Freddy Radtke
Notch signaling drives intestinal graft-versus-host disease in mice and nonhuman primates.
Tkachev V, Vanderbeck A, Perkey E, Furlan S, McGuckin C, Gómez Atria D, Gerdemann U, Rui X, Lane J, Hunt D, Zheng H, Colonna L, Hoffman M, Yu A, Outen R, Kelly S, Allman A, Koch U, Radtke F, Ludewig B, Burbach B, Shimizu Y, Panoskaltsis-Mortari A, Chen G, Carpenter S, Harari O, Kuhnert F, Thurston G, Blazar B, Kean L, Maillard I. Notch signaling drives intestinal graft-versus-host disease in mice and nonhuman primates. Sci Transl Med 2023; 15:eadd1175.
Jun 28, 2023Notch signaling drives intestinal graft-versus-host disease in mice and nonhuman primates.
Jun 28, 2023Sci Transl Med 2023; 15:eadd1175
Tkachev Victor, Vanderbeck Ashley, Perkey Eric, Furlan Scott N, McGuckin Connor, Gómez Atria Daniela, Gerdemann Ulrike, Rui Xianliang, Lane Jennifer, Hunt Daniel J, Zheng Hengqi, Colonna Lucrezia, Hoffman Michelle, Yu Alison, Outen Riley, Kelly Samantha, Allman Anneka, Koch Ute, Radtke Freddy, Ludewig Burkhard, Burbach Brandon, Shimizu Yoji, Panoskaltsis-Mortari Angela, Chen Guoying, Carpenter Stephen M, Harari Olivier, Kuhnert Frank, Thurston Gavin, Blazar Bruce R, Kean Leslie S, Maillard Ivan
Stromal Notch ligands foster lymphopenia-driven functional plasticity and homeostatic proliferation of naive B cells.
Gómez Atria D, Gaudette B, Londregan J, Kelly S, Perkey E, Allman A, Srivastava B, Koch U, Radtke F, Ludewig B, Siebel C, Ryan R, Robertson T, Burkhardt J, Pear W, Allman D, Maillard I. Stromal Notch ligands foster lymphopenia-driven functional plasticity and homeostatic proliferation of naive B cells. J Clin Invest 2022; 132
Jul 1, 2022Stromal Notch ligands foster lymphopenia-driven functional plasticity and homeostatic proliferation of naive B cells.
Jul 1, 2022J Clin Invest 2022; 132
Gómez Atria Daniela, Gaudette Brian T, Londregan Jennifer, Kelly Samantha, Perkey Eric, Allman Anneka, Srivastava Bhaskar, Koch Ute, Radtke Freddy, Ludewig Burkhard, Siebel Christian W, Ryan Russell Jh, Robertson Tanner F, Burkhardt Janis K, Pear Warren S, Allman David, Maillard Ivan
GCNT1-Mediated -Glycosylation of the Sialomucin CD43 Is a Sensitive Indicator of Notch Signaling in Activated T Cells
Perkey E, Labrecque N, Nolz J, Brennan T, Siebel C, Blazar B, Ludewig B, Radtke F, Koch U, Granadier D, Dils A, Chung J, Carrington L, Maurice De Sousa D, Maillard I. GCNT1-Mediated -Glycosylation of the Sialomucin CD43 Is a Sensitive Indicator of Notch Signaling in Activated T Cells. J Immunol 2020; 204:1674-1688.
Feb 14, 2020GCNT1-Mediated -Glycosylation of the Sialomucin CD43 Is a Sensitive Indicator of Notch Signaling in Activated T Cells
Feb 14, 2020J Immunol 2020; 204:1674-1688
Perkey Eric, Labrecque Nathalie, Nolz Jeffrey, Brennan Todd V, Siebel Christian W, Blazar Bruce R, Ludewig Burkhard, Radtke Freddy, Koch Ute, Granadier David, Dils Alexander, Chung Jooho, Carrington Léolène, Maurice De Sousa Dave, Maillard Ivan
Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands
Chung J, Onder L, Yan M, Reddy P, Blazar B, Huang A, Brennan T, Bishop D, Ludewig B, Siebel C, Radtke F, Luther S, Chai Q, Tran I, Ebens C, Perkey E, Radojcic V, Koch U, Scarpellino L, Tong A, Allen F, Wood S, Feng J, Friedman A, Granadier D, Maillard I. Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands. J Clin Invest 2017; 127:1574-1588.
Mar 20, 2017Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands
Mar 20, 2017J Clin Invest 2017; 127:1574-1588
Chung Jooho, Onder Lucas, Yan Minhong, Reddy Pavan, Blazar Bruce R, Huang Alex Y, Brennan Todd V, Bishop D Keith, Ludewig Burkhard, Siebel Christian W, Radtke Freddy, Luther Sanjiv A, Chai Qian, Tran Ivy T, Ebens Christen L, Perkey Eric, Radojcic Vedran, Koch Ute, Scarpellino Leonardo, Tong Alexander, Allen Frederick, Wood Sherri, Feng Jiane, Friedman Ann, Granadier David, Maillard Ivan
Specific fibroblastic niches in secondary lymphoid organs orchestrate distinct Notch-regulated immune responses
Fasnacht N, Luther S, Ludewig B, Tacchini-Cottier F, MacDonald H, Pinschewer D, Kallert S, Onder L, Chai Q, Auderset F, Favre S, Koch U, Huang H, Radtke F. Specific fibroblastic niches in secondary lymphoid organs orchestrate distinct Notch-regulated immune responses. J Exp Med 2014; 211:2265-79.
Oct 13, 2014Specific fibroblastic niches in secondary lymphoid organs orchestrate distinct Notch-regulated immune responses
Oct 13, 2014J Exp Med 2014; 211:2265-79
Fasnacht Nicolas, Luther Sanjiv A, Ludewig Burkhard, Tacchini-Cottier Fabienne, MacDonald H Robson, Pinschewer Daniel D, Kallert Sandra, Onder Lucas, Chai Qian, Auderset Floriane, Favre Stéphanie, Koch Ute, Huang Hsin-Ying, Radtke Freddy
Disruption of Notch1 induces vascular remodeling, intussusceptive angiogenesis, and angiosarcomas in livers of mice
Dill M, Heim M, Radtke F, Meili-Butz S, Terracciano L, Tornillo L, Hlushchuk R, Djonov V, Rothweiler S, Semela D. Disruption of Notch1 induces vascular remodeling, intussusceptive angiogenesis, and angiosarcomas in livers of mice. Gastroenterology 2012; 142:967-977.e2.
Jan 12, 2012Disruption of Notch1 induces vascular remodeling, intussusceptive angiogenesis, and angiosarcomas in livers of mice
Jan 12, 2012Gastroenterology 2012; 142:967-977.e2
Dill Michael T, Heim Markus H, Radtke Freddy, Meili-Butz Silvia, Terracciano Luigi, Tornillo Luigi, Hlushchuk Ruslan, Djonov Valentin, Rothweiler Sonja, Semela David