jonathan, McLaughlin Russell L, Hardiman Orla, Kenna Kevin P, Wray Naomi R, Tsai Ellen, Runz Heiko, Franke Lude, Al-Chalabi Ammar, Van Damme Philip, van den Berg Leonard H, Veldink Jan H
Clinical trials in pediatric ALS: a TRICALS feasibility study.
Kliest T, van Eijk R, Al-Chalabi A, Albanese A, Andersen P, Amador M, BrÅthen G, Brunaud-Danel V, Brylev L, Camu W, de Carvalho M, Cereda C, Cetin H, Chaverri D, Chio A, Corcia P, Couratier P, De Marchi F, Desnuelle C, van Es M, Esteban J, Filosto M, GarcÍa Redondo A, Grosskreutz J, Hanemann C, Holmøy T, HØyer H, Ingre C, Koritnik B, Kuzma-Kozakiewicz M, Lambert T, Leigh P, Lunetta C, Mandrioli J, McDermott C, Meyer T, Mora J, Petri S, Povedano M, Reviers E, Riva N, Roes K, Rubio M, Salachas F, Sarafov S, Sorarù G, Stević Z, Svenstrup K, MØller A, Turner M, Van Damme P, Van Leeuwen L, Varona L, VÁzquez Costa J, Weber M, Hardiman O, van den Berg L. Clinical trials in pediatric ALS: a TRICALS feasibility study. Amyotroph Lateral Scler Frontotemporal Degener 2022; 23:481-488.
Feb 16, 2022Clinical trials in pediatric ALS: a TRICALS feasibility study.
Feb 16, 2022Amyotroph Lateral Scler Frontotemporal Degener 2022; 23:481-488
Kliest Tessa, van Eijk Ruben P A, Al-Chalabi Ammar, Albanese Alberto, Andersen Peter M, Amador Maria Del Mar, BrÅthen Geir, Brunaud-Danel Veronique, Brylev Lev, Camu William, de Carvalho Mamede, Cereda Cristina, Cetin Hakan, Chaverri Delia, Chio Adriano, Corcia Philippe, Couratier Philippe, De Marchi Fabiola, Desnuelle Claude, van Es Michael A, Esteban JesÚs, Filosto Massimiliano, GarcÍa Redondo Alberto, Grosskreutz Julian, Hanemann Clemens O, Holmøy Trygve, HØyer Helle, Ingre Caroline, Koritnik Blaž, Kuzma-Kozakiewicz Magdalena, Lambert Thomas, Leigh Peter N, Lunetta Christian, Mandrioli Jessica, McDermott Christopher J, Meyer Thomas, Mora Jesus S, Petri Susanne, Povedano Monica, Reviers Evy, Riva Nilo, Roes Kit C B, Rubio Miguel Á, Salachas François, Sarafov Stayko, Sorarù Gianni, Stević Zorica, Svenstrup Kirsten, MØller Anette Torvin, Turner Martin R, Van Damme Philip, Van Leeuwen Lucie A G, Varona Luis, VÁzquez Costa Juan F, Weber Markus, Hardiman Orla, van den Berg Leonard H
Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology.
van Rheenen W, van der Spek R, Bakker M, Farei-Campagna J, Hop P, Zwamborn R, de Klein N, Westra H, Bakker O, Deelen P, Shireby G, Hannon E, Moisse M, Baird D, Restuadi R, Dolzhenko E, Dekker A, Gawor K, Westeneng H, Tazelaar G, van Eijk K, Kooyman M, Byrne R, Doherty M, Heverin M, Al Khleifat A, Iacoangeli A, Shatunov A, Ticozzi N, Cooper-Knock J, Smith B, Gromicho M, Chandran S, Pal S, Morrison K, Openshaw P, Hardy J, Orrell R, Sendtner M, Meyer T, Başak N, van der Kooi A, Ratti A, Fogh I, Gellera C, Lauria G, Corti S, Cereda C, Sproviero D, D'Alfonso S, Sorarù G, Siciliano G, Filosto M, Padovani A, Chio A, Calvo A, Moglia C, Brunetti M, Canosa A, Grassano M, Beghi E, Pupillo E, Logroscino G, Nefussy B, Osmanovic A, Nordin A, Lerner Y, Zabari M, Gotkine M, Baloh R, Bell S, Vourc'h P, Corcia P, Couratier P, Millecamps S, Meininger V, Salachas F, Mora J, Assialioui A, Rojas-García R, Dion P, Ross J, Ludolph A, Weishaupt J, Brenner D, Freischmidt A, Bensimon G, Brice A, Dürr A, Payan C, Saker-Delye S, Wood N, Topp S, Rademakers R, Tittmann L, Lieb W, Klein-Franke A, Ripke S, Braun A, Kraft J, Whiteman D, Olsen C, Uitterlinden A, Hofman A, Rietschel M, Cichon S, Nöthen M, Amouyel P, SLALOM Consortium, PARALS Consortium, SLAGEN Consortium, SLAP Consortium, Traynor B, Singleton A, Mitne Neto M, Cauchi R, Ophoff R, Wiedau-Pazos M, Lomen-Hoerth C, Van Deerlin V, Grosskreutz J, Roediger A, Gaur N, Jörk A, Barthel T, Theele E, Ilse B, Stubendorff B, Witte O, Steinbach R, Hübner C, Graff C, Brylev L, Fominykh V, Demeshonok V, Ataulina A, Rogelj B, Koritnik B, Zidar J, Ravnik-Glavač M, Glavač D, Stević Z, Drory V, Povedano M, Blair I, Kiernan M, Benyamin B, Henderson R, Furlong S, Mathers S, McCombe P, Needham M, Ngo S, Nicholson G, Pamphlett R, Rowe D, Steyn F, Williams K, Mather K, Sachdev P, Henders A, Wallace L, de Carvalho M, Pinto S, Petri S, Weber M, Rouleau G, Silani V, Curtis C, Breen G, Glass J, Brown R, Landers J, Shaw C, Andersen P, Groen E, van Es M, Pasterkamp R, Fan D, Garton F, McRae A, Davey Smith G, Gaunt T, Eberle M, Mill J, McLaughlin R, Hardiman O, Kenna K, Wray N, Tsai E, Runz H, Franke L, Al-Chalabi A, Van Damme P, van den Berg L, Veldink J. Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology. Nat Genet 2021; 53:1636-1648.
Dec 6, 2021Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology.
Dec 6, 2021Nat Genet 2021; 53:1636-1648
van Rheenen Wouter, van der Spek Rick A A, Bakker Mark K, Farei-Campagna Jan Marino, Hop Paul J, Zwamborn Ramona A J, de Klein Niek, Westra Harm-Jan, Bakker Olivier B, Deelen Patrick, Shireby Gemma, Hannon Eilis, Moisse Matthieu, Baird Denis, Restuadi Restuadi, Dolzhenko Egor, Dekker Annelot M, Gawor Klara, Westeneng Henk-Jan, Tazelaar Gijs H P, van Eijk Kristel R, Kooyman Maarten, Byrne Ross P, Doherty Mark, Heverin Mark, Al Khleifat Ahmad, Iacoangeli Alfredo, Shatunov Aleksey, Ticozzi Nicola, Cooper-Knock Johnathan, Smith Bradley N, Gromicho Marta, Chandran Siddharthan, Pal Suvankar, Morrison Karen E, Openshaw Peter J M, Hardy John, Orrell Richard W, Sendtner Michael, Meyer Thomas, Başak Nazli A, van der Kooi Anneke J, Ratti Antonia, Fogh Isabella, Gellera Cinzia, Lauria Giuseppe, Corti Stefania, Cereda Cristina, Sproviero Daisy, D'Alfonso Sandra, Sorarù Gianni, Siciliano Gabriele, Filosto Massimiliano, Padovani Alessandro, Chio Adriano, Calvo Andrea, Moglia Cristina, Brunetti Maura, Canosa Antonio, Grassano Maurizio, Beghi Ettore, Pupillo Elisabetta, Logroscino Giancarlo, Nefussy Beatrice, Osmanovic Alma, Nordin Angelica, Lerner Yossef, Zabari Michal, Gotkine Marc, Baloh Robert H, Bell Shaughn, Vourc'h Patrick, Corcia Philippe, Couratier Philippe, Millecamps Stéphanie, Meininger Vincent, Salachas François, Mora Jesus S, Assialioui Abdelilah, Rojas-García Ricardo, Dion Patrick A, Ross Jay P, Ludolph Albert C., Weishaupt Jochen H, Brenner David, Freischmidt Axel, Bensimon Gilbert, Brice Alexis, Dürr Alexandra, Payan Christine A M, Saker-Delye Safaa, Wood Nicholas W, Topp Simon, Rademakers Rosa, Tittmann Lukas, Lieb Wolfgang, Klein-Franke Andreas, Ripke Stephan, Braun Alice, Kraft Julia, Whiteman David C, Olsen Catherine M, Uitterlinden André G, Hofman Albert, Rietschel Marcella, Cichon Sven, Nöthen Markus M, Amouyel Philippe, SLALOM Consortium, PARALS Consortium, SLAGEN Consortium, SLAP Consortium, Traynor Bryan J, Singleton Andrew B, Mitne Neto Miguel, Cauchi Ruben J, Ophoff Roel A, Wiedau-Pazos Martina, Lomen-Hoerth Catherine, Van Deerlin Vivianna M, Grosskreutz Julian, Roediger Annekathrin, Gaur Nayana, Jörk Alexander, Barthel Tabea, Theele Erik, Ilse Benjamin, Stubendorff Beatrice, Witte Otto W, Steinbach Robert, Hübner Christian A, Graff Caroline, Brylev Lev, Fominykh Vera, Demeshonok Vera, Ataulina Anastasia, Rogelj Boris, Koritnik Blaž, Zidar Janez, Ravnik-Glavač Metka, Glavač Damjan, Stević Zorica, Drory Vivian E, Povedano Monica, Blair Ian P, Kiernan Matthew C, Benyamin Beben, Henderson Robert D, Furlong Sarah, Mathers Susan, McCombe Pamela A, Needham Merrilee, Ngo Shyuan T, Nicholson Garth A, Pamphlett Roger, Rowe Dominic B, Steyn Frederik J, Williams Kelly L, Mather Karen A, Sachdev Perminder S, Henders Anjali K, Wallace Leanne, de Carvalho Mamede, Pinto Susana, Petri Susanne, Weber Markus, Rouleau Guy A, Silani Vincenzo, Curtis Charles J, Breen Gerome, Glass Jonathan D, Brown Robert H, Landers John E, Shaw Christopher E, Andersen Peter Munch, Groen Ewout J N, van Es Michael A, Pasterkamp R Jeroen, Fan Dongsheng, Garton Fleur C, McRae Allan F, Davey Smith George, Gaunt Tom R, Eberle Michael A, Mill Jonathan, McLaughlin Russell L, Hardiman Orla, Kenna Kevin P, Wray Naomi R, Tsai Ellen, Runz Heiko, Franke Lude, Al-Chalabi Ammar, Van Damme Philip, van den Berg Leonard H, Veldink Jan H
Challenges and opportunities for Multi-National Investigator-Initiated clinical trials for ALS: European and United States collaborations
Lingor P, Tostmann R, Neuwirth C, Meyer T, Lengenfeld T, Leha A, Kuttler J, Kollewe K, Kassubek J, Ilse B, Günther R, Ahmed R, Langbein T, Wuu J, Hennecke C, Hussain S, Statland J, Koch J, Benatar M. Challenges and opportunities for Multi-National Investigator-Initiated clinical trials for ALS: European and United States collaborations. Amyotroph Lateral Scler Frontotemporal Degener 2021; 22:419-425.
Feb 3, 2021Challenges and opportunities for Multi-National Investigator-Initiated clinical trials for ALS: European and United States collaborations
Feb 3, 2021Amyotroph Lateral Scler Frontotemporal Degener 2021; 22:419-425
Lingor Paul, Tostmann Ralf, Neuwirth Christoph, Meyer Thomas, Lengenfeld Teresa, Leha Andreas, Kuttler Josua, Kollewe Katja, Kassubek Jan, Ilse Benjamin, Günther René, Ahmed Raees, Langbein Thomas, Wuu Joanne, Hennecke Christiane, Hussain Sumaira, Statland Jeffrey M, Koch Jan C, Benatar Michael
Reply: Adult-onset distal spinal muscular atrophy: a new phenotype associated with KIF5A mutations
German ALS network MND-NET, Weis J, Dorst J, Volk A, Borck G, Sperfeld A, de Carvalho M, Klopstock T, Sendtner M, Otto M, Schuster J, Weishaupt J, Andersen P, Ludolph A, Meitinger T, Freischmidt A, Danzer K, Braak H, Del Tredici K, Jablonka S, Kubisch C, Zeller D, Weydt P, Grosskreutz J, Meyer T, Petri S, Grehl T, Müller K, Yilmaz R, Rosenbohm A, Ruf W, Neuwirth C, Hübers A, Günther K, Knehr A, Jordan B, Schrank B, Claeys K, Pinto S, Weber M, Brenner D. Reply: Adult-onset distal spinal muscular atrophy: a new phenotype associated with KIF5A mutations. Brain 2019; 142:e67.
Jan 1, 2019Reply: Adult-onset distal spinal muscular atrophy: a new phenotype associated with KIF5A mutations
Jan 1, 2019Brain 2019; 142:e67
German ALS network MND-NET, Weis Joachim, Dorst Johannes, Volk Alexander E, Borck Guntram, Sperfeld Anne, de Carvalho Mamede, Klopstock Thomas, Sendtner Michael, Otto Markus, Schuster Joachim, Weishaupt Jochen H, Andersen Peter M, Ludolph Albert C, Meitinger Thomas, Freischmidt Axel, Danzer Karin M, Braak Heiko, Del Tredici Kelly, Jablonka Sibylle, Kubisch Christian, Zeller Daniel, Weydt Patrick, Grosskreutz Julian, Meyer Thomas, Petri Susanne, Grehl Torsten, Müller Kathrin, Yilmaz Rüstem, Rosenbohm Angela, Ruf Wolfgang, Neuwirth Christoph, Hübers Annemarie, Günther Kornelia, Knehr Antje, Jordan Berit, Schrank Berthold, Claeys Kristl G, Pinto Susana, Weber Markus, Brenner David
Hot-spot KIF5A mutations cause familial ALS
Weishaupt J, Weis J, Dorst J, Volk A, Borck G, Sperfeld A, de Carvalho M, Klopstock T, Sendtner M, Otto M, Schuster J, Andersen P, Ludolph A, Strom T, Meitinger T, Freischmidt A, Danzer K, Braak H, Del Tredici K, Jablonka S, Kubisch C, German ALS network MND-NET, Ruf W, Weydt P, Grosskreutz J, Meyer T, Petri S, Grehl T, Müller K, Yilmaz R, Neuwirth C, Weber M, Zeller D, Hübers A, Günther K, Knehr A, Jordan B, Schrank B, Claeys K, Pinto S, Brenner D. Hot-spot KIF5A mutations cause familial ALS. Brain 2018
Jan 12, 2018Hot-spot KIF5A mutations cause familial ALS
Jan 12, 2018Brain 2018
Weishaupt Jochen H, Weis Joachim, Dorst Johannes, Volk Alexander E, Borck Guntram, Sperfeld Anne, de Carvalho Mamede, Klopstock Thomas, Sendtner Michael, Otto Markus, Schuster Joachim, Andersen Peter M, Ludolph Albert C, Strom Tim M, Meitinger Thomas, Freischmidt Axel, Danzer Karin M, Braak Heiko, Del Tredici Kelly, Jablonka Sibylle, Kubisch Christian, German ALS network MND-NET, Ruf Wolfgang, Weydt Patrick, Grosskreutz Julian, Meyer Thomas, Petri Susanne, Grehl Torsten, Müller Kathrin, Yilmaz Rüstem, Neuwirth Christoph, Weber Markus, Zeller Daniel, Hübers Annemarie, Günther Kornelia, Knehr Antje, Jordan Berit, Schrank Berthold, Claeys Kristl G, Pinto Susana, Brenner David
July 2017 ENCALS statement on edaravone
van den Berg L, Silani V, Shaw P, Salachas F, Povedano Panades M, Petri S, Nygren I, Mora Pardina J, Mitre Ropero B, Staaf G, Svenstrup K, Hardiman O, Wolf J, Weydt P, Weber M, van der Kooi A, Van Damme P, Tysnes O, Talbot K, Meyer T, McDermott C, Ludolph A, Desnuelle C, de Carvalho M, Danielsson O, Couratier P, Corcia P, Chio A, Chandran S, Andersen P, Grehl T, Grosskreutz J, Laaksovirta H, KuzmaKozakiewicz M, Koritnik B, Koch J, Kleveland G, Karlsborg M, Ingre C, Holmøy T, Al-Chalabi A. July 2017 ENCALS statement on edaravone. Amyotroph Lateral Scler Frontotemporal Degener 2017; 18:471-474.
Oct 4, 2017July 2017 ENCALS statement on edaravone
Oct 4, 2017Amyotroph Lateral Scler Frontotemporal Degener 2017; 18:471-474
van den Berg Leonard H, Silani Vincenzo, Shaw Pamela, Salachas François, Povedano Panades Mónica, Petri Susanne, Nygren Ingela, Mora Pardina Jesus, Mitre Ropero Bernardo, Staaf Gert, Svenstrup Kirsten, Hardiman Orla, Wolf Joachim, Weydt Patrick, Weber Markus, van der Kooi Anneke, Van Damme Philip, Tysnes Ole-Bjørn, Talbot Kevin, Meyer Thomas, McDermott Christopher, Ludolph Albert, Desnuelle Claude, de Carvalho Mamede, Danielsson Olof, Couratier Philippe, Corcia Philippe, Chio Adriano, Chandran Siddharthan, Andersen Peter M, Grehl Torsten, Grosskreutz Julian, Laaksovirta Hannu, KuzmaKozakiewicz Magdalena, Koritnik Blaž, Koch Jan Christoph, Kleveland Grethe, Karlsborg Merete, Ingre Caroline, Holmøy Trygve, Al-Chalabi Ammar
Sequence variations in C9orf72 downstream of the hexanucleotide repeat region and its effect on repeat-primed PCR interpretation: a large multinational screening study
Nordin A, Burkhardt C, Neuwirth C, Holmøy T, Morita M, Tysnes O, Benatar M, Wuu J, Lange D, Bisgård C, Asgari N, Tarvainen I, Brännström T, Weber M, Schweikert K, Grehl T, Akimoto C, Wuolikainen A, Alstermark H, Forsberg K, Baumann P, Pinto S, de Carvalho M, Hübers A, Nordin F, Ludolph A, Weishaupt J, Meyer T, Andersen P. Sequence variations in C9orf72 downstream of the hexanucleotide repeat region and its effect on repeat-primed PCR interpretation: a large multinational screening study. Amyotroph Lateral Scler Frontotemporal Degener 2016; 18:256-264.
Dec 12, 2016Sequence variations in C9orf72 downstream of the hexanucleotide repeat region and its effect on repeat-primed PCR interpretation: a large multinational screening study
Dec 12, 2016Amyotroph Lateral Scler Frontotemporal Degener 2016; 18:256-264
Nordin Angelica, Burkhardt Christian, Neuwirth Christoph, Holmøy Trygve, Morita Mitsuya, Tysnes Ole-Bjørn, Benatar Michael, Wuu Joanne, Lange Dale J, Bisgård Carsten, Asgari Nasrin, Tarvainen Ilkka, Brännström Thomas, Weber Markus, Schweikert Kathi, Grehl Torsten, Akimoto Chizuru, Wuolikainen Anna, Alstermark Helena, Forsberg Karin, Baumann Peter, Pinto Susana, de Carvalho Mamede, Hübers Annemarie, Nordin Frida, Ludolph Albert C, Weishaupt Jochen H, Meyer Thomas, Andersen Peter M
Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis
Zhang K, Arcuti S, Brunetti M, Moglia C, Calvo A, Ratti A, Tiloca C, Gellera C, Pensato V, Mazzini L, Capozzo R, Zecca C, Blair I, Stuit R, Muller B, Filosto M, Padovani A, Riva N, Penco S, Lunetta C, Sorarù G, Bertolin C, Blauw H, Curtis C, Hofman A, Estrada K, Rivadeneira F, Uitterlinden A, Dartigues J, Tzourio C, Amouyel P, van der Kooi A, de Visser M, D'Alfonso S, Comi G, Del Bo R, Cereda C, Pansarasa O, Smith B, Shaw C, Weber M, Goris A, Nöthen M, McCann E, Veldink J, Corcia P, Andersen P, Hardiman O, Landers J, Glass J, Brown R, Pers T, Franke L, Van Damme P, Vourc'h P, Silani V, van den Berg L, Al-Chalabi A, Breen G, Lewis C, Pasterkamp R, van Es M, de Bakker P, Visscher P, Wray N, Robberecht W, Weishaupt J, Stubendorff B, Prell T, Ringer T, Witte O, Grosskreutz J, Kiernan M, Pamphlett R, Rowe D, Nicholson G, Kurth I, Hübner C, Ludolph A, Powell J, Logroscino G, Tortelli R, Pupillo E, Beghi E, Chio A, Casale F, Leigh P, Fifita J, Chandran S, Koritnik B, Ravnik-Glavač M, Vrabec K, Rogelj B, Lin K, Ticozzi N, Vajda A, Menelaou A, Medic J, Zidar J, Leonardis L, Polak M, Rojas-García R, Mora J, Pinto S, de Carvalho M, Meininger V, Salachas F, Millecamps S, Grošelj L, Brands W, Schellevis R, Robinson M, de Jong S, Võsa U, van der Spek R, Pulit S, Diekstra F, McLaughlin R, Dekker A, Shatunov A, Yang J, Fogh I, Harschnitz O, van Eijk K, Kenna K, Jones A, Sproviero W, Blokhuis A, Koppers M, Tazelaar G, van Doormaal P, van Rheenen W, Colville S, Cichon S, Maurel C, Andres C, Radivojkov-Blagojevic M, Lichtner P, Meitinger T, Parman Y, Hamzeiy H, Tunca C, Basak A, Bensimon G, Landwehrmeyer B, Rietschel M, Franke A, Lieb W, Tittmann L, Wood N, Dürr A, Saker-Delye S, Payan C, Brice A, McCluskey L, Elman L, Topp S, Malaspina A, Fratta P, Sidle K, Pittman A, Orrell R, Hardy J, Shaw P, Morrison K, Petri S, Abdulla S, Trojanowski J, Van Deerlin V, Lomen-Hoerth C, Wiedau-Pazos M, Staats K, Ophoff R, Meyer T, Sendtner M, Drepper C, Swingler R. Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis. Nat Genet 2016; 48:1043-8.
Jul 25, 2016Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis
Jul 25, 2016Nat Genet 2016; 48:1043-8
Zhang Katharine, Arcuti Simona, Brunetti Maura, Moglia Cristina, Calvo Andrea, Ratti Antonia, Tiloca Cinzia, Gellera Cinzia, Pensato Viviana, Mazzini Letizia, Capozzo Rosa, Zecca Chiara, Blair Ian, Stuit Robbert Jan, Muller Bernard, Filosto Massimiliano, Padovani Alessandro, Riva Nilo, Penco Silvana, Lunetta Christian, Sorarù Gianni, Bertolin Cinzia, Blauw Hylke M, Curtis Charles, Hofman Albert, Estrada Karol, Rivadeneira Fernando, Uitterlinden André G, Dartigues Jean-François, Tzourio Christophe, Amouyel Philippe, van der Kooi Anneke J, de Visser Marianne, D'Alfonso Sandra, Comi Giacomo P, Del Bo Roberto, Cereda Cristina, Pansarasa Orietta, Smith Bradley N, Shaw Christopher E, Weber Markus, Goris An, Nöthen Markus M, McCann Emily P, Veldink Jan H, Corcia Philippe, Andersen Peter M, Hardiman Orla, Landers John E, Glass Jonathan D, Brown Robert H, Pers Tune H, Franke Lude, Van Damme Philip, Vourc'h Patrick, Silani Vincenzo, van den Berg Leonard H, Al-Chalabi Ammar, Breen Gerome, Lewis Cathryn M, Pasterkamp R Jeroen, van Es Michael A, de Bakker Paul I W, Visscher Peter M, Wray Naomi R, Robberecht Wim, Weishaupt Jochen H, Stubendorff Beatrice, Prell Tino, Ringer Thomas, Witte Otto W, Grosskreutz Julian, Kiernan Matthew C, Pamphlett Roger, Rowe Dominic B, Nicholson Garth A, Kurth Ingo, Hübner Christian A, Ludolph Albert C, Powell John, Logroscino Giancarlo, Tortelli Rosanna, Pupillo Elisabetta, Beghi Ettore, Chio Adriano, Casale Federico, Leigh P Nigel, Fifita Jennifer A, Chandran Siddharthan, Koritnik Blaž, Ravnik-Glavač Metka, Vrabec Katarina, Rogelj Boris, Lin Kuang, Ticozzi Nicola, Vajda Alice, Menelaou Androniki, Medic Jelena, Zidar Janez, Leonardis Lea, Polak Meraida, Rojas-García Ricardo, Mora Jesus S, Pinto Susana, de Carvalho Mamede, Meininger Vincent, Salachas François, Millecamps Stéphanie, Grošelj Leja Dolenc, Brands William J, Schellevis Raymond D, Robinson Matthew R, de Jong Simone, Võsa Urmo, van der Spek Rick A A, Pulit Sara L, Diekstra Frank P, McLaughlin Russell L, Dekker Annelot M, Shatunov Aleksey, Yang Jian, Fogh Isabella, Harschnitz Oliver, van Eijk Kristel R, Kenna Kevin P, Jones Ashley R, Sproviero William, Blokhuis Anna M, Koppers Max, Tazelaar Gijs H P, van Doormaal Perry Tc, van Rheenen Wouter, Colville Shuna, Cichon Sven, Maurel Cindy, Andres Christian R, Radivojkov-Blagojevic Milena, Lichtner Peter, Meitinger Thomas, Parman Yesim, Hamzeiy Hamid, Tunca Ceren, Basak A Nazli, Bensimon Gilbert, Landwehrmeyer Bernhard, Rietschel Marcella, Franke Andre, Lieb Wolfgang, Tittmann Lukas, Wood Nicholas W, Dürr Alexandra, Saker-Delye Safaa, Payan Christine A M, Brice Alexis, McCluskey Leo, Elman Lauren, Topp Simon, Malaspina Andrea, Fratta Pietro, Sidle Katie, Pittman Alan, Orrell Richard W, Hardy John, Shaw Pamela J, Morrison Karen E, Petri Susanne, Abdulla Susanne, Trojanowski John Q, Van Deerlin Vivianna M, Lomen-Hoerth Catherine, Wiedau-Pazos Martina, Staats Kim A, Ophoff Roel A, Meyer Thomas, Sendtner Michael, Drepper Carsten, Swingler Robert
Percutaneous endoscopic gastrostomy in amyotrophic lateral sclerosis: a prospective observational study
Dorst J, Dupuis L, Petri S, Kollewe K, Meyer T, Burkhardt C, Czell D, Weber M, Ludolph A. Percutaneous endoscopic gastrostomy in amyotrophic lateral sclerosis: a prospective observational study. Journal of neurology 2015; [Epub ahead of print]
Jan 25, 2015Percutaneous endoscopic gastrostomy in amyotrophic lateral sclerosis: a prospective observational study
Jan 25, 2015Journal of neurology 2015; [Epub ahead of print]
Dorst Johannes, Dupuis Luc, Petri Susanne, Kollewe Katja, Meyer Thomas, Burkhardt Christian, Czell David, Weber Markus, Ludolph Albert
Percutaneous endoscopic gastrostomy in amyotrophic lateral sclerosis: a prospective observational study
Dorst J, Schrank B, Grehl T, Kettemann D, Frisch G, Meyer T, Vielhaber S, Hanisch F, Burkhardt C, Czell D, Weber M, Wolf J, Abdulla S, Kollewe K, Petri S, Dupuis L, Ludolph A. Percutaneous endoscopic gastrostomy in amyotrophic lateral sclerosis: a prospective observational study. J Neurol 2015; 262:849-58.
Jan 25, 2015Percutaneous endoscopic gastrostomy in amyotrophic lateral sclerosis: a prospective observational study
Jan 25, 2015J Neurol 2015; 262:849-58
Dorst Johannes, Schrank Bertold, Grehl Torsten, Kettemann Dagmar, Frisch Gabriele, Meyer Thomas, Vielhaber Stefan, Hanisch Frank, Burkhardt Christian, Czell David, Weber Markus, Wolf Joachim, Abdulla Susanne, Kollewe Katja, Petri Susanne, Dupuis Luc, Ludolph Albert C
Neoadjuvant chemoradiation therapy with gemcitabine/cisplatin and surgery versus immediate surgery in resectable pancreatic cancer: results of the first prospective randomized phase II trial
Golcher H, Fietkau R, Merkel S, Meyer T, Grabenbauer G, Schreiber S, Jungnickel H, Bruns C, Bechstein W, Marti L, Witzigmann H, Brunner T, Hohenberger W. Neoadjuvant chemoradiation therapy with gemcitabine/cisplatin and surgery versus immediate surgery in resectable pancreatic cancer: results of the first prospective randomized phase II trial. Strahlenther Onkol 2014; 191:7-16.
Sep 25, 2014Neoadjuvant chemoradiation therapy with gemcitabine/cisplatin and surgery versus immediate surgery in resectable pancreatic cancer: results of the first prospective randomized phase II trial
Sep 25, 2014Strahlenther Onkol 2014; 191:7-16
Golcher Henriette, Fietkau Rainer, Merkel Susanne, Meyer Thomas, Grabenbauer Gerhard G, Schreiber Stefan, Jungnickel Henry, Bruns Christiane, Bechstein Wolf-Otto, Marti Lukas, Witzigmann Helmut, Brunner Thomas B, Hohenberger Werner
Ataxin-2 intermediate-length polyglutamine expansions in European ALS patients
Lee T, Andersen P, Bonini N, Gispert S, Auburger G, Tysnes O, Meyer T, de Carvalho M, Gredal O, Grehl T, Weber M, Ingre C, Li Y, Gitler A. Ataxin-2 intermediate-length polyglutamine expansions in European ALS patients. Hum Mol Genet 2011; 20:1697-700.
Feb 3, 2011Ataxin-2 intermediate-length polyglutamine expansions in European ALS patients
Feb 3, 2011Hum Mol Genet 2011; 20:1697-700
Lee Teresa, Andersen Peter M, Bonini Nancy M, Gispert Suzana, Auburger Georg, Tysnes Ole-Björn, Meyer Thomas, de Carvalho Mamede, Gredal Ole, Grehl Torsten, Weber Markus, Ingre Caroline, Li Yun R, Gitler Aaron D