Marie Loh
A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure
Bowden D, Snieder H, Smith J, Sitlani C, Sever P, Seshadri S, Scott W, Schreiner P, Schmidt C, Sandow K, Salako B, Sabanayagam C, Rudan I, Rose L, Robinson J, Robino A, Ridker P, Starr J, Strauch K, Tang H, Boehnke M, Becker D, Zonderman A, Yuan J, Yao J, Wojczynski M, Wilson G, Williams C, Wei W, Wang Y, Wang L, Waldenberger M, Uitterlinden A, Tham Y, Teo Y, Taylor K, Rice T, Renström F, Raitakari O, Metspalu A, Meitinger T, Mahajan A, Mägi R, Louie T, Long J, Lohman K, Loh M, Liu Y, Liu K, Liu J, Liu J, Liu C, Lin S, Lim S, Lifelines Cohort Study, Milani L, Momozawa Y, Morris A, Polasek O, Peyser P, Peters A, Pedersen N, Pankow J, Palmer N, Palmas W, Padmanabhan S, Ogunniyi A, North K, Norris J, Nasri U, Nalls M, Murray A, Munson P, Mosley T, Li Y, Chasman D, Hayward C, Fox E, Kelly T, Mook-Kanamori D, Arnett D, Sims M, van Dam R, Psaty B, O'Connell J, Levy D, Kritchevsky S, Kardia S, Gudnason V, Evans M, Cooper R, Bouchard C, Fornage M, Rotimi C, Province M, Rao D, Cupples L, Morrison A, Munroe P, Rice K, Elliott P, Caulfield M, Gauderman W, Bierut L, Zhu X, Rotter J, Reiner A, Loos R, Wong T, Tai E, van Duijn C, Laurie C, Kamatani Y, Zheng W, Kooner J, Kato N, Jonas J, Hung Y, Horta B, Gieger C, Gasparini P, Froguel P, Freedman B, Franks P, Forrester T, Farrall M, Esko T, Deary I, de Faire U, Chen Y, Laakso M, Lehtimäki T, Liang K, Wu T, Wickremasinghe A, Weir D, Watkins H, Wareham N, Wagenknecht L, van der Harst P, Shu X, Scott J, Samani N, Rettig R, Redline S, Pereira A, Oldehinkel A, Newman A, Magnusson P, Chambers J, Lewis C, Yanek L, Leander K, Kühnel B, Kasturiratne A, Kähönen M, Jackson A, Hsu F, Horimoto A, Hartwig F, Harris S, Goel A, Giulianini F, Gao C, Gandin I, Divers J, Chen X, Chai J, Lee W, Lin K, 'an Luan J, Wen W, Weiss S, Ware E, Wang Y, Wang H, Varga T, van der Most P, Takeuchi F, Stančáková A, Sheu W, Scott R, Schupf N, Rauramaa R, Nelson C, He M, McKenzie C, Boissel M, Amini M, Alver M, Li C, Musani S, Marten J, Vojinovic D, Sim X, Cheng C, Lu Y, Franceschini N, Guo X, Ntalla I, Schwander K, Kraja A, Brown M, Bentley A, de Las Fuentes L, Winkler T, Feitosa M, Kilpeläinen T, Richard M, Sofer T, Matoba N, Zhou Y, Zhao W, Warren H, Tayo B, Tajuddin S, Smith A, Rankinen T, Manning A, Liu Y, Dorajoo R, Bartz T, Aschard H, Aslibekyan S, Noordam R, Sung Y, Lehne B, Howard B, Hofman A, Hirata M, Heng C, Heikkinen S, He J, Harris T, Hagenaars S, Gupta P, Gu D, Gu C, Graff M, Gigante B, GIANT Consortium, Gao H, Friedlander Y, Hunt S, Irvin M, Jia Y, Launer L, Langenberg C, Langefeld C, Kuusisto J, Kubo M, Krieger J, Kooperberg C, Komulainen P, Koistinen H, Koh W, Khor C, Kerrison N, Kaufman J, Katsuya T, Justice A, Joehanes R, Franco O, Forouhi N, Fisher V, Caizheng Y, Cade B, Cabrera C, Broeckel U, Brody J, Braund P, Bottinger E, Boerwinkle E, Bielak L, Barr R, Aung T, Arking D, Amin N, Alfred T, Afaq S, Zhao J, Campbell A, Canouil M, Chakravarti A, Faul J, Evangelou E, Ehret G, Eaton C, Duan Q, Dörr M, Debette S, de Silva H, de Mutsert R, Connell J, Collins F, COGENT-Kidney Consortium, Cocca M, Christensen K, Chauhan G, CHARGE Neurology Working Group, Zhang W. A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. Am J Hum Genet 2018; 102:375-400.
15.02.2018A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure
15.02.2018Am J Hum Genet 2018; 102:375-400
Bowden Donald W, Snieder Harold, Smith Jennifer A, Sitlani Colleen M, Sever Peter, Seshadri Sudha, Scott William R, Schreiner Pamela J, Schmidt Carsten O, Sandow Kevin, Salako Babatunde L, Sabanayagam Charumathi, Rudan Igor, Rose Lynda M, Robinson Jennifer G, Robino Antonietta, Ridker Paul M, Starr John M, Strauch Konstantin, Tang Hua, Boehnke Michael, Becker Diane M, Zonderman Alan B, Yuan Jian-Min, Yao Jie, Wojczynski Mary K, Wilson Gregory, Williams Christine, Wei Wen Bin, Wang Ya X, Wang Lihua, Waldenberger Melanie, Uitterlinden André G, Tham Yih Chung, Teo Yik Ying, Taylor Kent D, Rice Treva K, Renström Frida, Raitakari Olli T, Metspalu Andres, Meitinger Thomas, Mahajan Anubha, Mägi Reedik, Louie Tin, Long Jirong, Lohman Kurt K, Loh Marie, Liu Yeheng, Liu Kiang, Liu Jingmin, Liu Jianjun, Liu Ching-Ti, Lin Shiow, Lim Sing Hui, Lifelines Cohort Study, Milani Lili, Momozawa Yukihide, Morris Andrew P, Polasek Ozren, Peyser Patricia A, Peters Annette, Pedersen Nancy L, Pankow James S, Palmer Nicholette D, Palmas Walter R, Padmanabhan Sandosh, Ogunniyi Adesola, North Kari, Norris Jill M, Nasri Ubaydah, Nalls Mike A, Murray Alison D, Munson Peter, Mosley Thomas H, Li Yize, Chasman Daniel I, Hayward Caroline, Fox Ervin R, Kelly Tanika N, Mook-Kanamori Dennis O, Arnett Donna K, Sims Mario, van Dam Rob M, Psaty Bruce M, O'Connell Jeff R, Levy Daniel, Kritchevsky Stephen B, Kardia Sharon L R, Gudnason Vilmundur, Evans Michele K, Cooper Richard S, Bouchard Claude, Fornage Myriam, Rotimi Charles N, Province Michael A, Rao Dabeeru C, Cupples L Adrienne, Morrison Alanna C, Munroe Patricia B, Rice Kenneth, Elliott Paul, Caulfield Mark J, Gauderman W James, Bierut Laura J, Zhu Xiaofeng, Rotter Jerome I, Reiner Alex P, Loos Ruth J F, Wong Tien Yin, Tai E Shyong, van Duijn Cornelia M, Laurie Cathy C, Kamatani Yoichiro, Zheng Wei, Kooner Jaspal S, Kato Norihiro, Jonas Jost B, Hung Yi-Jen, Horta Bernardo Lessa, Gieger Christian, Gasparini Paolo, Froguel Philippe, Freedman Barry I, Franks Paul W, Forrester Terrence, Farrall Martin, Esko Tõnu, Deary Ian J, de Faire Ulf, Chen Yii-Der Ida, Laakso Markku, Lehtimäki Terho, Liang Kae-Woei, Wu Tangchun, Wickremasinghe Ananda R, Weir David R, Watkins Hugh, Wareham Nicholas J, Wagenknecht Lynne E, van der Harst Pim, Shu Xiao-Ou, Scott James, Samani Nilesh J, Rettig Rainer, Redline Susan, Pereira Alexandre C, Oldehinkel Albertine J, Newman Anne B, Magnusson Patrik K E, Chambers John C, Lewis Cora E, Yanek Lisa R, Leander Karin, Kühnel Brigitte, Kasturiratne Anuradhani, Kähönen Mika, Jackson Anne U, Hsu Fang-Chi, Horimoto Andrea R V R, Hartwig Fernando Pires, Harris Sarah E, Goel Anuj, Giulianini Franco, Gao Chuan, Gandin Ilaria, Divers Jasmin, Chen Xu, Chai Jin Fang, Lee Wen-Jane, Lin Keng-Hung, 'an Luan Jian, Wen Wanqing, Weiss Stefan, Ware Erin B, Wang Yajuan, Wang Heming, Varga Tibor V, van der Most Peter J, Takeuchi Fumihiko, Stančáková Alena, Sheu Wayne H H, Scott Robert A, Schupf Nicole, Rauramaa Rainer, Nelson Christopher P, He Meian, McKenzie Colin A, Boissel Mathilde, Amini Marzyeh, Alver Maris, Li Changwei, Musani Solomon K, Marten Jonathan, Vojinovic Dina, Sim Xueling, Cheng Ching-Yu, Lu Yingchang, Franceschini Nora, Guo Xiuqing, Ntalla Ioanna, Schwander Karen, Kraja Aldi T, Brown Michael R, Bentley Amy R, de Las Fuentes Lisa, Winkler Thomas W, Feitosa Mary F, Kilpeläinen Tuomas O, Richard Melissa A, Sofer Tamar, Matoba Nana, Zhou Yanhua, Zhao Wei, Warren Helen R, Tayo Bamidele O, Tajuddin Salman M, Smith Albert Vernon, Rankinen Tuomo, Manning Alisa K, Liu Yongmei, Dorajoo Rajkumar, Bartz Traci M, Aschard Hugues, Aslibekyan Stella, Noordam Raymond, Sung Yun J, Lehne Benjamin, Howard Barbara V, Hofman Albert, Hirata Makoto, Heng Chew-Kiat, Heikkinen Sami, He Jiang, Harris Tamara B, Hagenaars Saskia P, Gupta Preeti, Gu Dongfeng, Gu C Charles, Graff Misa, Gigante Bruna, GIANT Consortium, Gao He, Friedlander Yechiel, Hunt Steven, Irvin Marguerite R, Jia Yucheng, Launer Lenore J, Langenberg Claudia, Langefeld Carl D, Kuusisto Johanna, Kubo Michiaki, Krieger Jose E, Kooperberg Charles, Komulainen Pirjo, Koistinen Heikki A, Koh Woon-Puay, Khor Chiea Chuen, Kerrison Nicola D, Kaufman Joel, Katsuya Tomohiro, Justice Anne E, Joehanes Roby, Franco Oscar H, Forouhi Nita G, Fisher Virginia A, Caizheng Yu, Cade Brian, Cabrera Claudia P, Broeckel Ulrich, Brody Jennifer A, Braund Peter S, Bottinger Erwin P, Boerwinkle Eric, Bielak Lawrence F, Barr R Graham, Aung Tin, Arking Dan, Amin Najaf, Alfred Tamuno, Afaq Saima, Zhao Jing Hua, Campbell Archie, Canouil Mickaël, Chakravarti Aravinda, Faul Jessica D, Evangelou Evangelos, Ehret Georg, Eaton Charles B, Duan Qing, Dörr Marcus, Debette Stephanie, de Silva H Janaka, de Mutsert Renée, Connell John M, Collins Francis S, COGENT-Kidney Consortium, Cocca Massimiliano, Christensen Kaare, Chauhan Ganesh, CHARGE Neurology Working Group, Zhang Weihua
Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits
Zhao W, Stott D, Staessen J, Snieder H, Slagboom P, Silbernagel G, Siemelink M, Sennblad B, Scott R, Schurmann C, Scholtens S, Schlessinger D, Savonen K, Sattar N, Sarzynski M, Sanna S, Rudan I, Bien S, Swertz M, Swift A, Taylor K, Wright A, Wong A, Wolffenbuttel B, Willemsen G, Wild S, Westendorp R, Waldenberger M, Waeber G, Vonk J, Völzke H, Vohl M, Vandenput L, Uitterlinden A, Tuomilehto J, Thuillier D, Thorand B, Tayo B, Rose L, Ridker P, Rice T, McKenzie C, Martin N, Marques-Vidal P, Männikkö R, Madden P, Lupoli S, Ludolph-Donislawski A, Lubke G, Luben R, Lorentzon M, Loh M, Lobbens S, Linneberg A, Lindgren C, Lind L, Lee N, Leander K, McKnight B, Mellström D, Menni C, Rawal R, Rasmussen-Torvik L, Rao D, Rankinen T, Raitakari O, Porteous D, Pisinger C, Peyser P, Padmanabhan S, Ong K, Olden M, Oldehinkel A, Nolte I, Nauck M, Narisu N, Musk A, Montgomery G, Launer L, Cupples L, Whitfield J, Weir D, Wareham N, Vollenweider P, Vestergaard H, van der Harst P, Tremoli E, Tiemeier H, Strauch K, Sørensen T, Smith B, Rauramaa R, Qi L, Psaty B, Polasek O, Peters U, Peters A, Wilson J, Tyrrell J, Frayling T, North K, Borecki I, Liu C, Kilpeläinen T, Loos R, Marchini J, Mohlke K, Heid I, van Duijn C, Strachan D, Spector T, Hunter D, Hirschhorn J, Fox C, Deloukas P, Boehnke M, Barroso I, Pedersen O, Pasterkamp G, Palmer L, Froguel P, Franks P, Ferrucci L, Faire U, Cusi D, Cucca F, Cooper R, Chines P, Chen Y, Chasman D, Bruinenberg M, Bouchard C, Boomsma D, Böger C, Bandinelli S, Balkau B, Baldassarre D, Gordon-Larsen P, Grabe H, Gudnason V, Ohlsson C, Morris A, Metspalu A, McCarthy M, März W, Marchand L, Lehtimäki T, Laakso M, Kuh D, Kooner J, Kivimäki M, Kardia S, Wouter Jukema J, Johnson A, Hveem K, Hayward C, Haiman C, Zillikens M, Langenberg C, Zhang W, Pérusse L, Navarro P, Müller-Nurasyid M, Middelberg R, Marten J, Manichaikul A, Mangino M, Lyytikäinen L, Luan J, Lim U, Kumari M, Komulainen P, Kleber M, Kinnunen L, Kanoni S, Justesen J, Jackson A, Pervjakova N, Sarti C, Smith A, Yengo L, Wu Y, Vitart V, Vink J, Verweij N, Vedantam S, van Vliet-Ostaptchouk J, van der Most P, van der Laan S, Trompet S, Teumer A, Tanaka T, Sung Y, Stringham H, Strawbridge R, Stančáková A, Smith J, Huffman J, Huang T, Horikoshi M, Kutalik Z, Eicher J, Perez J, Lim E, Heard-Costa N, Chu A, Ahluwalia T, Ngwa J, Hadley D, Czajkowski J, Deng X, Barata L, Young K, Fisher V, Graff M, Feitosa M, Winkler T, Xue L, Mahajan A, Renström F, Neergaard Harder M, Gorski M, Fischer K, Eriksson J, Direk N, Corre T, Coggeshall S, Chittani M, Cadby G, Bragg J, Bonnefond A, Bielak L, Amin N, Alfred T, Ahmad S, Qi Q, Wu J, Justice A, Lakka T, Homuth G, Holmen O, Hollensted M, Hocking L, Hindorff L, Hernandez D, Heath A, Hastie N, Hassinen M, Hartman C, Harris T, Hansen T, Hamsten A, Hallmans G, Haitjema S, Grarup N, Grammer T, Jan Hottenga J, Huang J, Hung J, Kvaløy K, Kuusisto J, Krämer B, Kooperberg C, Kolovou G, Kolcic I, Koistinen H, Karlsson M, Kähönen M, Juonala M, Jørgensen M, Jhun M, Jarvelin M, Jansson J, James A, Ingelsson E, Hutri-Kähönen N, Grallert H, Gong J, Glorioso N, Braga D, Bottinger E, Bonnycastle L, Boerwinkle E, Blangero J, Biffar R, Bergmann S, Bergman R, Beilby J, Bartz T, Bakker S, Afzal U, Afaq S, Adair L, Abecasis G, Zubair N, Zimmermann M, Buckley B, Buyske S, Campbell H, Gigante B, Gertow K, Forrester T, Ford I, Faul J, Esko T, Eriksson A, Eiriksdottir G, den Ruijter H, Delgado G, Dedoussis G, de Geus E, de Craen A, de Borst G, Curran J, Collins F, Chambers J, Hua Zhao J. Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. Nat Commun 2017; 8:14977.
26.04.2017Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits
26.04.2017Nat Commun 2017; 8:14977
Zhao Wei, Stott David J, Staessen Jan A, Snieder Harold, Slagboom P Eline, Silbernagel Günther, Siemelink Marten A, Sennblad Bengt, Scott Robert A, Schurmann Claudia, Scholtens Salome, Schlessinger David, Savonen Kai, Sattar Naveed, Sarzynski Mark A, Sanna Serena, Rudan Igor, Bien Stephanie A, Swertz Morris A, Swift Amy J, Taylor Kent D, Wright Alan F, Wong Andrew, Wolffenbuttel Bruce H R, Willemsen Gonneke, Wild Sarah, Westendorp R G J, Waldenberger Melanie, Waeber Gerard, Vonk Judith M, Völzke Henry, Vohl Marie-Claude, Vandenput Liesbeth, Uitterlinden André G, Tuomilehto Jaakko, Thuillier Dorothée, Thorand Barbara, Tayo Bamidele O, Rose Lynda M, Ridker Paul M, Rice Treva, McKenzie Colin A, Martin Nicholas G, Marques-Vidal Pedro, Männikkö Reija, Madden Pamela A F, Lupoli Sara, Ludolph-Donislawski Anja, Lubke Gitta, Luben Robert, Lorentzon Mattias, Loh Marie, Lobbens Stephane, Linneberg Allan, Lindgren Cecilia M, Lind Lars, Lee Nanette R, Leander Karin, McKnight Barbara, Mellström Dan, Menni Cristina, Rawal Rajesh, Rasmussen-Torvik Laura J, Rao D C, Rankinen Tuomo, Raitakari Olli T, Porteous David J, Pisinger Charlotta, Peyser Patricia A, Padmanabhan Sandosh, Ong Ken K, Olden Matthias, Oldehinkel Albertine J, Nolte Ilja M, Nauck Matthias, Narisu Narisu, Musk Aw Bill, Montgomery Grant W, Launer Lenore J, Cupples L Adrienne, Whitfield John B, Weir David R, Wareham Nicholas J, Vollenweider Peter, Vestergaard Henrik, van der Harst Pim, Tremoli Elena, Tiemeier Henning, Strauch Konstantin, Sørensen Thorkild I A, Smith Blair H, Rauramaa Rainer, Qi Lu, Psaty Bruce M, Polasek Ozren, Peters Ulrike, Peters Annette, Wilson James F, Tyrrell Jessica, Frayling Timothy M, North Kari E, Borecki Ingrid B, Liu Ching-Ti, Kilpeläinen Tuomas O, Loos Ruth J F, Marchini Jonathan, Mohlke Karen L, Heid Iris M, van Duijn Cornelia M, Strachan David P, Spector Tim D, Hunter David J, Hirschhorn Joel N, Fox Caroline S, Deloukas Panagiotis, Boehnke Michael, Barroso Inês, Pedersen Oluf, Pasterkamp Gerard, Palmer Lyle J, Froguel Philippe, Franks Paul W, Ferrucci Luigi, Faire Ulf de, Cusi Daniele, Cucca Francesco, Cooper Richard S, Chines Peter S, Chen Yii-DerIda, Chasman Daniel I, Bruinenberg Marcel, Bouchard Claude, Boomsma Dorret I, Böger Carsten A, Bandinelli Stefania, Balkau Beverley, Baldassarre Damiano, Gordon-Larsen Penny, Grabe Hans-Jörgen, Gudnason Vilmundur, Ohlsson Claes, Morris Andrew P, Metspalu Andres, McCarthy Mark I, März Winfried, Marchand Loic Le, Lehtimäki Terho, Laakso Markku, Kuh Diana, Kooner Jaspal S, Kivimäki Mika, Kardia Sharon L R, Wouter Jukema J, Johnson Andrew D, Hveem Kristian, Hayward Caroline, Haiman Christopher A, Zillikens M Carola, Langenberg Claudia, Zhang Weihua, Pérusse Louis, Navarro Pau, Müller-Nurasyid Martina, Middelberg Rita P S, Marten Jonathan, Manichaikul Ani, Mangino Massimo, Lyytikäinen Leo-Pekka, Luan Jian'an, Lim Unhee, Kumari Meena, Komulainen Pirjo, Kleber Marcus E, Kinnunen Leena, Kanoni Stavroula, Justesen Johanne Marie, Jackson Anne U, Pervjakova Natalia, Sarti Cinzia, Smith Albert Vernon, Yengo Loic, Wu Ying, Vitart Veronique, Vink Jacqueline M, Verweij Niek, Vedantam Sailaja L, van Vliet-Ostaptchouk Jana V, van der Most Peter J, van der Laan Sander W, Trompet Stella, Teumer Alexander, Tanaka Toshiko, Sung Yun Ju, Stringham Heather M, Strawbridge Rona J, Stančáková Alena, Smith Jennifer A, Huffman Jennifer E, Huang Tao, Horikoshi Momoko, Kutalik Zoltán, Eicher John D, Perez Jeremiah, Lim Elise, Heard-Costa Nancy L, Chu Audrey Y, Ahluwalia Tarunveer S, Ngwa Julius S, Hadley David, Czajkowski Jacek, Deng Xuan, Barata Llilda, Young Kristin, Fisher Virginia A, Graff Misa, Feitosa Mary F, Winkler Thomas W, Xue Luting, Mahajan Anubha, Renström Frida, Neergaard Harder Marie, Gorski Mathias, Fischer Krista, Eriksson Joel, Direk Nese, Corre Tanguy, Coggeshall Scott, Chittani Martina, Cadby Gemma, Bragg Jennifer, Bonnefond Amélie, Bielak Lawrence F, Amin Najaf, Alfred Tamuno, Ahmad Shafqat, Qi Qibin, Wu Joseph, Justice Anne E, Lakka Timo A, Homuth Georg, Holmen Oddgeir L, Hollensted Mette, Hocking Lynne J, Hindorff Lucia, Hernandez Dena, Heath Andrew C, Hastie Nicholas D, Hassinen Maija, Hartman Catharina A, Harris Tamara B, Hansen Torben, Hamsten Anders, Hallmans Göran, Haitjema Saskia, Grarup Niels, Grammer Tanja B, Jan Hottenga Jouke, Huang Jie, Hung Joseph, Kvaløy Kirsti, Kuusisto Johanna, Krämer Bernhard K, Kooperberg Charles, Kolovou Genovefa, Kolcic Ivana, Koistinen Heikki A, Karlsson Magnus, Kähönen Mika, Juonala Markus, Jørgensen Marit E, Jhun Min A, Jarvelin Marjo-Riitta, Jansson John-Olov, James Alan L, Ingelsson Erik, Hutri-Kähönen Nina, Grallert Harald, Gong Jian, Glorioso Nicola, Braga Daniele, Bottinger Erwin, Bonnycastle Lori L, Boerwinkle Eric, Blangero John, Biffar Reiner, Bergmann Sven, Bergman Richard N, Beilby John, Bartz Traci M, Bakker Stephan J L, Afzal Uzma, Afaq Saima, Adair Linda S, Abecasis Gonçalo R, Zubair Niha, Zimmermann Martina E, Buckley Brendan M, Buyske Steve, Campbell Harry, Gigante Bruna, Gertow Karl, Forrester Terrence, Ford Ian, Faul Jessica D, Esko Tõnu, Eriksson Anna L, Eiriksdottir Gudny, den Ruijter Hester M, Delgado Graciela E, Dedoussis George, de Geus Eco J C, de Craen Anton J M, de Borst Gert J, Curran Joanne E, Collins Francis S, Chambers John C, Hua Zhao Jing